参考文献/References:
1 盛树力.老年性痴呆:从分子生物学到临床诊治.北京:科学技术出版社,1998.61-73.
2 Jarrett JT,Berger EP,Lansbury PT Jr,et al.The carboxy terminus of the β-amyloid protein is critical for the seeding of amyloid formation:implications for the pathogenesis of Alzheimer’s disease.Biochemistry,1993,32(18):4693-4697.
3 Wisiniewski TM,Wadghiri YZ.Detection of Alzheimer’s amyloid by magnetic resonance imaging.Proceedings of the Society for Neuroscience,31st Annual Meeting,2001.
4 Friedland RP,Kalaria R,Berridge M,et al.Neuroimaging of vessel amyloid in Alzheimer’s disease.Ann NY Acad Sci,1997,826:242-247.
5 Zhuang ZP,Kung MP,Hou C,et al.Radioiodinated styrylbenzenes and thio flavins as probes for amyloid aggregates.J Med Chem,2001,44(12):1905-1914.
6 Mathis CA,Holt DP.In vivo evalution and imaging of a lipohilic derivative of Congo red for amyloid assessment.J Nucl Med,2001,42:252.
7 Klunk WE,Bacskai BJ,Mathis CA,et al.Imaging amyloid-beta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04,a systemically administered Congo red derivative.J Neuropathol Exp Neurol,2002,61(9):797-805.
8 Klunk WE,Wang Y,Huang GF,et al.Uncharged thioflavin-t derivatives bind to amyloid-beta protein with high affinity and readily enter the brain.Life Sci,2001,69(13):1471-1484.
9 Kung MP,Hou C,Zhuang ZP,et al.IMPY:an improved thioflavin-T derivative for in vivo labeling of β-amyloid plaques.Brain Res.2002,956(2):202-210.
10 Zhuang ZP,Kung MP,Wilson A,et al.Structure-activity relationship of imidazo[1,2-a] pyridines as ligands for detecting β-amyloid plaques in the brain.J Med Chem,2003,46(2):237-243.
11 Agdeppa ED,Kepe V,Liu J,et al.Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethyl-idene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer’sdisease.J Neurosci,2001,21(24):RC189.
12 Agdeppa ED,Kepe V,Liu J,et al.2-Dialky lamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs):novel diagnostic and therapeutic tools in Alzheimer’s disease.Mol Imaging Biol,2003,5(6):404-417.
13 Shoghi-Jadid K,Small GW,Agdeppa ED,et al.Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease.Am J Geriatr Psychiatry,2002,10(1):24-35.
14 Jagust W.The proteomics of positron emission tomography.Ann Neurol,2004,55(3):303-305.
15 Klunk WE,Engler H,Nordberg A,et al.Imaging brain amyloid in Alzheimer’s disease with pittsburgh compound-B.Ann Neurol,2004,55(3):306-319.
16 Schmitt FA,Davis DG,Wekstein DR,et al."Preclinical" AD revisited: neuropathology of cognitively normal older adults.Neurology,2000,55(3):370-376.
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