[1]朱苏雨,胡炳强.PET-CT用于肿瘤精确放疗靶区勾画的困惑[J].国际放射医学核医学杂志,2007,31(4):217-221.
 ZHU Su-yu,HU Bing-qiang.The dilemma of the target delineation with PET-CT in the radiotherapy planning for malignant tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(4):217-221.
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PET-CT用于肿瘤精确放疗靶区勾画的困惑(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第4期
页码:
217-221
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The dilemma of the target delineation with PET-CT in the radiotherapy planning for malignant tumors
作者:
朱苏雨 胡炳强
410013 长沙, 湖南省肿瘤医院放疗科
Author(s):
ZHU Su-yu HU Bing-qiang
Department of Radiation Oncology, The Hunan Procince Tumor Hospital, Changsha 410013, China
关键词:
体层摄影术发射型计算机体层摄影术X线计算机放射治疗计划计算机辅助
Keywords:
Tomography emission-computedTomography X-ray computedRadiotherapy planning computer-assisted
分类号:
R814.42;R817.4
摘要:
PET-CT用于精确放疗靶区勾画时,存在诸多困惑。谁来勾画靶区?差异可能来自哪些方面?究竟取多大标准化摄取值区分肿瘤和正常组织最适宜?当局部PET和CT显示肿瘤范围不一致时,靶区应当怎样确定?当区域淋巴结或远隔部位PET阳性而CT阴性或相反时,靶区的选择当作何种取舍?在目前阶段,这些问题尚未达成统一的共识,有待更进一步的关于影像和与之相匹配的病理标本相关性研究,而且需要更多远期临床增益结果来反证靶区勾画原则的可行性。
Abstract:
Questions are currently still not clearly conclusively answered, when contouring target with PET/CT in the radiotherapy planning. Who needs to contour the PET volume, the radiation oncologist or the nuclear medicine physician? Which factors will contribute to the increase of the inter-observer variability between them? What should be taken as the optimal SUV threshold to demarcate malignant tumors from the benign tissue? When the PET volume is not in accordance with the CT finding in the local area, which part should be contoured as the target? When PET positive while CT negative or PET negative while CT positive were shown in the regional lymph node draining area or in the remote region, in which way the target could be decided and selected? Further study concerning the corresponding relationship between PET-CT and its registered pathological specimen are needed. The long-term clinical results of increased therapeutic ratio will finally verify the applicability of the guideline to contour the target with PET-CT in the radiotherapy planning.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2006-12-24。
通讯作者:朱苏雨(E-mail:suyuzhu@yahoo.com)
更新日期/Last Update: 1900-01-01