[1]成钊汀,朱小华.99Tcm-MIBI显像在甲状旁腺功能亢进症中的应用及进展[J].国际放射医学核医学杂志,2015,39(1):37-44.[doi:10.3760/cma.j.issn.1673-4114.2015.01.009]
 Cheng Zhaoting,Zhu Xiaohua.Application and progress of 99Tcm-MIBI scintieraphy in parathyroidism[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(1):37-44.[doi:10.3760/cma.j.issn.1673-4114.2015.01.009]
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99Tcm-MIBI显像在甲状旁腺功能亢进症中的应用及进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第1期
页码:
37-44
栏目:
出版日期:
2015-01-25

文章信息/Info

Title:
Application and progress of 99Tcm-MIBI scintieraphy in parathyroidism
作者:
成钊汀 朱小华
华中科技大学同济医学院附属同济医院核医学科, 武汉, 430030
Author(s):
Cheng Zhaoting Zhu Xiaohua
Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
关键词:
甲状旁腺功能亢进症99m锝甲氧基异丁基异腈体层摄影术发射型计算机单光子体层摄影术X线计算机
Keywords:
HyperparathyroidismTechnetium Tc 99m sestamibiTomography emission-computed single-photonTomography X-ray computed
DOI:
10.3760/cma.j.issn.1673-4114.2015.01.009
摘要:
99Tcm-MIBI SPECT对甲状旁腺功能亢进症的术前诊断有较高的灵敏度,联合超声或CT能提高诊断和定位的准确率,尤其是对异位的甲状旁腺腺瘤。随着微创甲状旁腺切除术的发展,99Tcm-MIBI SPECT/CT在术前准确定位上的价值日益凸显。甲状旁腺病灶的大小、生化指标等因素会影响99Tcm-MIBI显像的灵敏度和定位准确率。对于部分难以准确诊断和定位的甲状旁腺功能亢进症患者,11C-蛋氨酸PET/CT、四维CT、术中放射导航等是目前的研究热点和发展方向。
Abstract:
99Tcm-MIBI SPECT exhibited high sensitivity in hyperparathyroidism. Combination of ultrasound or CT can raise the diagnostic and location accuracy, especially in ectopic parathyroid adenoma. With the development of minimally invasive parathyroidectomy, the value of 99Tcm-MIBI SPECT/CT in preoperative location accuracy stands out. Many factors such as size of the gland lesions and biochemical indexes affect the sensitivity and location accuracy of 99Tcm-MIBI scintigraphy. For the negative imaging hyperparathyroidism patients, 11C-methionine PET/CT, 4D-CT and intraoperative radiation navigation is current research hot spot and development orientation.

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备注/Memo

备注/Memo:
收稿日期:2014-11-14。
基金项目:国家自然科学基金(81271600);湖北省科技计划(2011CDB551);华中科技大学同济医学院附属同济医院临床新技术、新业务基金(2010026)
通讯作者:朱小华,Email:evazhu@vip.sina.com
更新日期/Last Update: 1900-01-01