[1]陆东燕,侯莎莎,丁恩慈,等.结核性与恶性腹膜弥漫性病变的18F-FDG PET/CT影像特征分析[J].国际放射医学核医学杂志,2014,38(6):398-402.[doi:10.3760/cma.j.issn.1673-4114.2014.06.012]
　Lu Dong-yan,Hou Sha-sha,Ding En-ci,et al.Analysis of 18F-FDG PET/CT imaging features of tuberculous and cancerous diffuse peritoneal lesions[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(6):398-402.[doi:10.3760/cma.j.issn.1673-4114.2014.06.012]
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结核性与恶性腹膜弥漫性病变的18F-FDG PET/CT影像特征分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
38
期数:
2014年第6期
页码:
398-402
栏目:
出版日期:
2014-11-25

文章信息/Info

Title:
Analysis of 18F-FDG PET/CT imaging features of tuberculous and cancerous diffuse peritoneal lesions
作者:
陆东燕;  侯莎莎;  丁恩慈;  赵炎;  沈婕
天津市第一中心医院核医学科, 300192
Author(s):
Lu Dong-yan;  Hou Sha-sha;  Ding En-ci;  Zhao Yan;  Shen Jie
Department of Nuclear Medicine, Tianjin First Center Hospital, Tianjin 300192, China
关键词:
腹膜; 肿瘤; 结核; 正电子发射断层显像术; 体层摄影术; X线计算机; 脱氧葡萄糖F18
Keywords:
Peritoneum; Neoplasms; Tuberculosis; Positron-emission tomography; Tomography; X-ray computed; Fluorodeoxyglucose F18
DOI:
10.3760/cma.j.issn.1673-4114.2014.06.012
摘要:
目的 分析结核性与恶性腹膜弥漫性病变的18F-FDG PET/CT表现,探讨PET/CT的诊断及鉴别诊断价值。方法 回顾性对比分析经病理和(或)临床证实的10例结核性腹膜炎、29例恶性腹膜病变(包括13例原发性腹膜浆液性乳头状腺癌、16例腹膜转移癌)的18F-FDG PET/CT表现。观察和记录指标:(1)壁腹膜、大网膜、肠系膜的受累情况;(2)腹腔积液情况;(3)淋巴结改变;(4)其他脏器伴随征象。对结核组与恶性组的受累腹膜18F-FDG代谢程度、腹腔积液密度及18F-FDG浓聚程度差异行两样本t检验。结果 结核性腹膜炎多为壁腹膜弥漫均匀增厚伴大网膜及肠系膜"污迹样"改变,18F-FDG分布较均匀;恶性腹膜病变多为壁腹膜、大网膜及肠系膜明显不规则增厚,呈多发结节状及饼状改变,18F-FDG分布不均匀。两组受累腹膜18F-FDG代谢均增高,结核性腹膜炎SUVmax为12.74±9.75,恶性腹膜病变SUVmax为12.45±7.40,两者之间的差异无统计学意义(t=0.099,P>0.05).恶性腹膜病变患者腹腔积液密度低于结核性腹膜炎患者,恶性腹膜病变患者的CT值为(11.34±3.55)HU、结核性腹膜炎患者的CT值为(14.4±2.37)HU,两者之间的差异有统计学意义(t=2.53,P<0.05);腹腔积液18F-FDG浓聚程度高于结核性腹膜炎患者,恶性腹膜病变患者SUVmax为2.10±0.65、结核性腹膜炎患者SUVmax为1.61±0.35,两者之间的差异有统计学意义(t=-2.278,P<0.05);恶性腹膜病变患者T/NT为0.77±0.18、结核性腹膜炎患者T/NT为0.58±0.12,两者之间的差异有统计学意义(t=-3.084,P<0.05).结论 18F-FDG PET/CT显像可同时显示腹膜病变的形态学和功能代谢改变,并全面显示其他脏器的伴随征象,综合分析其特征,有助于提高病变的诊断准确率。
Abstract:
Objective To analysis the 18F-FDG PET/CT features of tuberculous and cancerous diffuse peritoneal lesions and evaluate the value of 18F-FDG PET/CT in diagnosing and differentiating the lesions.Methods The 18F-FDG PET/CT features of 10 tuberculous peritonitis,13 primary serous papillary carcinoma of the peritoneum and 16 peritoneal metastases were retrospectively reviewed,which had been confirmed by clinic and/or histopathology.Four indicators were observed and graded: (1)18F-FDG PET/CT features of parietal peritoneum,greater omentum and mesentery; (2)features of ascites; (3)enlargement of lymph nodes; (4)accompanying signs of other organs.Two sample t test was used to differentiate the 18F-FDG uptake of peritoneal lesions,the density and 18F-FDG concentration of ascites between tuberculous peritonitis and cancerous peritonitis.Results The typical 18F-FDG PET/CT features of tuberculous peritonitis was uniformity thickening of parietal peritoneum,mesenteric and omental stains like change,widely and even distribution of the peritoneal 18F-FDG,while the cancerous peritonitis was obvious uneven thickening of parietal peritoneum,mesenteric and omental nodules and pie-shape changes,uneven distribution of the peritoneal 18F-FDG.The 18F-FDG uptake was increased in all peritoneal lesions,and there are no significant difference between the tuberculous group (SUVmax=12.74±9.75)and the cancerous group (SUVmax=12.45 ±7.40)(t=0.099,P>0.05).The density of malignant ascites[CTavg=(11.34±3.55)HU] was obvious lower than tuberculous ascites[CTavg=(14.4±2.37)HU] (t=2.5,P<0.05).The 18F-FDG concentration in malignant ascites (SUVmax=2.10 ±0.65,T/NT=0.77 ±0.18)was obvious higher than tuberculous ascites (SUVmax=1.61±0.35,T/NT=0.58±0.12)(t=-2.278,-3.084,both P<0.05).Conclusion The 18F-FDG PET/CT imaging can show the morphology and metabolic changes of peritoneal lesions,and fully display the lesions in the whole body.It is important to analyze 18F-FDG PET/CT features of disuse peritoneal lesions in order to improve the accuracy of diagnosing the diffuse peritoneal lesions.

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备注/Memo

备注/Memo:
收稿日期:2014-10-21。
通讯作者:沈婕(Email:ludongyan1126@163.com)
更新日期/Last Update: 1900-01-01