[1]苏鸣岗,谭天秩.PET肿瘤筛查:一项存在争议的检查方法[J].国际放射医学核医学杂志,2012,36(6):358-361.[doi:10.3760/cma.j.issn.1673-4114.2012.06.009]
　SU Ming-gang,TAN Tian-zhi.PET in cancer screening: a controversial imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(6):358-361.[doi:10.3760/cma.j.issn.1673-4114.2012.06.009]
点击复制

PET肿瘤筛查:一项存在争议的检查方法(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
36
期数:
2012年第6期
页码:
358-361
栏目:
PET-CT临床应用及新进展(重点专题)
出版日期:
1900-01-01

文章信息/Info

Title:
PET in cancer screening: a controversial imaging
作者:
苏鸣岗;  谭天秩
四川大学华西医院核医学科, 成都 610041
Author(s):
SU Ming-gang;  TAN Tian-zhi
Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, China
关键词:
正电子发射断层显像术; 肿瘤; 普查
Keywords:
Positron-emission tomography; Neoplasms; Mass screening
DOI:
10.3760/cma.j.issn.1673-4114.2012.06.009
摘要:
恶性肿瘤已成为目前危害人类生命健康的最严重疾病之一,早期发现及治疗是改善预后的关键。肿瘤筛查是早期发现肿瘤和癌前病变的重要途径。随着人们对肿瘤筛查手段要求的提高,PET这一高端影像学检查技术已越来越多地应用于肿瘤筛查。虽然大量数据显示PET可在人群中发现一些亚临床的恶性肿瘤,但在当代医疗实践中,PET用于肿瘤筛查依然存在很大的争议。该文旨在分析PET在目前肿瘤筛查方面的应用现状和存在的问题,以及对肿瘤筛查的意义和价值。
Abstract:
Malignancy has been one of the most dangerous threats to human health. Early diagnosis and treatment are key factors for improving prognosis. Cancer screening is an important way to detect early-stage cancer and precancerous lesion. PET has been used increasingly in cancer screening in accordance with the requirement of the public. Though a great number of data show that PET can find some subclinical malignancy, yet as a cancer screening modality, PET is still controversial in contemporary medical practice. The aim of this article is to review the application status and existing problem of PET in cancer screening, and to offer some recognition and view about cancer srceening.

参考文献/References:

[1] Schöder H,Gönen M.Screening for cancer with PET and PET/CT:potential and limitations.J Nucl Med,2007,48 suppl 1:4S-18.
[2] 房娜,王艳丽,曾磊,等.18F-FDG PET/CT在健康体检中发现恶性肿瘤的价值.齐鲁医学杂志,2012,27(1):19-21.
[3] 郭勇,田嘉禾,陈英茂,等.18F-FDG PET显像在健康查体中的意义.中国医学影像学杂志,2002,10(6):412-414.
[4] 郭勇,田嘉禾,陈英茂,等.18F-FDG PET显像在中老年人体检中的应用.中国临床医学影像杂志,2004,15(1):55-57.
[5] 张凯秀,王雪梅,李云霞.健康人群PET/CT体检显像现状分析.内蒙古医学院学报,2009,31(6):588-589.
[6] 黄健,贺晓恒.18F-FDG PET-CT显像在健康体检中的意义.南方医科大学学报,2010,30(7):1755-1757.
[7] Chen YK,Ding HJ,Su CT,et al.Application of PET and PET/CT imaging for cancer screening.Anticancer Res,2004,24(6):4103-4108.
[8] Minamimoto R,Senda M,Uno K,et al.Performance profile of FDG-PET and PET/CT for cancer screening on the basis of a Japanese Nationwide Survey.Ann Nucl Med,2007,21(9):481-498.
[9] Minamimoto R,Senda M,Terauchi T,et al.Analysis of various malignant neoplasms detected by FDG-PET cancer screening program:based on a Japanese Nationwide Survey.Ann Nucl Med,2011,25(1):45-54.
[10] Murano T,Minamimoto R,Senda M,et at.Radiation exposure and risk-benefit analysis in cancer screening using FDG-PET:results of a Japanese nationwide survey.Ann Nucl Med,2011,25(9):657-666.
[11] Hatazawa J.Cancer screening by FDG-PET:benefit or risk?.Ann Nucl Med,2011,25(9):667-668.

相似文献/References:

[1]胡伟,赵军.小胶质细胞在AD炎性机制中的作用及其常见PET显像剂的应用进展[J].国际放射医学核医学杂志,2016,40(1):44.[doi:10.3760/cma.j.issn.1673-4114.2016.01.009]
　Hu Wei,Zhao Jun.Microglia’s Alzheimer disease inflammatory mechanisms and progress of its common application in PET imaging agents[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):44.[doi:10.3760/cma.j.issn.1673-4114.2016.01.009]
[2]张莹莹,王振光,孔艳.PET/CT显像在肺间质纤维化中的应用进展[J].国际放射医学核医学杂志,2016,40(1):55.[doi:10.3760/cma.j.issn.1673-4114.2016.01.011]
　Zhang Yingying,Wang Zhenguang,Kong Yan.Application advancement on PET/CT in pulmonary interstitial fibrosis[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):55.[doi:10.3760/cma.j.issn.1673-4114.2016.01.011]
[3]李海峰,张晓军,李云钢,等.国产模块LOOP环改良法合成11C-蛋氨酸[J].国际放射医学核医学杂志,2016,40(2):106.[doi:10.3760/cma.j.issn.1673-4114.2016.02.004]
　Li Haifeng,Zhang Xiaojun,Li Yungang,et al.Synthesis of 11C-methionine on home-made module by the improved LOOP method[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):106.[doi:10.3760/cma.j.issn.1673-4114.2016.02.004]
[4]史文杰,孟召伟,谭建.基于Deauville标准探讨18F-FDG PET/CT在霍奇金淋巴瘤复发诊断中的应用价值[J].国际放射医学核医学杂志,2016,40(2):120.[doi:10.3760/cma.j.issn.1673-4114.2016.02.007]
　Shi Wenjie,Meng Zhaowei,Tan Jian.Value of 18F-FDG PET/CT on diagnosis of Hodgkin lymphoma recurrence using Deauville criterion[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):120.[doi:10.3760/cma.j.issn.1673-4114.2016.02.007]
[5]陈顺军,程兵.肿瘤细胞凋亡核素显像分子探针研究进展[J].国际放射医学核医学杂志,2016,40(2):149.[doi:10.3760/cma.j.issn.1673-4114.2016.02.013]
　Chen Shunjun,Cheng Bing.Progress in molecular probes of radionuclide tumor apoptosis imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):149.[doi:10.3760/cma.j.issn.1673-4114.2016.02.013]
[6]陈晓艳,张江虹,邵春林.STAT3与辐射敏感相关性的研究进展[J].国际放射医学核医学杂志,2016,40(3):191.[doi:10.3760/cma.j.issn.1673-4114.2016.03.007]
　Chen Xiaoyan,Jianghong,Shao Chunlin.Research progresses of correlation between STAT3 and radiosensitivity[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):191.[doi:10.3760/cma.j.issn.1673-4114.2016.03.007]
[7]李海峰,张晓军,张锦明.多巴胺转运蛋白显像剂11C-β-CFT在帕金森病中的应用研究[J].国际放射医学核医学杂志,2016,40(3):218.[doi:10.3760/cma.j.issn.1673-4114.2016.03.011]
　Li Haifeng,Zhang Xiaojun,Zhang Jinming.Review of the use of dopamine transporter imaging agent 11C-β-CFT for diagnosing Parkinson disease[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):218.[doi:10.3760/cma.j.issn.1673-4114.2016.03.011]
[8]尤阳,轩昂,张杰,等.淋巴瘤患者大脑静息葡萄糖代谢改变[J].国际放射医学核医学杂志,2016,40(4):255.[doi:10.3760/cma.j.issn.1673-4114.2016.04.003]
　You Yang,Xuan Ang,Zhang Jie,et al.Changes in resting-state brain glucose metabolism in patients with lymphoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):255.[doi:10.3760/cma.j.issn.1673-4114.2016.04.003]
[9]王朋,崔邦平,代文莉,等.18F-FDG PET/CT在前列腺癌中的应用进展[J].国际放射医学核医学杂志,2016,40(4):277.[doi:10.3760/cma.j.issn.1673-4114.2016.04.008]
　Wang Peng,Cui Bangping,Dai Wenli,et al.Progress in the application of 18F-FDG PET/CT in prostate cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):277.[doi:10.3760/cma.j.issn.1673-4114.2016.04.008]
[10]李菲,黄俊星,张俊.18F-FDG PET/CT在食管癌中的临床应用[J].国际放射医学核医学杂志,2016,40(4):282.[doi:10.3760/cma.j.issn.1673-4114.2016.04.009]
　Li Fei,Huang Junxing,Zhang Jun.The clinical application of 18F-FDG PET/CT in esophageal cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):282.[doi:10.3760/cma.j.issn.1673-4114.2016.04.009]
[11]何燕,苏晋,郑晓霞,等.P-糖蛋白抑制剂在PET显像中的应用研究[J].国际放射医学核医学杂志,2016,40(1):1.[doi:10.3760/cma.j.issn.1673-4114.2016.01.001]
　He Yan,Su Jin,ZhengXiaoxia,et al.Developing P-glycoprotein inhibitor marked by PET[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):1.[doi:10.3760/cma.j.issn.1673-4114.2016.01.001]
[12]许飞,刘建军,黄钢,等.PET乏氧显像在预测肿瘤乏氧及指导临床治疗中的应用进展[J].国际放射医学核医学杂志,2016,40(1):35.[doi:10.3760/cma.j.issn.1673-4114.2016.01.008]
　Xu Fei,Liu Jianjun,Huang Gang,et al.The application of hypoxia imaging with PET in predicting tumor hypoxia and guiding clinical therapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):35.[doi:10.3760/cma.j.issn.1673-4114.2016.01.008]
[13]陆东燕,侯莎莎,丁恩慈,等.结核性与恶性腹膜弥漫性病变的18F-FDG PET/CT影像特征分析[J].国际放射医学核医学杂志,2014,38(6):398.[doi:10.3760/cma.j.issn.1673-4114.2014.06.012]
　Lu Dong-yan,Hou Sha-sha,Ding En-ci,et al.Analysis of 18F-FDG PET/CT imaging features of tuberculous and cancerous diffuse peritoneal lesions[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(6):398.[doi:10.3760/cma.j.issn.1673-4114.2014.06.012]
[14]刘春利,李毅红.18F-FDG PET/CT在原发灶不明的脑转移瘤中的诊断价值[J].国际放射医学核医学杂志,2013,37(2):92.[doi:10.3760/cma.j.issn.1673-4114.2013.02.008]
　LIU Chun-li,LI Yi-hong.The value of 18F-FDG PET/CT in diagnosing brain metastases from unknown primary tumor[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):92.[doi:10.3760/cma.j.issn.1673-4114.2013.02.008]
[15]王胜军,杨卫东,赵小虎,等.18F-FDG PET/CT诊断多发癌的价值[J].国际放射医学核医学杂志,2013,37(2):96.[doi:10.3760/cma.j.issn.1673-4114.2013.02.009]
　WANG Sheng-jun,YANG Wei-dong,ZHAO Xiao-hu,et al.Value of 18F-FDG PET/CT in the diagnosis of multiple primary malignant neoplasms[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):96.[doi:10.3760/cma.j.issn.1673-4114.2013.02.009]
[16]唐宇辉,陈跃.PET/CT在儿科恶性肿瘤中的应用进展[J].国际放射医学核医学杂志,2013,37(2):107.[doi:10.3760/cma.j.issn.1673-4114.2013.02.012]
　TANG Yu-hui,CHEN Yue.The progression of PET/CT in pediatric malignant tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):107.[doi:10.3760/cma.j.issn.1673-4114.2013.02.012]
[17]孙爱君,任茜,刘健,等.11C-乙酸盐PET和PET/CT在肿瘤显像中的应用[J].国际放射医学核医学杂志,2013,37(4):243.[doi:10.3760/cma.j.issn.1673-4114.2013.04.013]
　SUN Ai-jun,REN Qian,LIU Jian,et al.The application of 11C-acetate PET and PET-CT for tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):243.[doi:10.3760/cma.j.issn.1673-4114.2013.04.013]
[18]辛军,赵周社,李红,等.自适应统计迭代重建技术在PET/CT全身扫描中的应用[J].国际放射医学核医学杂志,2013,37(5):279.[doi:10.3760/cma.j.issn.1673-4114.2013.05.007]
　XIN Jun,ZHAO Zhou-she,LI Hong,et al.Adaptive statistical iterative reconstruction technology in the application of PET/CT whole body scans[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):279.[doi:10.3760/cma.j.issn.1673-4114.2013.05.007]
[19]王玉婷,黄钢,蒋瑾,等.18F-FDG PET用于肿瘤治疗疗效评价的meta分析进展[J].国际放射医学核医学杂志,2012,36(6):334.[doi:10.3760/cma.j.issn.1673-4114.2012.06.004]
　WANG Yu-ting,HUANG Gang,JIANG Jin,et al.Tumor response monitoring by 18F-FDG PET: updated review of meta-analyses[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(6):334.[doi:10.3760/cma.j.issn.1673-4114.2012.06.004]
[20]江茂情,吴华.18F-FDG和18F-FLT PET-CT在肿瘤非手术治疗早期疗效评价中的应用[J].国际放射医学核医学杂志,2012,36(6):339.[doi:10.3760/cma.j.issn.1673-4114.2012.06.005]
　JIANG Mao-qing,WU Hua.18F-FDG and 18F-FLT PET-CT in evaluation of the early response of malignant tumors after different therapies[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(6):339.[doi:10.3760/cma.j.issn.1673-4114.2012.06.005]

备注/Memo

备注/Memo:
收稿日期:2012-09-13。
通讯作者:谭天秩(Email:ttianzhi1931@163.com)
更新日期/Last Update: 1900-01-01