[1]陈贵兵,蒋宁一,刘生,等.腺苷试验与运动试验201Tl心肌灌注显像对冠心病诊断价值的比较[J].国际放射医学核医学杂志,2007,31(2):80-82.
　CHEN Gui-bin,JIANG Ning-yi,LIU Sheng,et al.Comparison of adenosine stress and exercise stress 201Tl myocardial perfusion imaging for diagnosis of coronary heart disease[J].International Journal of Radiation Medicine and Nuclear Medicine,2007,31(2):80-82.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
31
期数:
2007年第2期
页码:
80-82
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Comparison of adenosine stress and exercise stress 201Tl myocardial perfusion imaging for diagnosis of coronary heart disease
作者:
陈贵兵1;  蒋宁一2;  刘生2;  卢献平2;  梁九根2;  张弘2;  吴华1
1. 361003 厦门, 福建医科大学附属厦门第一医院核医学科;
2. 510120 广州, 中山大学附属第二医院核医学科
Author(s):
CHEN Gui-bin1;  JIANG Ning-yi2;  LIU Sheng2;  LU Xian-ping2;  LIANG Jiu-gen2;  ZHANG Hong2;  WU Hua1
1. Department of Nuclear Medicine, the First Hospital, Fujian Medical University, Xiamen 361003, China;
2. Department of Nuclear Medicine, the Secondary Affiliated Hospital, Zhongshan University, Guangzhou 510120, China
关键词:
冠状动脉疾病; 心肌灌注显像; 运动试验; 腺苷; 铊放射性同位素; 对比研究
Keywords:
Coronary disease; Myocardial perfusion imaging; Exercise test; Adenosine; Thallium radioisotopes; Comparison study
分类号:
R817.4
摘要:
目的 比较腺苷试验与运动试验201Tl心肌灌注显像对冠心病的诊断价值。方法 将41例临床疑诊冠心病患者随机分为两组,一组进行腺苷试验201Tl心肌灌注显像,一组进行运动试验201Tl心肌灌注显像。两组试验对象均同期(2周内)行冠状动脉造影术。以冠状动脉狭窄≥50%作为冠心病诊断的"金标准",比较两种负荷方法对冠心病的诊断价值。结果 腺苷试验201Tl心肌灌注显像对冠心病诊断的灵敏度、特异度、阳性预测率、阴性预测率、准确率分别为92.86%、57.14%、81.25%、80.0%、80.95%,运动试验201Tl心肌灌注显像分别为100%、60.0%、71.43%、100%、80.0%,两种负荷方法对病变冠状动脉的检出率分别为66.67%和72.22%。结论 两种负荷方法诊断冠心病的总体效能无显著差异。
Abstract:
Objective The aim of this study was to compare the diagnostic values of adenosine and exercise stress 201Tl myocardial perfusion imaging for detecting coronary heart disease (CHD). Methods 41 patients with suspected CHD were randomly divided into two groups. In one group adenosine stress was submitted, the exercise stress myocardial SPECT was performed in another. Coronary angiography (CAG) was performed in each patient within 2 weeks before or after SPECT. The result of CAG was taken as "gold standard" of CHD. They compared the diagnostic value of two methods. Results In adenosine group, the sensitivity, specificity, positive predictive value, negative predictive value, accuracy are 92.86%, 57.14%, 81.25%, 80.00%, 80.95% respectively. In exercise stress group, are 100%, 60.0%, 71.43%, 100%, 80.00% respectively. Detection rates of coronary artery lesions were 66.67% and 72.22% in two groups respectively. Conclusion Adenosine stress testing and exercise stress testing 201Tl myocardial perfusion imaging may provide similar value for detection of CHD.

参考文献/References:

1 田月琴,王金城,何作祥,等.腺苷负荷试验心肌灌注显像诊断冠心病的临床价值.中华心血管病杂志,2005,33(1):58-61.
2 陈贵兵,蒋宁一,刘生,等.腺苷试验201Tl心肌灌注显像不良反应及对冠心病诊断价值的初步临床研究.中国临床医学影像杂志,2006,17(7):372-375.
3 Nishimura S, Nishimura T, Yamazaki J, et al. Comparison of myocardial perfusion imaging by thallium-201 single-photon emission computed tomography with SUNY4001(adenosine) and exercise-crossover clinical trail at multi-center. Kaku Igaku, 2004,41(2):143-154.
4 Cuocolo A, Nicolai E, Soricelli A, et al. Technetium 99m-labeled tetrofsmin yocardial tomography in patients with coronary artery disease:comparison between adenosine and dynamic exercise stress testing. J Nucl Cardiol, 1996, 3(3):194-203.
5 Levine MG, Ahlberg AW, Mann A, et al. Comparison of exercise,dipyridamole, adenosine, and dobutamine stress with the use of Tc-99m tetrofosmin tomographic imaging. J Nucl Cardiol, 1999, 6(4):389-396.

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备注/Memo

备注/Memo:
收稿日期:2006-08-22。
通讯作者:蒋宁一(E-mail:ningyij@163.net)
更新日期/Last Update: 1900-01-01