参考文献/References:
[1] Fletcher L, Cheng Y, Muschel RJ. Abolishment of the Tyr-15 inhibitory phosphorylation site on cdc2 reduces the radiation-induced G(2) delay, revealing a potential checkpoint in early[J]. Cancer Res, 2002, 62(1):241-250.
[2] Luo Y, Chen Z, Han EK, et al. Blocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanism[J]. Neoplasia, 2001, 3(5):411-419.
[3] Jackson JR, Roshak A, Winkler JD, et al. An indolocarbazole inhibitor of human checkpoint kinase (Chkl) abrogates cell cycle arrest caused by DNA damage[J]. Cancer Res, 2000, 60(3):566-572.
[4] Ding Z, Parchment RE, LoRusso PM, et al. The investigational new drug XK469 induces G(2)-M cell cycle arrest by p53-dependent and -independent pathways[J]. Clin Cancer Res, 2001, 7(11):3336-3342.
[5] Hu BC, Wang X, Wang Y, et al. The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway[J]. Biol Chem, 2001, 276(21):17693-17698.
[6] Oe T, Nakajo N, Katsuragi Y, et al. Cytoplasmic occurrence of the Chk1/Cdc25 pathway and regulation of Chk1 in Xenopus oocytes[J]. Dev Biol, 2001, 229(1):250-261.
[7] Atsushi H, Kong YY, Shuhei M, et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2[J]. Science, 2000, 287:1824-1827.
[8] Robert SW, Shuhei M, Stephen JE, et al. Husl acts upstream of chk1 in a mammalian DNA damage response pathway[J]. Current Biol, 2002, 12(1):73-77.
[9] Matsui F, Tsuchida Y, Keng PC. Effects of p53 mutations on cellular sensitivity to ionizing radiation[J]. Am J Clin Oncol, 2001, 24(5):486-490.
[10] Taylor WR, Atark GR, Galante J, et al. p130/E2F4 binds to and represses the cdc2 promoter in response to p53[J]. Biol Chem, 2001, 276(3):1998-2006.
[11] Jin S, Antinore MJ, Lung FD, et al. The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression[J]. Biol Chem, 2000, 275(22):16602-16608.
[12] Lee SL, Tian Hui, Faje AT, et al. Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways[J]. Neoplasia, 2002, 4(2):171-180.
[13] Gottifredi V, Karni SO, Shieh SS, et al. p53 down-regnlates CHK1 through p21 and the retinoblastoma protein[J]. Mol Cell Biol, 2001, 21(4):1066-1076.
相似文献/References:
[1]任越,张慧芳,胡波,等.电离辐射诱导小鼠骨电子顺磁共振信号检测的影响因素[J].国际放射医学核医学杂志,2015,39(5):371.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 004]
ren yue,zhang huifang,hu bo,et al.influencing factors of detection on ionizing radiation-induced electron paramagnetic resonance signal in bones[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(6):371.[doi:10. 3760 / cma. j. issn. 1673-4114. 2015. 05. 004]
[2]王平,关华顺,吕玉民.外周血核基因表达评价辐射生物剂量方法研究进展[J].国际放射医学核医学杂志,2014,38(6):416.[doi:10.3760/cma.j.issn.1673-4114.2014.06.016]
Wang Ping,Guan Hua-shun,Lyu Yu-min.Advances of nuclear gene expression signatures in peripheral blood for irradiation biodose estimation[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(6):416.[doi:10.3760/cma.j.issn.1673-4114.2014.06.016]
[3]徐畅,王彦,杜利清,等.shRNA干扰沉默Net1基因对电离辐射损伤反应的影响[J].国际放射医学核医学杂志,2013,37(3):135.[doi:10.3760/cma.j.issn.1673-4114.2013.03.002]
XU Chang,WANG Yan,DU Li-qing,et al.The effects of short hairpin RNA-mediated silencing Net1 on ionizing radiation-induced damage responses[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):135.[doi:10.3760/cma.j.issn.1673-4114.2013.03.002]
[4]刘忠超,张文艺,焦玲.辐射引起的电子自旋共振信号在回顾剂量学中的应用[J].国际放射医学核医学杂志,2013,37(5):322.[doi:10.3760/cma.j.issn.1673-4114.2013.05.016]
LIU Zhong-chao,ZHANG Wen-yi,JIAO Ling.The application of radiation-induced free radicals signals in retrospective dosimetry[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(6):322.[doi:10.3760/cma.j.issn.1673-4114.2013.05.016]
[5]陈凤,涂彧.电离辐射诱导旁效应的研究现状[J].国际放射医学核医学杂志,2009,33(6):364.[doi:10.3760/cma.j.issn.1673-4114.2009.06.015]
CHEN Feng,TU Yu.Bystander effect induced by ionizing radiation and its application[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(6):364.[doi:10.3760/cma.j.issn.1673-4114.2009.06.015]
[6]肖瑶,韩玲.电离辐射诱导旁效应的研究现状[J].国际放射医学核医学杂志,2007,31(5):303.
XIAO Yao,HAN Ling.Recent study of ionizing radiation-induced bystander effects[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(6):303.
[7]李智恒,李雨.C57小鼠受照后胸腺细胞基因表达谱的变化[J].国际放射医学核医学杂志,2007,31(4):240.
LI Zhi-heng,LI Yu.Profiling of differentially expressed genes induced by ionizing radiation in thymus cells of C57 mice[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(6):240.
[8]由莉,赵永成.γ-H2AX分析及其在监测电离辐射所致DNA双链断裂中的应用前景[J].国际放射医学核医学杂志,2006,30(1):50.
YOU Li,ZHAO Yong-cheng.γ-H2AX assay and its prospect of detecting DNA double-strand breaks caused by ionizing radiation[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(6):50.
[9]刘强,姜恩海,李进,等.SCGE作为辐射生物剂量计的可行性研究[J].国际放射医学核医学杂志,2005,29(3):126.
LIU Qiang,JIANG En-hai,LI Jin,et al.Study on the possibility of SCGE as radiation biological dosimeter[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(6):126.
[10]高荣莲,陈肖华.星形胶质细胞的电离辐射损伤及修复作用[J].国际放射医学核医学杂志,2004,28(1):37.
GAO Rong-lian,CHEN Xiao-hua.Injury and repair of astrocyte after ionizing radiation[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(6):37.
[11]刘光伟,龚守良.电离辐射诱导的细胞G2期阻滞[J].国际放射医学核医学杂志,2002,26(4):180.
LIU Guang-wei,GONG Shou-liang.G2 phase arrest of cell cycle induced by ionizing radiation[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(6):180.