[1]宋少莉,黄钢.18F-氟脱氧葡萄糖PET监测实体瘤放化疗疗效的应用进展[J].国际放射医学核医学杂志,2007,31(5):284-288.
 SONG Shao-Li,HUANG Gang.The development of monitoring chemotherapy and radiotherapy of solid tumor by 18F-fluorodeoxyglucose PET[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(5):284-288.
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18F-氟脱氧葡萄糖PET监测实体瘤放化疗疗效的应用进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第5期
页码:
284-288
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The development of monitoring chemotherapy and radiotherapy of solid tumor by 18F-fluorodeoxyglucose PET
作者:
宋少莉1 黄钢2
1. 200127 上海, 上海交通大学医学院附属仁济医院核医学科PET-CT中心;
2. 200127 上海, 上海交通大学临床核医学研究所
Author(s):
SONG Shao-Li1 HUANG Gang2
1. Department of PET-CT Center, School of Medicine, Shanghai JiaoTong University Shanghai. 200127, China;
2. Department of Nuclear Medicine, RenJi Hospital, School of Medicine, ShangHai JiaoTong University, Shanghai 200127, China
关键词:
体层摄影术发射型计算机氟脱氧葡萄糖F18肿瘤药物疗法放射疗法预后
Keywords:
Tomograpyemission-computedFluorodeoxyglucose F18NeoplasmsDurg therapyRadiotherapyPrognosis
分类号:
R817.4
摘要:
利用18F-氟脱氧葡萄糖(18F-FDG)PET监测肿瘤放疗或化疗的疗效以及区分残余或复发病灶已广泛用于临床.18F-FDG PET定量分析肿瘤在治疗开始时的变化可以预测肿瘤对治疗的反应性及患者的预后,并可根据肿瘤的反应性调整治疗方案.利用18F-FDG PET早期预测肿瘤对放、化疗的反应性,在个体化治疗方案的制定、减少无效治疗所带来的副作用等方面有着巨大的潜能.
Abstract:
18F-fluorodeoxyglucose (18F-FDG) PET imaging monitoring tumor response in patients undergoing ehemo-and radiotherapy and differentiation residual or recurrent viable tumor and therapy-induced fibrosis or scar tissue has been documented for various solid tumors. Furthermore, there are now several reporis suggesting that quantitative assessment of therapy-induced changes in tumor 18F-FDG uptake may allow prediction of tumor response and patient outcome very early in the course of therapy. In nonresponding patients, trcatnlent may be adjusted according to the individual chemo-and radiosensitivity of the tumor tissue. Early prediction of tumor response to ehenlotherapy and radiotherapy by 18F-FDG PET has enormous potential to "personalize" treatment and to reduce the side-effects and costs of ineffective therapy.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2007-01-26。
通讯作者:黄铜(E-mail:huang2802@163.com)
更新日期/Last Update: 1900-01-01