[1]邓艳,张伟.125I-碘酞酸盐临床应用进展[J].国际放射医学核医学杂志,2016,40(3):225-229.[doi:10.3760/cma.j.issn.1673-4114.2016.03.012]
 Deng Yan,Zhang Wei.125I-iothalamate clinical applications[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):225-229.[doi:10.3760/cma.j.issn.1673-4114.2016.03.012]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
40
期数:
2016年第3期
页码:
225-229
栏目:
出版日期:
2016-05-25

文章信息/Info

Title:
125I-iothalamate clinical applications
作者:
邓艳1 张伟2
1. 646000, 泸州, 西南医科大学附属医院急诊科;
2. 610072, 成都, 四川省医学科学院, 四川省人民医院核医学科
Author(s):
Deng Yan1 Zhang Wei2
1. Department of Emergency, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China;
2. Department of Nuclear Medicine, Sichuan Provincial Academy of Medical Science, Sichuan Province People’s Hospital, Chengdu 610072, China
关键词:
碘放射性同位素肾小球滤过率肝移植肾移植碘酞酸盐
Keywords:
Iodine radioisotopesGlomerular filtration rateLiver transplantationKidney transplantationIothalamate
DOI:
10.3760/cma.j.issn.1673-4114.2016.03.012
摘要:
125I-碘酞酸盐在美国应用至今已超过半个多世纪。其主要应用于评价肾小球滤过率(GFR),特别是在肝肾移植患者中肾功能的评价上具有非常重要的作用,具有方法简单、准确的特点。目前国内大多采用内生肌酐清除率、99Tcm-DTPA肾动态显像或者99Tcm-DTPA双血浆法来测定GFR。但这些方法评估GFR的价值有限。笔者将系统阐述125I-碘酞酸盐的原理、方法、临床应用、辐射安全等,以期为国内临床应用奠定基础。
Abstract:
125I-iothalamate or Glofil-125 has been widely applicated in the US more than half a century. It mainly applies to the evaluation of glomerular filtration rate(GFR), particularly a very important role in liver and kidney transplant patients on monitoring of renal function. This is a simple, accurate method. However, most of the current domestic use of endogenous creatinine clearance rate, 99Tcm-DTPA renal dynamic imaging or 99Tcm-DTPA double plasma method to determine the GFR. However, these methods had a limited value to assessment GFR. This article describes the system 125I-iothalamate principles, methods, clinical applications, radiation safety, etc., in order to lay the foundation for domestic clinical application.

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备注/Memo

备注/Memo:
收稿日期:2016-03-10
基金项目:泸州市科技局青年基金(2014-S-45);西南医科大学青年基金(2014QN-019)
通讯作者:张伟,Email:zhangwscd@163.com
更新日期/Last Update: 1900-01-01