[1]金星,唐明灯,林端瑜,等.核素骨显像在71例骨外恶性淋巴瘤的临床应用[J].国际放射医学核医学杂志,2006,30(4):229-231.
　JIN Xing,TANG Ming-deng,LIN Duan-yu,et al.The clinical application of nuclide bone imaging in malignant lymphomas[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(4):229-231.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第4期
页码:
229-231
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The clinical application of nuclide bone imaging in malignant lymphomas
作者:
金星;  唐明灯;  林端瑜;  倪雷春
350014 福州, 福建省肿瘤医院核医学科
Author(s):
JIN Xing;  TANG Ming-deng;  LIN Duan-yu;  NI Lei-chun
Department of Nuclear Medicine, Fujian Tumor Hospital, Fuzhou 350014, China
关键词:
淋巴瘤; 骨骼; 99m锝美罗酸盐
Keywords:
Lymphoma; Skeleton; Technetium 99m medronate
分类号:
R817.4
摘要:
目的 探讨核素骨显像在恶性淋巴瘤骨浸润中的临床应用价值。方法 收集经病理证实的71例恶性淋巴瘤骨显像患者病例,其中霍奇金淋巴瘤(HL)8例,非霍奇金淋巴瘤(NHL)63例。经静脉注射99mTc-亚甲基二瞵酸盐(99mTc-MDP)555-925MBq后2.5-6h行全身骨显像检查。结果 骨浸润病变者31例,其中8例HL中骨浸润3例,63例NHL中骨浸润28例。总病灶数103个,除2个骨放射性缺损外,101个浓聚灶分别为:脊柱35个(34.65%)、四肢骨及关节30个(29.70%)、肋骨14个(13.86%)、骨盆13个(12.87%)、颅骨5个(4.95%)及胸骨4个(3.96%)。结论 核素骨显像在恶性淋巴瘤骨浸润的临床分期、治疗监测和预后转归等方面具有较高的临床价值。
Abstract:
Objective To evaluate the clinical application value of nuclide bone imaging in malignant lymphoma. Methods 71 cases of patients were diagnosed by pathology as malignant lymphoma, among whom there were 8 cases of Hodgkin disease(HL) and 63 cases of non-Hodgkin disease (NHL). The examinations were performed from 2.5 to 6 hours later after the intravenous injection of 99mTc-MDP (555-925MBq). Results 31 cases were bone-infiltrating lesions, including 3 cases of HL and 28 cases of NHL The total number of the focus was 103, except 2 cases of bone lack, including 35 foci in vertebral column (34.65%), 30 foci in limb and joint (29.70%), 14 foci in rib (13.86%), 13 foci in elvis (12.9%), 5 foci in skull (4.95%) and 4 foci in sternum (3.96%). Conclusion The nuclide bone imaging has a high value in the clinical stage, therapeutic observation and prognosis of bone-infiltrating malignant lymphoma.

参考文献/References:

1 Orzel JA,Sawaf NW,Richardson ML Lymphoma of skeleton:Scintigraphic evaluation.Am J Roentgenol,1988,150(5):1095-1099.
2 李伟,屈婉莹,王玉华,等.骨显像在骨外恶性淋巴瘤的应用.中国临床医学影像杂志,2003,14(2):133-134.
3 王辉,田伟家、陈钰,等.Ga-67和Tc-99m-VDP显像在淋巴瘤骨转移的临床研究.中国临床医学影像杂志,2000,11(增刊):62-64.
4 Even-Sapir E.Imaging of malignant bone involvement by morphologic,scintigraphic,and hybrid modalities.J Nucl Med,2005,46(8):1356-1367.
5 陈喜林,张伟京.18F-DG PET显像技术在恶性淋巴瘤中的临床应用价值.白血病·淋巴瘤,2004,13(1):46-47.

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备注/Memo

备注/Memo:
收稿日期:2006-02-22。
通讯作者:金星,E-mail:jinxing7766@163.com
更新日期/Last Update: 1900-01-01