[1]黄喆敏,左传涛,管一晖.18F-氟脱氧葡萄糖的脑肿瘤PET[J].国际放射医学核医学杂志,2007,31(3):163-165,172.
 HUANG Zhe-min,ZUO Chuan-tao,GUAN Yi-hui.Non 18F-fluorodeoxyglucose PET imaging of brain tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(3):163-165,172.
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18F-氟脱氧葡萄糖的脑肿瘤PET(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第3期
页码:
163-165,172
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Non 18F-fluorodeoxyglucose PET imaging of brain tumors
作者:
黄喆敏 左传涛 管一晖
200235 上海, 上海复旦大学附属华山医院PET中心
Author(s):
HUANG Zhe-min ZUO Chuan-tao GUAN Yi-hui
Department of PET Center, Huashan Hospital, Fudan University, Shanghai 200233, China
关键词:
体层摄影术发射型计算机脑肿瘤11C-甲硫氨酸11C-胆碱18F-氟脱氧胸苷
Keywords:
Tomographyemission-computedBrain tumor11C-methionine11C-choline18F-fluorothymidine
分类号:
R814.42;R817.4
摘要:
由于大脑皮质的葡萄糖摄取相对较高,常规18F-氟脱氧葡萄糖(18F-FDG)PET对于脑肿瘤,特别是低度恶性脑肿瘤的显像有较大的局限性.近年来,各种特异性更高的放射性示踪剂如11C-甲硫氨酸(11C-MET),11C-胆碱(11C-choline),18F-氟脱氧胸苷(18F-FLT)等越来越多地应用于脑肿瘤显像.非18F-FDG的放射性示踪剂在脑肿瘤的显像中均具有脑本底摄取低、肿瘤影像对比度好、对低级别胶质瘤敏感性较高的优点,在脑肿瘤的诊断、鉴别诊断、放疗计划的制定及疗效监测等方面比18F-FDG有着明显的优势.
Abstract:
Due to the high uptake of the (18F-fluoroleoxyjlucose,18F-FDG) in brain cortex, the conventional way of PET imaging for the brain tumors has been limited, especially when the tumor is of low WHO grade. Lately, some more specific PET imaging agents (11C-methionine,11C-choline,18F-fluorothymidine, etc.) have been developed and are being applied to the PET imaging of brain tumors. The common advantages of these new agents are low background uptake, high contrast of tumor imaging and higher sensitivity for low-grade gliomas. These new agents are expected to make better application in diagnosis, differential diagnosis, planning of radiotherapy and treatment effectiveness monitering of brain tumors than 18F-FDG. This article will make a brief introduction of the application of these non-18F-FDG agents in aspects mentioned above.

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备注/Memo

备注/Memo:
收稿日期:2006-12-26。
通讯作者:管一晖,E-mail:guanyihui@hotmail.com
更新日期/Last Update: 1900-01-01