[1]张一秋,石洪成.肝细胞癌肿瘤新生血管影像学评价的研究进展[J].国际放射医学核医学杂志,2013,37(1):60-63.[doi:10.3760/cma.j.issn.1673-4114.2013.01.015]
 ZHANG Yi-qiu,SHI Hong-cheng.Advances in assessment of imaging examination for tumor neoangiogenesis induced by hepatocellular carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2013,37(1):60-63.[doi:10.3760/cma.j.issn.1673-4114.2013.01.015]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
37
期数:
2013年第1期
页码:
60-63
栏目:
综述
出版日期:
2013-01-25

文章信息/Info

Title:
Advances in assessment of imaging examination for tumor neoangiogenesis induced by hepatocellular carcinoma
作者:
张一秋 石洪成
复旦大学附属中山医院核医学科, 上海, 200032
Author(s):
ZHANG Yi-qiu SHI Hong-cheng
Department of Nuclear Medicine, Zhongshan Hospital, Fu-dan University, Shanghai 200032, China
关键词:
肝细胞新生血管化病理性体层摄影术X线计算机磁共振成像放射性核素显像
Keywords:
CarcinomahepatocellularNeovascularizationpathologicTomographyX-ray computedMagnetic resonance imagingRadionuclide imaging
DOI:
10.3760/cma.j.issn.1673-4114.2013.01.015
摘要:
肝细胞癌(HCC)肿瘤新生血管的生成在肿瘤的发生、进展及转移中起着重要的作用,肿瘤新生血管的结构与正常血管具有明显差异。免疫组化法测定微血管密度虽为评价肿瘤新生血管的"金标准",但该方法是一项有创性的检查,其临床应用受到限制。多排螺旋CT、MRI、超声及核医学显像检查等无创的影像学检查方法以及数字减影血管造影等已广泛应用于临床上对HCC肿瘤新生血管的评价,可以为HCC的定性诊断提供依据。光学成像、同步辐射X射线成像等分子影像学方法也逐步应用于HCC肿瘤新生血管评价的动物实验研究中。
Abstract:
Tumor neoangiogenesis plays an important role in growth and metastasis of human hepatocellular carcinoma (HCC).Angiogenesis induced by tumor cells is different from the normal vessels.Microvessel density measured by immunohistochemistry is used as the gold standard for assessment of angiogenesis,but it is an invasive diagnostic method and its clinical application is restricted.Digital subtraction angiography and noninvasive imaging examinations such as multi-slice spiral CT,MRI,ultrasound,nuclear medicine diagnosis are widely used in clinic for assessment of angiogenesis induced by tumor cells,which can play an important role in clinical diagnosis of HCC and assessment of the treatment effect of inhibiting angiogenesis induced by tumor cells.Molecular images such as optical imaging and synchrotron radiation X-ray imaging are gradually used in the experimental study of assessment of angiogenesis induced by tumor cells.

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备注/Memo

备注/Memo:
收稿日期:2012-07-12。
通讯作者:石洪成,Email:shihongcheng@sina.com
更新日期/Last Update: 1900-01-01