[1]李雨,Кравцов BЮ,ШантьIрь ИИ,等.切尔诺贝利核事故受照射人员生物标本数据库的建立[J].国际放射医学核医学杂志,2006,30(6):356-358.
　LI Yu,B,I,et al.The biotic sample bank of Chernobyl nuclear accident[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(6):356-358.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第6期
页码:
356-358
栏目:
放射生物学
出版日期:
1900-01-01

文章信息/Info

Title:
The biotic sample bank of Chernobyl nuclear accident
作者:
李雨1;  Кравцов BЮ2;  ШантьIрь ИИ2;  АстаФев ОМ2;  Федорцева РФ2;  Aleksanin SS2;  闵锐1;  蔡建明1
1. 200433 上海, 第二军医大学海医系放射医学教研究;
2. AU-Russia Center of Emergency and Radiation Medicine, St. Petersburg 194044, Russia
Author(s):
LI Yu1;  Кравцов BЮ2;  ШантьIрь ИИ2;  АстаФев ОМ2;  Федорцева РФ2;  Aleksanin SS2;  MIN Rui1;  CAI Jian-ming1
1. Department of Radiation Medicine in Navy Medicine Faculty, The Second Military Medical University, Shanghai 200433, China;
2. AU-Russia Center of Emergency and Radiation Medicine, St. Petersburg 194044, Russia
关键词:
事故; 辐射; 生物标本库; 切尔诺贝利
Keywords:
Accident;  radiation; Biological specimen banks; Chernobyl
分类号:
Q-34
摘要:
目的 建立一种简易的核事故受照射人员生物标本库,准备用于研究小剂量电离辐射对人体作用。方法 将血液标本固定于滤膜上加以封存,血液标本常规涂片染色保存和保存一部分头发。结果 收集1162例人体生物标本,其中958例切尔诺贝利核事故清理工作人员,46例其他核事故受照射人员,158例对照组人员,这些生物标本附有完整的信息数据。结论 建立的生物标本数据库对于更加详尽获取辐射生物效应信息、回顾性研究辐射对人类机体作用机制,具有重要的理论和实践价值。
Abstract:
Objective To built a simple and easy biologic sample bank from irradiated people in nuclear accident, for the long time research of biological effect of low dose ionization radiation on people. Methods The blood sample is fixed on a piece of filter paper rand sealed up in plastic bottle for keeping, blood sample scribble on glass lice, fixed and dyed as routine clinic examination, and still, reserve a slice of hair of the examined people. Results Having built a biologic sample bank which from 1162 human body. The samples are come from 958 liquidators of Chernobyl nuclear accident, 46 people in other nuclear accident and 158 people as control groups. It is also having much information details. Conclusions If the biologic sample bank is combined with the modern bimolecular technique, maybe have much meaningful for the theory and practice of radiobiology.

参考文献/References:

1 WHO. An overview health effect of the chemobyl accident(Sheet WHO/303). The 1lth Coordination and Planning Meeting of the WHO. Kiev:Ukraine, 2006.
2 Detours V, Wattel S, Venet D, et al. Absence of a specific radiation signature in post-Chemobyl thyroid cancers. Br J Cancer,2005, 92(8):1545-1552.
3 Krychkov VP, Chumak VV, Kosterev VV, et.al. The problem of dose for Liquidators of ChNPP Accident and the possibility of its Decision by fuzzy Sets method. Book of ANS Radiation Protection and Shielding Topical Conference, American Nuclear Society,1998. 562-567.
4 Ciampi R, Knauf JA, Kerler R, et al. Oncogenic AKAP9-BBAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. J Clin Invest, 2005,115(1):94-101.
5 Шантырь ИИ, Макарова НА, Астафъев ОМ, И ДР Методика выделения группповышенного риска утраты здоровья среди участников аварийно-восстановительных работ на ЧАЭС-С-П6: ВЦЭРМ МЧС России,2001.20.

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备注/Memo

备注/Memo:
收稿日期:2006-09-29。
基金项目:国家自然科学基金项目(30270421)
通讯作者:Кравцов ВЮ,E-mail:psn@arcerm.spb.ru
更新日期/Last Update: 1900-01-01