[1]张金山.放射性核素细胞凋亡显像[J].国际放射医学核医学杂志,2004,28(1):6-8,25.
 ZHANG Jin-shan.Apoptosis radionuclide imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(1):6-8,25.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
28
期数:
2004年第1期
页码:
6-8,25
栏目:
核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Apoptosis radionuclide imaging
作者:
张金山
510150 广州, 广州市第二人民医院核医学科
Author(s):
ZHANG Jin-shan
Department of Nuclear Medicine, Guangzhou Second People’s Hospital, Guangzhou 510150, China
关键词:
放射性核素显像细胞凋亡膜联蛋白V
Keywords:
radionuclide imagingapoptosisannexin V
分类号:
R817.4
摘要:
放射性核素细胞凋亡显像具有直观、无创伤和实时在体观察细胞凋亡等特点,对于脑、心肌细胞缺血再灌注损伤的观察,器官移植排斥反应的监测,肿瘤放疗和化疗效果的评估等方面的应用前景良好,但仍有许多问题有待于进一步探讨。
Abstract:
Apoptosis radionuclide imaging is a novel method for the detection of apoptosis, characterised with direct, noninvasive and real-time imaging. It is useful in the observation of brain and myocardial ischemic reperfusion injury, detection of organ graft rejection and evaluation of tumor chemotherapy and radiotherapy effect, but further investigation should be done.

参考文献/References:

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[14 Thimister PWL, Hofstra L, Liem IH, et al. In vivo detection of Cell Death in the area at risk in acute myocardial infarction[J]. J Nucl Med, 2003, 44(3):391-396.
[15 Vriens PW, Blankenberg FG, Stoot JH, et al. The use of technetium Tc 99m annexin V for in vivo imaging of apoptosis during cardiac allograft rejection[J]. J Thorac Cardiovasc Surg, 1998, 116(5):844-853.
[16 Blankenberg FG, Robbins RC, Stoot JH, et al. Radionuclide imaging of acute lung transplant rejection with annexin V[J].Chest, 2000, 117(3):834-840.
[17 Belhocine T, Steinmetz N, Hustinx R, et al. Increased uptake of the apoptosis-imaging agent 99Tcm recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis[J].Clin Cancer Res, 2002,8(9):2766-2774.
[18 Yang DJ, Azhdarinia A, Wu P, et al. In vivo and vitro measurement of apoptosis in breast cancer cells using 99Tcm-ECannexin V[J]. Cancer Biother radiopharm, 2001, 16(1):73-78.
[19 de Wiele CV, Lahorte C, Oyen W, et al. Nuclear medicine imaging to predict response to radiotherapy:areview[J]. Int Radiat Oncol Biol Phys, 2003, 55(1):5-15."[

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备注/Memo

备注/Memo:
收稿日期:2003-04-03。
更新日期/Last Update: 1900-01-01