参考文献/References:
[1] Spencer SL, Sorger PK. Measuring and modeling apoptosis in single cells. Cell, 2011, 144(6):926-939.
[2] O’Brien MA, Kirby R. Apoptosis:A review of pro-apoptotic and anti-apoptotic pathways and dysregulation in disease[DB/OL].WILEY:J Vet Emerg Crit Care, 2008[2013-03-14]. http://onli-nelibrary.wiley.com/doi/10.1111/j.1476-4431.2008.00363.x/full.
[3] Greer RM, Peyton M, Larsen JE, et al. SMAC Mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-a-independent manner. Can-cer Res, 2011,71(24):7640-7648.
[4] Olsson M, Zhivotovsky B. Caspases and cancer. Cell Death Differ,2011,18(9):1441-1449.
[5] Hartman ML, Czyz M. Anti-apoptotic proteins on guard of melanoma cell survival. Cancer Lett, 2013,331(1):24-34.
[6] Qin S, Yang C, Li S, et al. Smac:Its role in apoptosis induction and use in lung cancer diagnosis and treatment. Cancer Lett, 2012,318(1):9-13.
[7] Du C, Fang M, Li Y, et al. Smac, a mitochondrial protein that pro-motes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell, 2000, 102(1):33-42.
[8] Verhagen AM, Ekert PG, Pakusch M, et al. Identification of DIA-BLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell, 2000,102(1):43-53.
[9] Huang Y, Park YC, Rich RL, et al. Structural basis of caspase inhibition by XIAP:differential roles of the linker versus the BIR domain. Cell, 2001, 104(5):781-790.
[10] Riedl SJ, Renatus M, Schwarzenbacher R, et al. Structural basis for the inhibition of caspase-3 by XIAP. Cell, 2001, 104(5):791-800.
[11] Bao ST, Gui SQ, Lin MS. Relationship between expression of Smacand Survivin and apoptosis of primary hepatocellular carcinoma.Hepatobiliary Pancreat Dis Int, 2006, 5(4):580-583.
[12] Kempkensteffen C, Jager T, Bub J, et al. The equilibrium of XIAP and Smac/DIABLO expression is gradually deranged during the development and progression of testicular germ cell tumours. Int J Androl, 2007, 30(5):476-483.
[13] Kempkensteffen C, Hinz S, Christoph F, et al. Expression levels of the mitochondrial IAP antagonists Smac/DIABLO and Omi/HtrA2 in clear-cell renal cell carcinomas and their prognostic value. J Cancer Res Clin Oncol, 2008, 134(5):543-550.
[14] Martinez-Ruiz G, Maldonado V,Ceballos-Cancino G, et al. Role of Smac/DIABLO in cancer progression. J Exper Clin Cancer Res,2008,27(1):48.
[15] Pluta P, Cebula-Obrzut B, Ehemann V, et al. Correlation of Smac/DIABLO protein expression with the clinico-pathological features of breast cancer patients. Neoplasma, 2011, 58(5):430-435.
[16] Sekimura A, Konishi A, Mizuno K, et al. Expression of Smac/DIA-BLO is a novel prognostic marker in lung cancer. Oncol Rep, 2004,11(4):797-802.
[17] 陈晓,杨春鹿,赵君,等.非小细胞肺癌组织Livin和Smac蛋白表达及其临床意义的研究.中华肿瘤防治杂志,2008(12):144-149.
[18] Dai CH, Li J, Shi SB, et al. Survivin and Smac gene expressions but not livin are predictors of prognosis in non-small cell lung cancer patients treated with adjuvant chemotherapy following surgery. Jpn JClin Oncol, 2010, 40(4):327-335.
[19] 杨莉晖,单春光,黄红梅,等.Smac和survivin在鼻腔鼻窦内翻性乳头状瘤中的表达.临床耳鼻咽喉头颈外科杂志,2013,27(8):407-410.
[20] McNeish IA, Bell S, McKay T, et al. Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-medi-ated pathway. Exper Cell Res, 2003, 286(2):186-198.
[21] Giagkousiklidis S, Vogler M, Westhoff MA, et, al. Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase. Cancer Res, 2005, 65(22):10502-10513.
[22] Fandy TE, Shankar S, Srivastava RK. Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation,and sensitizes TRAIL-resistant breast cancer cells. Mol Cancer,2008,7(1):60.
[23] Chen DJ, Huerta S. Smac mimetics as new cancer therapeutics.Anticancer Drugs, 2009, 20(8):646-658.
[24] Berger R, Jennewein C, Marschall V, et al. NF-kB is required for Smac mimetic-mediated sensitization of glioblastoma cells for y-irradiation-induced apoptosis. Mol Cancer Ther, 2011, 10(10):1867-1875.
[25] Li W, Li B, Giacalone NJ, et al. BV6, an IAP antagonist, activates apoptosis and enhances radiosensitization of non-small cell lung carcinoma in vitro. J Thoracic Oncol, 2011, 6(11):1801-1809.
[26] Ziegler DS, Keating J, Kesari S,et al. A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo. Neuro Oncology, 2011, 13(8):820-829.
[27] Yang D, Zhao Y, Li A Y, et al. Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis. Breast Cancer Res Treat,2012, 133(1):189-199.
[28] Zhang S, Li G,Zhao Y, et al. Smac mimetic SM-164 potentiates AP02L/TRAIL-and doxorubicin-mediated anticancer activity in human hepatocellular carcinoma cells[J/OL]. San Francisco:PLoS One, 2012[2013-03-14]. http://www.ncbi.nlm.nih.gov/pubmed/23240027.
[29] Dai Y, Liu M, Tang W, et al. Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis. Clin Cancer Res, 2008, 14(23):7701-7710.
[30] Huerta S, Gao X, Livingston EH, et al. In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201. Surgery, 2010, 148(2):346-353.
[31] Chen F, Xu C, Du L, et al. Tat-SmacN7 induces radiosensitization in cancer cells through the activation of caspases and induction of apoptosis. Int J Oncol, 2013, 42(3):985.
相似文献/References:
[1]何燕,苏晋,郑晓霞,等.P-糖蛋白抑制剂在PET显像中的应用研究[J].国际放射医学核医学杂志,2016,40(1):1.[doi:10.3760/cma.j.issn.1673-4114.2016.01.001]
He Yan,Su Jin,ZhengXiaoxia,et al.Developing P-glycoprotein inhibitor marked by PET[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):1.[doi:10.3760/cma.j.issn.1673-4114.2016.01.001]
[2]许飞,刘建军,黄钢,等.PET乏氧显像在预测肿瘤乏氧及指导临床治疗中的应用进展[J].国际放射医学核医学杂志,2016,40(1):35.[doi:10.3760/cma.j.issn.1673-4114.2016.01.008]
Xu Fei,Liu Jianjun,Huang Gang,et al.The application of hypoxia imaging with PET in predicting tumor hypoxia and guiding clinical therapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):35.[doi:10.3760/cma.j.issn.1673-4114.2016.01.008]
[3]陈晓艳,张江虹,邵春林.STAT3与辐射敏感相关性的研究进展[J].国际放射医学核医学杂志,2016,40(3):191.[doi:10.3760/cma.j.issn.1673-4114.2016.03.007]
Chen Xiaoyan,Jianghong,Shao Chunlin.Research progresses of correlation between STAT3 and radiosensitivity[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):191.[doi:10.3760/cma.j.issn.1673-4114.2016.03.007]
[4]张俊伶,薛晓蕾,李源,等.富氢水对电离辐射引起胸腺细胞损伤的影响[J].国际放射医学核医学杂志,2015,39(5):358.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 001]
zhang junling,xue xiaolei,li yuan,et al.effects of hydrogen-rich water on radiation-induced thymus injury[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):358.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 001]
[5]赵舒怡,储小飞,樊赛军.血清肿瘤标志物与肿瘤放疗疗效评估的研究进展[J].国际放射医学核医学杂志,2015,39(5):427.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 018]
zhao shuyi,chu xiaofei,fan saijun..progression of study on serum tumor markers in evaluation of tumor radiotherapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):427.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 018]
[6]赵徵鑫,翟贺争,张文艺,等.质子重离子治疗肿瘤的进展[J].国际放射医学核医学杂志,2016,40(5):384.[doi:10.3760/cma.j.issn.1673-4114.2016.05.010]
Zhao Zhixin,Zhai Hezheng,Zhang Wenyi,et al.Development of proton heavy ion in tumor therapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):384.[doi:10.3760/cma.j.issn.1673-4114.2016.05.010]
[7]任佳忠,李永梅,刘岩,等.99Tcm-MDP骨显像胸部异常放射性摄取的原因分析[J].国际放射医学核医学杂志,2016,40(6):459.[doi:10.3760/cma.j.issn.1673-4114.2016.06.011]
Jiazhong,Li Yongmei,Liu Yan,et al.Reasons for the abnormal 99Tcm-MDP uptake in the thoracic tissue on bone scintigraphy[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):459.[doi:10.3760/cma.j.issn.1673-4114.2016.06.011]
[8]马彦云,张辉.磁共振体素内不相干运动扩散加权成像的原理及应用进展[J].国际放射医学核医学杂志,2016,40(6):469.[doi:10.3760/cma.j.issn.1673-4114.2016.06.013]
Ma Yanyun,Zhang Hui.The basic principle and application progress of intravoxel incoherent motion imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):469.[doi:10.3760/cma.j.issn.1673-4114.2016.06.013]
[9]安淑娴,宋少莉,黄钢.放射性核素标记的凋亡显像剂的研究进展[J].国际放射医学核医学杂志,2015,39(6):470.[doi:10.3760/cma.j.issn.1673-4114.2015.06.008]
An Shuxian,Song Shaoli,Huang Gang.Recent advances in apoptosis imaging using radionuclide-labeled tracers[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):470.[doi:10.3760/cma.j.issn.1673-4114.2015.06.008]
[10]杨卫东,汪静.肿瘤核素靶向治疗新进展[J].国际放射医学核医学杂志,2015,39(1):19.[doi:10.3760/cma.j.issn.1673-4114.2015.01.006]
Yang Weidong,Wang Jing.Advance progress of radionuclide target tumor therapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):19.[doi:10.3760/cma.j.issn.1673-4114.2015.01.006]
[11]陈顺军,程兵.肿瘤细胞凋亡核素显像分子探针研究进展[J].国际放射医学核医学杂志,2016,40(2):149.[doi:10.3760/cma.j.issn.1673-4114.2016.02.013]
Chen Shunjun,Cheng Bing.Progress in molecular probes of radionuclide tumor apoptosis imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):149.[doi:10.3760/cma.j.issn.1673-4114.2016.02.013]
[12]张敬勉,赵新明,王建方,等.99Tc-亚甲基二膦酸盐与153Sm-乙二胺四亚甲基膦酸对骨侵袭和骨质溶解抑制作用的对比研究[J].国际放射医学核医学杂志,2008,32(6):321.
ZHANG Jing-mian,ZHAO Xin-ming,WANG Jian-fang,et al.The comparative study of inhibitory effects of 99Tc-methylenediphosphonate and 153Sm-ethylene diamine tetramethylene phosphonic acid on bone invasion and osteolysis[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(5):321.
[13]张欣,李亚明.99mTc标记annexin V类显像剂细胞凋亡显像在肿瘤研究中的应用及进展[J].国际放射医学核医学杂志,2006,30(4):210.
ZHANG Xin,LI Ya-ming.Application and advance of apoptosis 99mTc labelled annexin V imaging in tumor research[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(5):210.
[14]黄代娟.放射性核素标记annexin V凋亡显像在肿瘤研究中的进展[J].国际放射医学核医学杂志,2003,27(4):165.
HUANG Dai-juan.Advance of apoptosis imaging with radiolabeled annexin V in tumor research[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(5):165.
[15]林亚华,叶巧滔.FHIT基因研究进展[J].国际放射医学核医学杂志,2001,25(6):275.
LIN Ya-hua,YE Qiao-tao.Advances of FHIT gene[J].International Journal of Radiation Medicine and Nuclear Medicine,2001,25(5):275.
[16]元龚骏,聂大红,唐刚华.临床用肿瘤细胞凋亡核医学显像剂研究进展[J].国际放射医学核医学杂志,2017,41(4):271.[doi:10.3760/cma.j.issn.1673-4114.2017.04.007]
Yuan Gongjun,Nie Dahong,Tang Ganghua.Progress of nuclear medicine imaging agents for the clinical apoptosis imaging of tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2017,41(5):271.[doi:10.3760/cma.j.issn.1673-4114.2017.04.007]
[17]刘成,程竞仪,章英剑.碳离子射线诱导细胞凋亡的研究进展[J].国际放射医学核医学杂志,2018,(1):58.[doi:10.3760/cma.j.issn.1673-4114.2018.01.011]
Liu Cheng,Cheng Jingyi,Zhang Yingjian.Progress in cell apoptosis induced by carbon ion beam[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(5):58.[doi:10.3760/cma.j.issn.1673-4114.2018.01.011]