[1]余丰文,冯彦林,贺小红,等.PET-CT与钼靶X线、B超定性诊断乳腺癌的临床对比研究[J].国际放射医学核医学杂志,2006,30(3):148-151.
　YU Feng-wen,FENG Yan-lin,HE Xiao-hong,et al.Evaluation of PET-CT versus mammography and ultrasonography in detecting breast neoplasms[J].International Journal of Radiation Medicine and Nuclear Medicine,2006,30(3):148-151.
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PET-CT与钼靶X线、B超定性诊断乳腺癌的临床对比研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
30
期数:
2006年第3期
页码:
148-151
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Evaluation of PET-CT versus mammography and ultrasonography in detecting breast neoplasms
作者:
余丰文;  冯彦林;  贺小红;  刘德军;  温广华;  袁建伟
528000 佛山, 广东省佛山市第一人民医院核医学科
Author(s):
YU Feng-wen;  FENG Yan-lin;  HE Xiao-hong;  LIU De-jun;  WEN Guang-hua;  YUAN Jian-wei
Department of Nuclear Medicine, the First people’s Hosptial of Foshan, Foshan 528000, China
关键词:
乳腺肿瘤; 体层摄影术; 发射型计算机; B超; 放射摄影术; 对比研究
Keywords:
Mammary neoplasms; Tomography; emission-computed; Ultrasonography; Radiography; Comparative study
分类号:
R445;R817.4
摘要:
目的 探讨18F-氟代脱氧葡萄糖(18F-FDG)PET-CT诊断乳腺癌的临床应用价值。方法 60例临床怀疑乳腺癌的患者分别行B超、钼靶X线乳腺摄影和PET-CT检查。结合术后病理,比较PET-CT、B超、钼靶X线乳腺摄影诊断乳腺癌的结果。结果 手术病理证实乳腺癌48例,良性病变12例。PET-CT目测法诊断乳腺癌的灵敏度、特异度、准确率及阳性预测值分别为93.8%、83.3%、91.7%及95.7%,钼靶X线法分别为81.3%、83.3%、81.7%及95.1%,B超法分别为85.4%、83.3%、85.0%及95.3%。三种方法对乳腺癌的诊断效能无显著差异性(χ2=3.40,P>0.5)。结论 18F-FDGPET-CT诊断乳腺癌具有很好的临床应用价值,并能对乳腺癌的分期提供更多的信息。
Abstract:
Objective To evaluate the clinical value of 18F-fluorodeoxyglucose(18F-FDG) PET-CT imaging in detecting breast cancer.Methods 60 patients with suspicious masses underwent 18F-FDG PET-CT imaging, mammography and ultrasonography respectively. The results of the histopathology after surgery were used as diagnostic golden standard. The uptaking of 18F-FDG in the breast masses was analyzed using semiquantitative and qualitative methods. The findings of PET-CT,mammography and ultrasonography in detecting breast cancer were compared.Results 48 malignant and 12 benign breast lesions of the 60 patients were proven histologically after surgery. The sensitivity, specificity, accuracy and positive predictive value obtained by PET-CT were 93.8%,83.3%,91.7% and 95.7%, respectively, and which were 81.3%,83.3%,81.7%,95.1% and 85.4%,83.3%,85.0%,95.3% with mammography and ultrasonographic. In the diagnostic ability among the three methods there was no significant difference showed(χ2=3.40,P>0.5).Conclusions PET-CT has higher degree of sensitivity, specificily and higher positive predictive value in breast cancer diagnosis and staging comparing to the mammography and ultrasonographic.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2006-03-17。
通讯作者:冯彦林(E-mail:fylin@syyy.com)
更新日期/Last Update: 1900-01-01