[1]秦阳华,韩玲.辐射诱导旁效应研究进展[J].国际放射医学核医学杂志,2004,28(5):234-236.
 QIN Yang-hua,HAN Ling.Progress of radiation-induced bystander effect[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(5):234-236.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
28
期数:
2004年第5期
页码:
234-236
栏目:
放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Progress of radiation-induced bystander effect
作者:
秦阳华 韩玲
200433 上海, 第二军医大学海医系放射医学教研室
Author(s):
QIN Yang-hua HAN Ling
Department of Radiation Medicine, Navy medicine Faculty, the Second Military Medical University, Shanghai 200433, China
关键词:
电离辐射旁效应细胞间活性氧间隙连接一氧化氮
Keywords:
ionizing radiationbystander responsereactive oxygen speciesgap-junction intercellular communicationnitric oxide
分类号:
R730.231.2
摘要:
随着人们对低剂量辐射后发生的间接和延迟效应(如突变、基因不稳定性)的重视,以及新的高效工具(如单细胞微束和先进的培养系统)的应用,过去的十几年对辐射诱导旁效应的产生机制有了许多新的认识和发现。辐射诱导旁效应是受基因调控,由细胞间信号传递途径中介产生的。
Abstract:
With the increased awareness of the contribution of indirect and delayed effects (such as mutation, genomic instability) to cellular outcomes after low-dose exposures, and the availability of tools (such as the microbeam and advanced cell culture systems), many new discoveries about radiation-induced bystander effect has been achieved in the past decade. Evidence accumulated has indicated that radiation-induced bystander effect is regulated by special genes, and mediated by intercellual signal transmission pathway.

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备注/Memo

备注/Memo:
收稿日期:2004-05-08。
更新日期/Last Update: 1900-01-01