[1]顾爱华.CT和MR肝脏灌注成像技术及其临床应用[J].国际放射医学核医学杂志,2006,30(3):188-192.
 GU Ai-hua.CT and MR perfusion imaging of the liver:techniques and clinical applications[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(3):188-192.
点击复制

CT和MR肝脏灌注成像技术及其临床应用(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第3期
页码:
188-192
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
CT and MR perfusion imaging of the liver:techniques and clinical applications
作者:
顾爱华
200025 上海, 上海同济大学附属上海市第十人民医院放射科
Author(s):
GU Ai-hua
Department of Radiology, Shanghai Tenth People’s Hospital, Shanghai Tongji University, Shanghai 200080, China
关键词:
体层摄影术X线计算机磁共振成像灌注成像
Keywords:
Tomography X-rayscomputedMagnetic resonance imagingLiverPerfusion imaging
分类号:
R445.2
摘要:
近年来随着CT、MR功能成像研究的发展,国内外有不少学者尝试使用CT、MR肝脏灌注成像评价肝脏功能及肝脏病变的血液动力学特征。综述了近来国内外CT、MR灌注成像在肝脏评价中的应用现状,重点是图像分析方法及临床应用。
Abstract:
In recent years the functional imaging techniques of CT and MR including perfusion imaging have developed fast. Some studies are attempting to evaluate the hepatic function and the hemodynamic characteristics of the hepatic lesions by using CT or MR perfusion imaging. The purpose of this article is to review the recent studies of the applications of CT and MR perfusion imaging to the evaluation of the liver. The main topics are imaging analysis and clinical applications.

参考文献/References:

1 Axel L. Cerebral blood flow determination by rapid-sequence computed tomography:theoretical analysis. Radiology, 1980, 137:679-686.
2 Gulberg V, Haag K, Rossle M, et al. Hepatic arterial buffer response in patients with advanced cirrhosis. Hepatology, 2002,35(3):630-634.
3 Tsushima Y, Funabasama S, Sanada S, et al. Development of perfusion CT software for personal computers. Acad Radiol, 2002,9(8):922-926.
4 Annet L, Materne R, Danse E, et al. Hepatic flow parameters measured with MR imaging and Doppler US:correlations with degree of cirrhosis and portal hypertension. Radiology, 2003, 229(2):409-414.
5 Ichikawa T, Arbab AS, Araki T, et al. Perfusion MR imaging with a superparamagnetic iron oxide using T2-weighted and susceptibility-sensitive echoplanar sequences:evaluation of tumor vascularity in hepatocellular carcinoma. AJR, 1999, 173(1):207-213.
6 Materne R, Smith AM, Peeters F, et al. Assessment of hepatic perfusion parameters with dynamic MRI. Magn Reson Med, 2002,47(1):135-142.
7 Van Beers BE, Leconte I, MaternetR, et al. Hepatic perfusion parameters in chronic liver disease:dynamic CT measurements correlated with disease severity. AJR, 2001, 176(3):667-673.
8 Peters AM, Brown J, Hartnell GG, et al. Non-invasive measurement of renal blood flow with 99mTc DTPA:comparison with radiolabelled microspheres. Cardiovasc Res, 1987, 21(11):830-834.
9 Tsushima Y, Blomley MJ, Kusano S, et al. Measuring portal venous perfusion with contrast-enhanced CT:comparison of direct and indirect methods. Acad Radiol, 2002, 9(3):276-282.
10 Blomley MJ, Coulden R, Dawson P, et al. Liver perfusion studied with uhrafast CT. J Comput Assist Tomogr, 1995, 19(3):424-433.
11 Materne R, Van Beers BE, Smith AM, et al. Non-invasive quantification of liver perfusion with dynamic computed tomography and a dual-input one-compartmental model. Clin Sci, 2000, 99(6):517-525.
12 Materne R, Annet L, Dechambre S, et al. Dynamic computed tomog-raphy with low-and high-molecular-mass contrast agents to assess microvascular permeability modifications in a model of liver fibrosis. Clin Sci, 2002, 103(2):213-216.
13 Van Beers BE, Materne R, Annet L, et al. Capillarization of the sinu-soids in liver fibrosis:noninvasive assessment with contrast-enhanced MRI in the rabbit. Magn Reson Med, 2003, 49(4):692-699.
14 Peeters F, Annet L, Hermoye Let al. Inflow correction of hepatic perfusion measurements using Tl-weighted, fast gradient-echo, contrast-enhanced MRI. Magn Reson Med, 2004, 51(4):710-717.
15 Weidekamm C, Cejna M, Kramer L, et al. Effects of TIPS on liver perfusion measured by dynamic CT. Am J Roentgenol, 2005, 184(2):505-510.
16 Tsushima Y, Unno Y, Koizumi J, et al. Hepatic perfusion changes af-ter transcatheter arterial embolization (TAE) of hepatocellular car-cinoma:measurement by dynamic computed tomography(CT). Dig Dis Sci, 1998, 43(2):317-322.
17 Tsushima Y, Funabasama S, Aoki J, et al. Quantitative perfusion map of malignant liver tumors, created from dynamic computed tomography data. Acad Radiol, 2004, 11(2):215-223.
18 Totman JJ, O’gorman RL, Kane PA, et al. Comparison of the hepatic perfusion index measured with gadolinium-enhanced volumetric MRI in controls and in patients with colorectal cancer.Br J Radiol, 2005, 78(926):105-109.
19 Fuentes MA, Keith CJ, Griffiths M, et al. Hepatic haemodynamics:interrelationships between contrast enhancement and perfusion on CT and Doppler perfusion indices. Br J Radiol, 2002, 75(889):17-23.
20 Pandharipande PV, Krinsky GA, Rusinek H, et al. Perfusion imaging of the liver with time-resolved, contrast-enhanced, whole-liver MRI (abstr). In:proceedings of the 11th Meeting of the international Society for Magnetic Resonance in Medicine, 2003, 1251.
21 Rusinek H, Lee VS, Johnson G. optimal dose of Gd-DTPA in dynamic MR studies. Magn Reson Med, 2001, 46(2):312-316.
22 McKenzie CA, Plato FS, Thornhill RE, et al. T(1) fast acquisition relaxation mapping (T[1]-FARM):optimized data acquisition. J Magn Reson Imaging, 2000, 18(2):129-138.
23 Kapanen MK, Halavaara JT, Hakkinen AM. Open four-concpartment model in the measwrement of liver perfusion. Acacl Radiol, 2005, 12(12):1542-1550.

相似文献/References:

[1]周翠屏,廖俊杰,何国华,等.原发性肠系膜巨大淋巴结增生症的MSCT表现与病理对照分析[J].国际放射医学核医学杂志,2016,40(3):175.[doi:10.3760/cma.j.issn.1673-4114.2016.03.003]
 Zhou Cuiping,Liao Junjie,He Guohua,et al.Primary mesenteric Castleman disease:MSCT findings with histopathologic correlation[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):175.[doi:10.3760/cma.j.issn.1673-4114.2016.03.003]
[2]尤阳,轩昂,张杰,等.淋巴瘤患者大脑静息葡萄糖代谢改变[J].国际放射医学核医学杂志,2016,40(4):255.[doi:10.3760/cma.j.issn.1673-4114.2016.04.003]
 You Yang,Xuan Ang,Zhang Jie,et al.Changes in resting-state brain glucose metabolism in patients with lymphoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):255.[doi:10.3760/cma.j.issn.1673-4114.2016.04.003]
[3]王朋,崔邦平,代文莉,等.18F-FDG PET/CT在前列腺癌中的应用进展[J].国际放射医学核医学杂志,2016,40(4):277.[doi:10.3760/cma.j.issn.1673-4114.2016.04.008]
 Wang Peng,Cui Bangping,Dai Wenli,et al.Progress in the application of 18F-FDG PET/CT in prostate cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):277.[doi:10.3760/cma.j.issn.1673-4114.2016.04.008]
[4]李菲,黄俊星,张俊.18F-FDG PET/CT在食管癌中的临床应用[J].国际放射医学核医学杂志,2016,40(4):282.[doi:10.3760/cma.j.issn.1673-4114.2016.04.009]
 Li Fei,Huang Junxing,Zhang Jun.The clinical application of 18F-FDG PET/CT in esophageal cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):282.[doi:10.3760/cma.j.issn.1673-4114.2016.04.009]
[5]刘淑蓉,孙凯.低辐射剂量冠状动脉成像的研究进展[J].国际放射医学核医学杂志,2016,40(4):293.[doi:10.3760/cma.j.issn.1673-4114.2016.04.011]
 Liu Shurong,Sun Kai.The advances of low radiation dose coronary computed tomography angiography imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):293.[doi:10.3760/cma.j.issn.1673-4114.2016.04.011]
[6]郑雪,孙凯.双源双能量CT心肌灌注成像的研究进展[J].国际放射医学核医学杂志,2016,40(4):301.[doi:10.3760/cma.j.issn.1673-4114.2016.04.013]
 Zheng Xue,Sun Kai.Progress of dual-energy myocardial perfusion imaging by dual-source computed tomography[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):301.[doi:10.3760/cma.j.issn.1673-4114.2016.04.013]
[7]徐佳欢,孙凯.第二代双源CT大螺距模式低辐射剂量血管成像进展[J].国际放射医学核医学杂志,2016,40(5):389.[doi:10.3760/cma.j.issn.1673-4114.2016.04.011]
 Xu Jiahuan,Sun Kai.Application of high-pitch and low-dose mode using dual-source CT by computed tomography angiography[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):389.[doi:10.3760/cma.j.issn.1673-4114.2016.04.011]
[8]蔡培坤,梁辉晖,董琴,等.640层螺旋CT冠脉成像对心肌桥-壁冠状动脉的形态学量化评价及粥样硬化相关性分析[J].国际放射医学核医学杂志,2016,40(6):442.[doi:10.3760/cma.j.issn.1673-4114.2016.06.008]
 Cai Peikun,Liang Huihui,Dong Qin,et al.Quantitative evaluation of morphological characteristics and their correlation with atherosclerosis of the myocardial bridge-mural coronary artery by 640 multi-detector spiral CT[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):442.[doi:10.3760/cma.j.issn.1673-4114.2016.06.008]
[9]徐勐,张越,傅菲,等.MSCT上肢静脉直接成像技术的应用[J].国际放射医学核医学杂志,2015,39(6):462.[doi:10.3760/cma.j.issn.1673-4114.2015.06.006]
 Xu Meng,Zhang Yue,Fu Fei,et al.The application of MSCT in upper limb vein direct imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(3):462.[doi:10.3760/cma.j.issn.1673-4114.2015.06.006]
[10]安淑娴,宋少莉,黄钢.放射性核素标记的凋亡显像剂的研究进展[J].国际放射医学核医学杂志,2015,39(6):470.[doi:10.3760/cma.j.issn.1673-4114.2015.06.008]
 An Shuxian,Song Shaoli,Huang Gang.Recent advances in apoptosis imaging using radionuclide-labeled tracers[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(3):470.[doi:10.3760/cma.j.issn.1673-4114.2015.06.008]
[11]周玉祥,蓝博文,黄春榆,等.64排螺旋CT冠状动脉血管成像诊断冠状动脉-肺动脉瘘的应用价值[J].国际放射医学核医学杂志,2016,40(1):26.[doi:10.3760/cma.j.issn.1673-4114.2016.01.006]
 Zhou Yuxiang,Lan Bowen,Huang Chunyu,et al.Clinical value of coronary artery-pulmonary artery fistula revealed by 64-slice spiral CT coronary angiography[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):26.[doi:10.3760/cma.j.issn.1673-4114.2016.01.006]
[12]陈超坤,刘亮,傅飞先,等.囊性胸腺瘤和囊性畸胎瘤的影像学特征及鉴别诊断[J].国际放射医学核医学杂志,2016,40(1):31.[doi:10.3760/cma.j.issn.1673-4114.2016.01.007]
 Chen Chaokun,Liu Liang,Fu Feixian,et al.Imaging features and differential diagnosis of cystic thymoma and cystic teratoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):31.[doi:10.3760/cma.j.issn.1673-4114.2016.01.007]
[13]岳进,苏丽萍.全身MRI与PET/CT在淋巴瘤骨髓浸润诊断及预后中的作用[J].国际放射医学核医学杂志,2016,40(1):50.[doi:10.3760/cma.j.issn.1673-4114.2016.01.010]
 Yue Jin,Su Lipin.Function of whole-body MRI and PET/CT in the diagnosis and prognosis of lymphoma with bone marrow infiltration[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):50.[doi:10.3760/cma.j.issn.1673-4114.2016.01.010]
[14]张莹莹,王振光,孔艳.PET/CT显像在肺间质纤维化中的应用进展[J].国际放射医学核医学杂志,2016,40(1):55.[doi:10.3760/cma.j.issn.1673-4114.2016.01.011]
 Zhang Yingying,Wang Zhenguang,Kong Yan.Application advancement on PET/CT in pulmonary interstitial fibrosis[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):55.[doi:10.3760/cma.j.issn.1673-4114.2016.01.011]
[15]麦卫平,张永林.能谱CT成像在肺癌诊断中的应用研究进展[J].国际放射医学核医学杂志,2016,40(1):77.[doi:10.3760/cma.j.issn.1673-4114.2016.01.015]
 Mai Weiping,Zhang Yonglin.Research progress of spectral imaging in the diagnosis of lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):77.[doi:10.3760/cma.j.issn.1673-4114.2016.01.015]
[16]史文杰,孟召伟,谭建.基于Deauville标准探讨18F-FDG PET/CT在霍奇金淋巴瘤复发诊断中的应用价值[J].国际放射医学核医学杂志,2016,40(2):120.[doi:10.3760/cma.j.issn.1673-4114.2016.02.007]
 Shi Wenjie,Meng Zhaowei,Tan Jian.Value of 18F-FDG PET/CT on diagnosis of Hodgkin lymphoma recurrence using Deauville criterion[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):120.[doi:10.3760/cma.j.issn.1673-4114.2016.02.007]
[17]张巧娜,刘汉东.上颌窦上皮-肌上皮癌的CT表现一例[J].国际放射医学核医学杂志,2016,40(3):237.[doi:10.3760/cma.j.issn.1673-4114.2016.03.015]
[18]张巍,杨珂.18f正电子放射性药物生产及使用中医务人员的受照剂量研究[J].国际放射医学核医学杂志,2015,39(5):420.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 016]
 zhang wei,yang ke..the research of radiation dose of 18f-fdg to pet/ct related personnel[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(3):420.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 016]
[19]曹登敏,林美福,陈文新,等.继发性骨淋巴瘤的18F-FDG PET/CT影像学表现[J].国际放射医学核医学杂志,2016,40(6):403.[doi:10.3760/cma.j.issn.1673-4114.2016.06.001]
 Cao Dengmin,Lin Meifu,Chen Wenxin,et al.Analysis on 18F-FDG PET/CT imaging characteristics in secondary bone lymphoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):403.[doi:10.3760/cma.j.issn.1673-4114.2016.06.001]
[20]李生栩,唐明灯,林端瑜,等.18F-FDG PET/CT在胸段食管鳞癌淋巴结转移中的诊断价值[J].国际放射医学核医学杂志,2016,40(6):408.[doi:10.3760/cma.j.issn.1673-4114.2016.06.002]
 Li Shengxu,Tang Mingdeng,Lin Duanyu,et al.Value of 18F-FDG PET/CT in detecting metastatic lymph nodes of thoracic esophageal squamous cell carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):408.[doi:10.3760/cma.j.issn.1673-4114.2016.06.002]

备注/Memo

备注/Memo:
收稿日期:2005-07-21。
更新日期/Last Update: 1900-01-01