[1]张怡,袁卫红.硒与自身免疫性甲状腺疾病[J].国际放射医学核医学杂志,2012,36(6):376-379.[doi:10.3760/cma.j.issn.1673-4114.2012.06.013]
　ZHANG Yi,YUAN Wei-hong.Selenium and autoimmune thyroid disease[J].International Journal of Radiation Medicine and Nuclear Medicine,2012,36(6):376-379.[doi:10.3760/cma.j.issn.1673-4114.2012.06.013]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
36
期数:
2012年第6期
页码:
376-379
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Selenium and autoimmune thyroid disease
作者:
张怡;  袁卫红
昆明医科大学第二附属医院核医学科, 昆明 650101
Author(s):
ZHANG Yi;  YUAN Wei-hong
Department of Nuclear Medicine, the Secord Affiliated Hospital of Kunming University, Kunming 650101, China
关键词:
硒; 自身免疫; 甲状腺疾病
Keywords:
Selenium; Autoimmune; Thyroid disease
DOI:
10.3760/cma.j.issn.1673-4114.2012.06.013
摘要:
硒作为人体必需的一种微量元素,在机体中参与甲状腺激素的合成、活化及代谢,从而影响甲状腺功能。在自身免疫性甲状腺疾病(AITD)中,硒的水平低于正常值。低硒可能通过影响甲状腺的滤泡上皮细胞内多种含硒蛋白酶和(或)影响机体的免疫功能而导致AITD的发生与发展。给AITD患者补硒,为该病的治疗和预后开辟了一条新路。
Abstract:
As one of the essential trace elements, selenium takes part in the synthesis, activation and metabolism of thyroid hormones so as influencing thyroid function. In autoimmune thyroid disease, the level of selenium is lower than normal. The low serum selenium level may have impact on the multiple selenoproteinase on the surface of follicular epithelial cell or on the immune system of the body resulting in the occurrence and progression of thyroid disease. Selenium supplementation should be one of the potential and new measures for the prevention and therapy of autoimmune thyroid disease.

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相似文献/References:

[1]胡小春,蒋宁一,李敬彦,等.硒对经131I治疗Graves病患者血清甲状腺过氧化物酶抗体水平的影响[J].国际放射医学核医学杂志,2015,39(2):140.[doi:10.3760/cma.j.issn.1673-4114.2015.02.008]
　Hu Xiaochun,Jiang Ningyi,Li Jingyan,et al.Effect of additional selenium on the levels of serum thyroid peroxidase antibody in patients with Graves disease treated with 131I[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(6):140.[doi:10.3760/cma.j.issn.1673-4114.2015.02.008]

备注/Memo

备注/Memo:
收稿日期:2012-07-24。
通讯作者:袁卫红(Email:yuantianhe@163.com)
更新日期/Last Update: 1900-01-01