[1]辛军,赵周社,李红,等.自适应统计迭代重建技术在PET/CT全身扫描中的应用[J].国际放射医学核医学杂志,2013,37(5):279-282.[doi:10.3760/cma.j.issn.1673-4114.2013.05.007]
　XIN Jun,ZHAO Zhou-she,LI Hong,et al.Adaptive statistical iterative reconstruction technology in the application of PET/CT whole body scans[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(5):279-282.[doi:10.3760/cma.j.issn.1673-4114.2013.05.007]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
37
期数:
2013年第5期
页码:
279-282
栏目:
论著
出版日期:
2013-09-25

文章信息/Info

Title:
Adaptive statistical iterative reconstruction technology in the application of PET/CT whole body scans
作者:
辛军;  赵周社;  李红;  陆喆;  吴文凯;  郭启勇
110004 沈阳, 中国医科大学附属盛京医院放射科
Author(s):
XIN Jun;  ZHAO Zhou-she;  LI Hong;  LU Zhe;  WU Wen-kai;  GUO Qi-yong
Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China
关键词:
肿瘤; 正电子发射断层显像术; 体层摄影术; X线计算机; 自适应统计迭代重建
Keywords:
Neoplasms; Position-emission tomography; Tomography;  X-ray; Adaptive statistical iterative reconstruction
DOI:
10.3760/cma.j.issn.1673-4114.2013.05.007
摘要:
目的 采用自适应统计迭代重建(ASiR)技术提高PET/CT全身扫描低剂量CT的图像质量。方法 采用CT性能模型测量CT值准确度和噪声,对模型进行两次扫描,扫描条件分别为:120 kV、120 mA和120 kV、300 mA。另随机选取行PET/CT扫描的受检者30例,按体重静脉注射18F-FDG 3.70 MBq,PET/CT全身扫描条件为:PET采用三维＋飞行时间＋点扩展函数重建技术,1.5 min/床位;CT采用螺旋扫描,120 kV,自动曝光控制技术(30~210 mA,噪声指数25)。模型图像和患者全身扫描CT图像分别按照常规方法和40% ASiR方法进行重建。结果 模型和临床研究结果表明,ASiR方法获得的模型CT值标准差较常规CT图像重建方法降低了33.0%(t=27.76,P<0.01),正常组织(脑、肺、纵隔、肝脏和椎体)和病灶(脑、肺、纵隔、肝脏和椎体)CT值标准差平均分别降低了21.08%(t=23.35,P<0.01)和24.43%(t=16.15,P<0.01),而肝脏正常组织和肝脏病灶分别降低了51.33%(t=34.21,P<0.01)和49.54%(t=15.21,P<0.01)。结论 采用ASiR技术明显降低了PET/CT全身扫描低剂量CT图像的噪音,提高了CT图像质量,使其适用于定量分析研究和临床应用。
Abstract:
Objective To improve image quality of low dose CT in whole body PET/CT using adaptive statistical iterative reconstruction (ASiR) technology.Methods Twice CT scans were performed with GE water model, scan parameters were:120 kV, 120 and 300 mA respectively.In addition, 30 subjects treated with PET/CT were selected randomly, whole body PET/CT were performed after 18F-FDG injection of 3.70 MBq/kg, Sharp IR＋time of flight+VUE Point HD technology were used for 1.5 min/bed in PET; CT of spiral scan was performed under 120 kV using automatic exposure control technology (30-210 mA, noise index 25).Model and patients whole body CT images were reconstructed with conventional and 40% ASiR methods respectively, and the CT attenuation value and noise index were measured.Results Research of model and clinical showed that standard deviation of ASiR method in model CT was 33.0% lower than the conventional CT reconstruction method (t=27.76, P<0.01), standard deviation of CT in normal tissues (brain, lung, mediastinum, liver and vertebral body)and lesions (brain, lung, mediastinum, liver and vertebral body) reduced by 21.08% (t=23.35, P<0.01) and 24.43% (t=16.15, P<0.01) respectively, especially for normal liver tissue and liver lesions, standard deviations of CT were reduced by 51.33% (t=34.21, P<0.0) and 49.54% (t=15.21, P<0.01) respectively.Conclusion ASiR reconstruction method was significantly reduced the noise of low dose CT image and improved the quality of CT image in whole body PET/CT, which seems more suitable for quantitative analysis and clinical applications.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2013-02-24。
通讯作者:辛军,Email:xinj@vip.sina.com.cn
更新日期/Last Update: 1900-01-01