[1]陈敏,魏玲格,刘晓梅.肿瘤血管生成的分子影像学研究进展[J].国际放射医学核医学杂志,2012,36(2):65-68.[doi:10.3760/cma.j.issn.1673-4114.2012.02.001]
　CHEN Min,WEI Ling-ge,LIU Xiao-mei.Advances of molecular imaging in tumor angiogenesis[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(2):65-68.[doi:10.3760/cma.j.issn.1673-4114.2012.02.001]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
36
期数:
2012年第2期
页码:
65-68
栏目:
实验核医学
出版日期:
2012-03-25

文章信息/Info

Title:
Advances of molecular imaging in tumor angiogenesis
作者:
陈敏;  魏玲格;  刘晓梅
河北医科大学第三医院核医学科, 石家庄 050051
Author(s):
CHEN Min;  WEI Ling-ge;  LIU Xiao-mei
Department of Nuclear Medicine, the Third Affiliated Hospital of Hebei Medical University, Shijiazhuang 050051, China
关键词:
肿瘤; 新生血管化; 病理性; 分子探针技术; 成像技术
Keywords:
Neoplasms; Neovascularization;  pathologic; Molecular probe techniques; Imaging techniques
DOI:
10.3760/cma.j.issn.1673-4114.2012.02.001
摘要:
肿瘤血管生成与肿瘤的生长、恶变、转移以及患者的预后有着密切的关系,因此,肿瘤的抗血管生成治疗引起了人们的极大兴趣.分子影像学应用高亲和力的分子探针与靶分子特异性结合的原理,可在活体细胞和分子水平上特征性地显示及测量生物机体的生化过程.近年来,分子影像学技术在肿瘤血管生成的可视化及定量研究中取得了一定的进展,有望成为肿瘤早期诊断与靶向治疗评价的重要手段.该文综述了肿瘤血管生成的分子影像学技术的最新进展。
Abstract:
Tumor angiogenesis has a close relationship with tumor growth,progression,metastasis and the prognosis of tumor patients.Therefore,tumor anti-angiogenic treatment arouses great public interest.Molecular imaging can characteristically display and measure the biochemical process of organisms at cellular and molecular level in vivo,which is based on the specific binding of molecular probe with high affinity and target molecules.In recent years,molecular imaging has a certain progress on visual and quantitative research of tumor angiogenesis and it is expected to become an important technique in the efficacy evaluation and prognostic assessment.This article summarizes the new advances of molecular imaging technology in tumor angiogenesis.

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备注/Memo

备注/Memo:
收稿日期:2012-01-10。
通讯作者:刘晓梅,Email:ky121@l63.com
更新日期/Last Update: 1900-01-01