[1]张春丽,王荣福.肿瘤受体显像[J].国际放射医学核医学杂志,2000,24(3):124-127,141.
 ZHANG Chun-li,WANG Rong-fu.Tumor receptor imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(3):124-127,141.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第3期
页码:
124-127,141
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Tumor receptor imaging
作者:
张春丽 王荣福
100034 北京, 北京大学第一医院核医学科
Author(s):
ZHANG Chun-li WANG Rong-fu
Deptartment of Nuclear Medicine, The First Hospital of Beijing University, Beijing 100034, China
关键词:
肿瘤受体显像放射性核素标记
Keywords:
tumorreceptor imagingradiolabeling
分类号:
R817. 4
摘要:
肿瘤受体显像研究包括放射性标记配体的制备、配体与受体的体外分析及体内受体显像,肿瘤受体配体可用18F、123I(或131I)、111In与99Tcm标记,通过放射性受体结合分析、放射性自显影与受体特性分析,对其体外性能进行研究。神经多肽受体显像、类固醇受体显像与σ受体显像等已应用于多种肿瘤的诊断、分期、治疗方案选择与预后评价,其中神经多肽受体显像得到了较广泛的研究与应用。
Abstract:
Investigations on tumor receptor imaging include the preparation of radioligands, in vitro assays and in vivo receptor imaging. Ligands for tumor receptor imaging has been labeled by 18F、123I(or 131I)、111In or 99Tcm. In vitro assays can be performed by radioligand binding, autoradiography and receptor identification. Tumor receptor imaging such as neuropeptide receptor imaging, steroid receptor imaging and sigma receptor imaging has been used for diagnosis, staging, therapy strategy and prognosis of a wide range of tumors, of which the most widely studied was neuropeptide receptor imaging.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:1999-11-30。
作者简介:张春丽(1961-),女,河北沧州盐山人,北京大学第一医院核医学科副研究员,硕士,主要研究放射性药物、放射免疫显像;王荣福(1955-)男,福建南平浦城人,北京大学第一医院核医学科副教授,博士,主要研究神经受体显像、正电子显像。
更新日期/Last Update: 1900-01-01