[1]张文学,姜炜,吕仲虹,等.常规放疗结合后程立体定向放射治疗老年非小细胞肺癌患者的预后分析[J].国际放射医学核医学杂志,2007,31(2):125-127.
 ZHANG Wen-xue,JIANG Wei,LV Zhong-hong,et al.Prognostics analysis of common radiotherapy combined stereotactic radiotherapy for non-small cell lung cancer of old patients[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(2):125-127.
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常规放疗结合后程立体定向放射治疗老年非小细胞肺癌患者的预后分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第2期
页码:
125-127
栏目:
临床放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Prognostics analysis of common radiotherapy combined stereotactic radiotherapy for non-small cell lung cancer of old patients
作者:
张文学1 姜炜1 吕仲虹2 曹永珍2
1. 300060 天津, 天津市环湖医院放疗科;
2. 300052 天津, 天津医科大学总医院放疗科
Author(s):
ZHANG Wen-xue1 JIANG Wei1 LV Zhong-hong2 CAO Yong-zhen2
1. Department of Radiotherapy, Tianjin Huanhu Hospital, Tianjin 300060, China;
2. Department of Radiotherapy, General Hospital of Tianjin Medical University, Tianjin 300052, China
关键词:
非小细胞肺立体定向放射治疗老年人预后
Keywords:
Cancer non-small cell lungStereotactic radiotherapyAgedPrognostic factors
分类号:
R730.55
摘要:
目的 观察老年非小细胞肺癌立体定向放疗疗效,并探讨其预后因子。方法 128例老年非小细胞肺癌患者行常规放疗结合立体定向放疗,定期随访。结果 全组患者1年生存率65.72%,单因素分析表明肿瘤体积、肿瘤剂量、卡氏评分影响近期结果,多因素分析仅肿瘤体积和肿瘤剂量为近期疗效预后因子,与生存期有关的预后因素为近期疗效、肿瘤剂量、临床分期。结论 立体定向放疗可延长生存时间,对Ⅲ期患者,肿瘤剂量提高至72Gy是安全的。
Abstract:
Objective To observe the effect of stereotactic radiotherapy (SRT) for non-small cell lung cancer(NSCLC) of old patients. Method 128 NSCLC old patients receive common radiotherapy and SRT. The results was followed. Results 1-year survival rate is 65.72% for all patients on univariate analysis radiation dose,tumor volume, Karnofsky performance status (KPS) are significantly associated with first follow-up response(FFR). On multivariate analysis only the first two are significant. Prognostic factors of survival time are FFR, tumor dose and clinical stage. Conclusions SRT can significantly raise survival time expecially for phase Ⅲ patients. The dose 72 Gy for NSCLC old patients is safe.

参考文献/References:

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2 Etiz D, Marks LB, Zhou SM, et al. Influnce of tumor volume on survival in patients irradiation for non-small cell lung cancer. Int J Radiat Oncol Biol Phys, 2002, 53(4):835-846.
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备注/Memo

备注/Memo:
收稿日期:2006-08-14。
通讯作者:张文学(E-mail:fortunator5658@yahoo.com.cn)
更新日期/Last Update: 1900-01-01