[1]古桂雄.辐射诱导发育脑细胞凋亡的分子调节[J].国际放射医学核医学杂志,2000,24(2):82-85.
 GU Gui-xiong.Influence of radiation-induced apoptosis on development brain in molecular regulation[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(2):82-85.
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辐射诱导发育脑细胞凋亡的分子调节(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第2期
页码:
82-85
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Influence of radiation-induced apoptosis on development brain in molecular regulation
作者:
古桂雄
215003 江苏 苏州, 苏州医学院附属儿童医院
Author(s):
GU Gui-xiong
Suzhou Children Hospital, Suzhou Medical College, Jiangsu Suzhou 215003, China
关键词:
辐射脑发育凋亡基因生物因子
Keywords:
radiationdevelopment brainapoptosisgenebiological factor
分类号:
Q274
摘要:
近年来辐射诱导脑细胞损伤研究表明,某些基因如即早基因、Bcl-2家族、P53热休克蛋白、AT(共济失调性毛细管扩张症)基因电脑辐射放育的细胞凋亡中发挥重要的调控作用;而神经生长因子、白细胞介素-l、肿瘤坏死因子、碱性纤维生长因子、转化生长因子等生物因子在抑制辐射诱导细胞凋亡中具有重要的保护作用。
Abstract:
An outline of current status on the influence of radiation on the development brain was given in the paper. Some genes as immediate early gene, Bcl-2 family, p53, heat shock protein and AT gene play an important regulation role in ionizing radiation-induced development brain cells apoptosis. And such biological factor as nerve growth factor, interlukin-l, tumor necrosis factor, basic fibroblast growth factor, transforming growth factor and so on have a vital protection function against ionizing radiation-induced cells apoptosis.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:1999-01-13。
作者简介:古桂雄(1954-),男,广东兴宁人,苏州医学院儿童医院主任医师,博士,主要从事发育脑保护的研究。
更新日期/Last Update: 1900-01-01