[1]张海兵,章龙珍.低剂量照射在肿瘤治疗中的应用研究进展[J].国际放射医学核医学杂志,2008,32(4):243-246.
 ZHANG Hai-bing,ZHANG Long-zhen.Advance of treatment in tumor by low-dose radiation[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(4):243-246.
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低剂量照射在肿瘤治疗中的应用研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
32
期数:
2008年第4期
页码:
243-246
栏目:
放射生物学
出版日期:
1900-01-01

文章信息/Info

Title:
Advance of treatment in tumor by low-dose radiation
作者:
张海兵1 章龙珍2
1. 313000 湖州, 浙江省湖州市中心医院放疗科;
2. 221002 徐州, 徐州医学院附属医院放疗科
Author(s):
ZHANG Hai-bing1 ZHANG Long-zhen2
1. Department of Radiation Oncology, Centrol Hospital of Huzhou, Zhejang Huzhou 313000, China;
2. Department of Radiation Oneology, Affiliated Hospital of Xuzhou Medical Colkge, Xuzhou 221002, China
关键词:
辐射剂量全身照射辐射耐受性细胞凋亡肿瘤治疗方案
Keywords:
Radiation dosageWhole.body irradiationRadiation toleranceApoptosisAntineoplatie protocols
摘要:
电离辐射生物效应与辐射剂量和剂量率有关,大、中剂量照射以损伤效应为主,低剂量照射可诱导机体的兴奋效应、适应性反应、超敏感性、旁效应等。低剂量全身照射通过诱导免疫增强效应、超敏感性、激活抗氧化酶系统及肿瘤细胞凋亡等机制具有抗肿瘤作用,降低随后较大剂量辐射诱发的肿瘤发生率。目前。低剂量照射在肿瘤防治中的应用正成为研究的热点。
Abstract:
The biological effects of ionizing irradiation is related with dose and dose-rate.Medium to large dose irradiation can induce damaging effect to biosystem.but low dose radiation may induce adaptive response,hormesis,hyper.sensitiVeness and bystander effeeL Especially experimental data suggest that the antitumor effects of immune enhancement,intrinsic hypersensitivity,activation antioxidase enzymatic system and induction of apoptosis is produced by low-dose total body irradiation.Furthermore it call decrease relative cancer risk in exposed populations.Therefore.the antitumor effect by low-dose irradiation is being widely investigated and intensively researched.

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备注/Memo

备注/Memo:
收稿日期:2008-03-02。
基金项目:国家自然科学基金资助项目(30770916)
通讯作者:章龙珍,E-mail:jsxzzlz@126.com
更新日期/Last Update: 1900-01-01