[1]李继涛,何明远,袁德晓,等.p53调控的能量代谢对辐射效应的影响[J].国际放射医学核医学杂志,2012,36(6):380-384.[doi:10.3760/cma.j.issn.1673-4114.2012.06.014]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
36
期数:
2012年第6期
页码:
380-384
栏目:
放射生物学
出版日期:
1900-01-01

文章信息/Info

Title:
Influence of p53-regulated energy metabolism in radiation effects
作者:
李继涛 何明远 袁德晓 沈波 邵春林
上海复旦大学放射医学研究所放射生物部, 上海 200032
Author(s):
LI Ji-tao HE Ming-yuan YUAN De-xiao SHEN Bo SHAO Chun-lin
Department of Radiation Biology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, China
关键词:
基因p53能量代谢辐射效应肿瘤放射疗法
Keywords:
Genes p53Energy metabolismRadiation effectsNeoplasmsRadiotherapy
DOI:
10.3760/cma.j.issn.1673-4114.2012.06.014
摘要:
p53基因一直是肿瘤病因学、放射生物学的研究热点,但受其调控的能量代谢在辐射生物效应中的作用还存在许多未知因素。了解p53基因调控的能量代谢对探讨肿瘤放射治疗疗效、辐射损伤、辐射致癌的早期筛选生物指标和分子流行病学调查均有着极其重要的意义。该文概述了此方面的研究进展。
Abstract:
p53 is a hot spot in the studies of tumor etiology and radiobiology, but the function of p53-reguated energy metabolism in radiation biological effects still remains many uncertainties. The in-depth study of p53-regulated energy metabolism is of great significance to investigate the tumor radiotherapy efficacy, radiation damage, carcinogenesis and even molecular epidemiology. The current research progress at this point was stated in this article.

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备注/Memo

备注/Memo:
收稿日期:2012-06-21。
基金项目:国家自然科学基金(11179002,81273001)
通讯作者:邵春林(Email:clshao@shmu.edu.cn)
更新日期/Last Update: 1900-01-01