[1]周翔,尹红燕,张一帆.报告基因显像监测干细胞治疗的研究进展[J].国际放射医学核医学杂志,2010,34(5):262-265.[doi:10.3760/cma.j.issn.1673-4114.2010.05.002]
 ZHOU Xiang,YIN Hong-yan,ZHA NG Yi-fan.Advances of reporter gene monitoring stem cell therapy[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(5):262-265.[doi:10.3760/cma.j.issn.1673-4114.2010.05.002]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第5期
页码:
262-265
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Advances of reporter gene monitoring stem cell therapy
作者:
周翔 尹红燕 张一帆
200025, 上海交通大学医学院附属瑞金医院核医学科
Author(s):
ZHOU Xiang YIN Hong-yan ZHA NG Yi-fan
Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai 200025, China
关键词:
基因报告干细胞放射性核素显像分子影像技术
Keywords:
GenereporterStem cellsRadionuclide imagingMolecular imaging technology
DOI:
10.3760/cma.j.issn.1673-4114.2010.05.002
摘要:
干细胞治疗的研究展示了广阔的应用前景,但干细胞治疗作为一种新的疾病治疗手段,仍存在着很多亟待解决的问题。报告基因显像是近年来发展迅速的一种无创、灵敏的监测干细胞的方法,特别是放射性核素报告基因显像具有灵敏度高和特异性强的优点,并可进行深部组织显像和重复显像,是在活体条件下示踪干细胞最具潜力的技术,展示了良好的应用前景。
Abstract:
Stem cell therapy research has made great progress, demonstrating a broad application prospects. However, stem cell therapy as a new disease treatment, there are still many problems to be solved.Reporter gene imaging is a rapid development in recent years, a non-invasive, sensitive method of monitoring of stem cells, in particular radionuclide reporter gene imaging has high sensitivity and specificity of the advantages of strong and can carry out imaging of deep tissue and repeat imaging, is a tracer in vivo conditions, the most promising stem cell transplantation technique, showing good prospects for development.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2010-04-23。
基金项目:国家自然科学基金(30570525),上海市重点学科建设项目(S30203)
通讯作者:张一帆,E-mail:zhangyifanl992@yahoo.com.cn
更新日期/Last Update: 1900-01-01