[1]王治东.GM-CSF在辐射后的变化及其在辐射损伤治疗中的应用[J].国际放射医学核医学杂志,2003,27(1):38-41.
　WANG Zhi-dong.Expression of GM-CSF level after radiation and application in the radiation injury[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(1):38-41.
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GM-CSF在辐射后的变化及其在辐射损伤治疗中的应用(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
27
期数:
2003年第1期
页码:
38-41
栏目:
放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Expression of GM-CSF level after radiation and application in the radiation injury
作者:
王治东
100850 北京, 军事医学科学院放射医学研究所
Author(s):
WANG Zhi-dong
Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China
关键词:
GM-CSF; 辐射; 造血
Keywords:
GM-CSF; irradiation; hematopoiesis
分类号:
R818.05
摘要:
GM-CSF是较早发现的一种造血生长因子,在某些刺激条件下可由多种细胞合成分泌,能够刺激骨髓造血祖细胞增殖和分化,刺激中性、嗜酸性粒细胞及巨噬细胞增殖和成熟,也可以促进巨核细胞生长,对红细胞生长有辅助调节作用。GM-CSF水平在辐射后动物体内发生明显的变化,对辐射损伤后造血的恢复具有很好的治疗效果。
Abstract:
GM-CSF is the early discovered hematopoietic growth factor. Various kind of cells can synthesize and secreted GM-CSF by some stimulation. GM-CSF can stimulate the proliferation and differentiation of bone marrow hematopoietic progenitor cells and activate the proliferation and maturity of neutrophils, eosinophils, and macrophages. GM-CSF also stimulate growth of megakaryocyte and erythrocyte. Some change of GM-CSF level can be found after radiation in animal, which can accelerate the recovery of radiation injury.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2002-09-27。
作者简介:王治东(1977-),男,硕士研究生,主要从事辐射血液学研究。
更新日期/Last Update: 1900-01-01