[1]张占春.电离辐射损伤与DNA修复基因[J].国际放射医学核医学杂志,2004,28(1):26-29.
 ZHANG Zhan-chun.Damage of ionizing radiation and DNA repair gene[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(1):26-29.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
28
期数:
2004年第1期
页码:
26-29
栏目:
放射医学
出版日期:
1900-01-01

文章信息/Info

Title:
Damage of ionizing radiation and DNA repair gene
作者:
张占春
315040 宁波,宁波市医疗中心李惠利医院肿瘤放疗科
Author(s):
ZHANG Zhan-chun
Radiotherapy Department of Ningbo Medical Center, Lihuili Hospital, Ningbo 315040, China
关键词:
辐射损伤DNA修复基因突变细胞株
Keywords:
radiation damageDNA repair generadiation-sensitive
分类号:
Q345+.7
摘要:
DNA辐射损伤直接影响复制、转录和蛋白质合成,进而影响细胞遗传、发育、生长和代谢等生命活动。DNA损伤还是突变的重要原因,而严重的突变可造成细胞癌变,导致肿瘤的发生。然而,生物体内存在着DNA损伤修复系统,其中DNA修复基因起着重要的作用。
Abstract:
DNA damage after exposure to ionizing radiation has a direct effect on DNA replication, transcription and protein synthesis.Further, heredity, development and metabolism of the cells can be affected.DNA damage was an importance factor for mutation of cells, furthermore, carcinogen can be caused by severe mutation.However, there is a DNA repair system in the organism, and especially DNA repair gene plays an important role for DNA damage.This review will briefly present DNA re-pair gene and its function.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2003-11-27。
基金项目:国家自然科学基金资助项目(39770238)
更新日期/Last Update: 1900-01-01