[1]陈顺军,程兵.肿瘤细胞凋亡核素显像分子探针研究进展[J].国际放射医学核医学杂志,2016,40(2):149-153.[doi:10.3760/cma.j.issn.1673-4114.2016.02.013]
 Chen Shunjun,Cheng Bing.Progress in molecular probes of radionuclide tumor apoptosis imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(2):149-153.[doi:10.3760/cma.j.issn.1673-4114.2016.02.013]
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肿瘤细胞凋亡核素显像分子探针研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
40
期数:
2016年第2期
页码:
149-153
栏目:
出版日期:
2016-03-25

文章信息/Info

Title:
Progress in molecular probes of radionuclide tumor apoptosis imaging
作者:
陈顺军 程兵
450052 郑州, 郑州大学第一附属医院核医学科
Author(s):
Chen Shunjun Cheng Bing
Department of Nuclear Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
关键词:
放射性核素显像肿瘤细胞凋亡
Keywords:
Radionuclide imagingNeolpasmsApoptosis
DOI:
10.3760/cma.j.issn.1673-4114.2016.02.013
摘要:
测定肿瘤细胞凋亡是早期评价肿瘤疗效的指标之一,放射性核素凋亡显像是目前研究最为广泛、技术最为成熟的体内肿瘤细胞凋亡分子影像学检测技术,能在活体内动态、无创地检测抗肿瘤治疗引起的细胞凋亡,有助于肿瘤疗效的早期评判和预后分析,其中特异性分子探针技术的研究开发是放射性核素凋亡显像的关键技术之一。笔者将目前有代表性的肿瘤细胞凋亡核素显像分子探针进行了总结。
Abstract:
Apoptosis is one of the important indices about the early assessment of the efficacy of tumor treatment. Among molecular imaging techniques of tumor apoptosis, radionuclide imaging is the most extensively studied and the most sensitive imaging modality, which can noninvasively and dynamically detect cell apoptosis induced by treatment in vivo, especially for efficacy of cancer therapies and prognosis of malignancies. Recently, as one of the key techniques, specific molecular probes are being developed. The representative molecular probes of the radionuclide imaging for tumor apoptosis are reviewed.

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备注/Memo

备注/Memo:
收稿日期:2015-10-10。
通讯作者:程兵,Email:chengbing@zzu.edu.cn
更新日期/Last Update: 1900-01-01