[1]张耀文,曹永珍,李进,等.基因治疗联合放射治疗恶性肿瘤[J].国际放射医学核医学杂志,2008,32(4):247-250.
　ZHANG Yao-wert,CAO Yong-zhen,LI Jin,et al.Gene therapy and radiotherapy in malignant tumor[J].International Journal of Radiation Medicine and Nuclear Medicine,2008,32(4):247-250.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
32
期数:
2008年第4期
页码:
247-250
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Gene therapy and radiotherapy in malignant tumor
作者:
张耀文1;  曹永珍1;  李进2;  王芹2
1. 300052 天津, 天津医科大学总医院放疗科;
2. 300192 天津, 中国医学科学院放射医学研究所分子核医学重点实验室
Author(s):
ZHANG Yao-wert1;  CAO Yong-zhen1;  LI Jin2;  WANG Qin2
1. Department of Radiation Oncology, General Hospital of Tianjin Medical University, Tianjin 300052, China;
2. Key Laboratory of Molecular Nuclear Medwine, Institute of Radiation Medicine, Chinese Academy of Medical Sicences, Tianjin 300192, China
关键词:
肿瘤; 基因疗法; 放射疗法
Keywords:
Tumor; Gene therapy; Radiotherapy
摘要:
肿瘤治疗是目前医学研究的重点之一,基因治疗与放射治疗方法的结合倍受重视,根据技术特点这种联合治疗方法主要有:免疫基因治疗联合放疗、直接杀伤或抑制肿瘤细胞的基因治疗联合放疗、抗肿瘤血管生成的基因治疗联合放疗以及辐射保护性基阗治疗。综述了近年来基因治疗联合放射治疗恶性肿瘤的研究现状以及可能的作用机制。
Abstract:
Tumor treatment is one of the most important fields in medical research.Nowadays, a novel method which is combined gene therapy with radiotherapy plays an important role in the field of cancer research,and mainly includes immune gene therapy combined with radiotherapy,suicide gene therapy or tumor suppressor gene therapy combined with radiotherapy,antiangiogenesis gene therapy combined with radiotherapy and protective gene therapy combined with radiotherapy based on the technical features.This review summarized the current status of combined therapies of gene therapy and radiotherapy and possible mechanism.

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备注/Memo

备注/Memo:
收稿日期:2008-01-24。
基金项目:国家自然科学基金资助项目(30770638);天津市自然科学基金资助项目(05YFJMJCl2100)
通讯作者:曹永珍,E-mail:cyz1956@hotmail.com
更新日期/Last Update: 1900-01-01