[1]刘雪辉,李洪均,于鸿煦.SPECT/CT融合显像对可疑骨转移灶的诊断效能[J].国际放射医学核医学杂志,2015,39(3):201-204.[doi:10.3760/cma.j.issn.1673-4114.2015.03.003]
　Liu Xuehui,Li Hongjun,Yu Hongxu.Diagnostic efficacy of SPECT/CT fusion imaging in assessing possible bone metastases[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(3):201-204.[doi:10.3760/cma.j.issn.1673-4114.2015.03.003]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第3期
页码:
201-204
栏目:
出版日期:
2015-05-25

文章信息/Info

Title:
Diagnostic efficacy of SPECT/CT fusion imaging in assessing possible bone metastases
作者:
刘雪辉;  李洪均;  于鸿煦
天津市第三中心医院核医学科, 天津, 300170
Author(s):
Liu Xuehui;  Li Hongjun;  Yu Hongxu
Department of Nuclear Medicine, Tianjin Third Central Hospital, Tianjin 300170, China
关键词:
肿瘤转移; 骨骼; 体层摄影术; 发射型计算机; 单光子; 体层摄影术; X线计算机
Keywords:
Neoplasm metastasis; Skeleton; Tomography;  emission-computed;  single-photon; Tomography;  X-ray computed
DOI:
10.3760/cma.j.issn.1673-4114.2015.03.003
摘要:
目的 评价SPECT/CT融合显像对可疑骨转移灶的诊断效能。方法 回顾性分析64例恶性肿瘤患者经全身骨显像发现的96个可疑骨转移病灶,对可疑病灶行同机SPECT/CT融合显像,由两名核医学医师分别对SPECT、CT及SPECT/CT融合显像进行分析并评分,以病理学结果或6个月以上复查影像学及临床随访结果作为最终确诊依据。SPECT/CT融合显像对可疑病灶的诊断效能通过受试者工作特征曲线(ROC曲线)进行评价。结果 SPECT/CT显像诊断可疑骨转移灶的灵敏度、特异度、准确率、阳性预测值和阴性预测值分别为93.1%、86.8%、90.6%、91.5%和89.2%;ROC曲线下面积:SPECT/CT融合图像为0.956,CT图像为0.897,SPECT图像为0.710。结论 SPECT/CT融合显像较SPECT及CT显像具有较高的诊断效能。
Abstract:
Objective To evaluate the diagnostic efficacy of single photon emission computed tomography/computed tomography (SPECT/CT) in assessing possible bone metastases.Methods Sixty-four patients with history of primary cancer with 96 lesions that could not be definitively diagnosed using planar scintigraphy were included in this study,and SPECT/CT was performed.SPECT,CT,and SPECT/CT images were independently interpreted and scored by two experienced nuclear medicine physicians.The final diagnosis was confirmed by the pathological results or follow-up (≥6 months).The value of additional fused images was assessed using receiver operating characteristic (ROC) analysis.Results The sensitivity,specificity,accuracy,and negative and positive predictive values for SPECT/CT imaging were 93.1%,86.8%,90.6%,91.5%,and 89.2%,respectively.The areas under the ROC curve were 0.956,0.897,and 0710 for SPECT/CT-fused images,CT images,and SPECT,respectively.Conclusion SPECT/CT fusion imaging was more accurate and valuable compared with separate sets of SPECT and CT images.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2014-11-07。
基金项目:天津市卫生局科技基金(项目编号:2013KZ12)
通讯作者:刘雪辉,Email:liuxuehuil978@tom.com
更新日期/Last Update: 1900-01-01