[1]季泽强,缪蔚冰.99Tcm-DTPA肾动态显像与血清胱抑素C测定法在肾小球功能评价中的对比研究[J].国际放射医学核医学杂志,2010,34(6):357-359.[doi:10.3760/cma.j.issn.1673-4114,2010.06.010]
　JI Ze-qiang,MIAO Wei-bing.Comparative study between 99Tcm-MDP renal dynamic imaging and measurement of serum cystatin C in evaluation of glomerular function[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):357-359.[doi:10.3760/cma.j.issn.1673-4114,2010.06.010]
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99Tcm-DTPA肾动态显像与血清胱抑素C测定法在肾小球功能评价中的对比研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第6期
页码:
357-359
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Comparative study between 99Tcm-MDP renal dynamic imaging and measurement of serum cystatin C in evaluation of glomerular function
作者:
季泽强;  缪蔚冰
福建医科大学附属第一医院核医学科, 福州 350005
Author(s):
JI Ze-qiang;  MIAO Wei-bing
Department of Nuclear Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China
关键词:
肾小球滤过率; 99m锝五乙酸盐; 胱抑素C
Keywords:
Glomerular filtration rate; Technetium Tc 99m pentetate; Cystatin C
DOI:
10.3760/cma.j.issn.1673-4114,2010.06.010
摘要:
目的 比较99Tcm-二亚乙基三胺五乙酸(99Tcm-DTPA)肾动态显像和血清胱抑素C测定两种方法在评价肾小球滤过功能中的差别。方法 随机抽取100例患者,其中高血压病患者38例、肾脏病患者35例、动脉硬化性闭塞症患者10例、糖尿病患者9例、其他疾病患者8例。分别通过99Tcm-DTPA肾动态显像法和血清胱抑素C测定法评估肾小球滤过功能。结果 两种方法所测得的肾小球滤过率(GFR)差异无统计学意义(t=1.591,P>0.05),且呈线性相关(r=0.809,P<0.01);放射性核素肾动态显像法在测定GFR的同时,还可以获得分肾功能,观察双肾血流灌注和排泄状况。结论 用99Tcm-DTPA肾动态显像与血清胱抑素C测定两种方法评估GFR,结果无显著差异,且相关性很好。前者可以获得分肾功能,对肾功能状态的评估更为全面;而后者测定方法简便、省时,且价廉,更适合于对临床患者肾功能的筛查。
Abstract:
Objective To compare the difference between 99Tcm-diethylenetriaminepentaacetic acid (99Tcm-DTPA) renal dynamic imaging and measurement of serum cystatin C in evaluation of glomerular filtration rate (GFR).Methods One hundred patients were selected at random, 38 cases with hy-pertension, 35with nephrosis, 10 with arteriosclerosis obliterans, 9 with diabetes and 8 with other diseases. Evaluation of patients’GFR was made separately by 99Tcm-DTPA renal dynamic imaging and measurement of serum cystatin C.Results No significant difference of GFR was found between the two methods (t=1.591, P>0.05),and linear correlation was showed as well (r=0.809, P<0.01). The imaging also revealed the function of individaul kidney, renal blood perfusion and excretory function besides GFR.Conclusion s Results of GFR from the two methods revealed no significant difference and they were highly correlated. 99Tcm-DTPA renal dynamic imaging could reveal the individual renal function and provide a more comprehensive evaluation of renal function while the measurement of serum cystatin C was simple and convenient, timesaving, economic, and more suit-able for screening patients’renal function clinically.

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备注/Memo

备注/Memo:
收稿日期:2010-07-22。
通讯作者:缪蔚冰(E-mail:miaoweibing@126.com)
更新日期/Last Update: 1900-01-01