[1]张晖,段清,卓娜,等.经直肠超声引导下“6+X”点法前列腺穿刺活检诊断前列腺癌的临床价值分析[J].国际放射医学核医学杂志,2015,39(4):308-310,335.[doi:10.3760/cma.j.issn.1673-4114.2015.04.008]
　Zhang Hui,Duan Qing,Zhuo Na,et al.Meta-analysis of the diagnostic value of transrectal ultrasound-guided “6+X” points biopsy in prostate cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(4):308-310,335.[doi:10.3760/cma.j.issn.1673-4114.2015.04.008]
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经直肠超声引导下“6+X”点法前列腺穿刺活检诊断前列腺癌的临床价值分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第4期
页码:
308-310,335
栏目:
出版日期:
2015-07-25

文章信息/Info

Title:
Meta-analysis of the diagnostic value of transrectal ultrasound-guided “6+X” points biopsy in prostate cancer
作者:
张晖;  段清;  卓娜;  田晶
天津医科大学第二医院超声科, 天津, 300211
Author(s):
Zhang Hui;  Duan Qing;  Zhuo Na;  Tian Jing
Department of Ultrasound, the Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China
关键词:
前列腺肿瘤; 活组织检查; 针吸; 超声检查; "6+X"点法; Meta分析
Keywords:
Prostatic neoplasms; Biopsy;  needle; Ultrasonography;  "6+X" biopsy; Meta-analysis
DOI:
10.3760/cma.j.issn.1673-4114.2015.04.008
摘要:
目的 探讨经直肠超声引导下前列腺穿刺活检诊断前列腺癌的临床价值。方法 检索PubMed、Embase、Cochrane Library、SCI、中国生物医学文献数据库、中国期刊全文数据库、中文科技期刊数据库、万方数据库等数据库,检索时间截至2015年1月。由3位研究者根据纳入与排除标准独立筛选文献、提取资料和评价质量,文献筛选严格按照纳入和排除标准,纳入研究的质量评估采用诊断性试验质量评价(QUADAS)评分量表,灵敏度合并、特异度合并、诊断比值比(DOR)及其95% CI、综合受试者工作特征(SROC)曲线下面积(AUC)和Q*指数均采用Meta-Disc 1.4软件进行统计学分析。结果 最终纳入5项基于中国人群的研究。荟萃结果显示:经直肠超声引导下前列腺穿刺活检诊断前列腺癌的灵敏度合并为0.84(95% CI为0.79~0.89),特异度合并为0.98(95% CI为0.94~0.99),DOR合并为170.95(95% CI为55.68~524.84),SROC AUC为0.9625,Q*指数为0.9082。结论 直肠超声引导下前列腺穿刺活检早期诊断前列腺癌具有很高的临床价值。
Abstract:
Objective To explore the diagnostic value of transrectal ultrasound-guided "6+X" points biopsy in prostate cancer.Methods All eligible databases were searched using the keywords,and the literature was evaluated by QUADAS.Statistical analysis was performed using Meta-Disc 1.4.Results Five studies satisfied the inclusion criteria.The transrectal ultrasound-guided "6+X" points biopsy in the diagnosis of prostate cancer exhibited the following characteristics:sensitivity,0.84(95% CI,0.79-0.89);specificity,0.98(95% CI,0.94-0.99);positive likelihood ratio,26.06(95% CI,2.87-236.68);negative likelihood ratio,0.21(95% CI,0.16-0.28);and diagnostic odds ratio,170.95(95% CI,55.68-524.84).The summary receiver operating characteristic curve indicated that the maximum joint sensitivity and specificity (Q*-value) were 0.9625,and the Q index value was 0.9082.Conclusion Transrectal ultrasonography combined with "6+X" method had high clinical value in the early diagnosis of prostate cancer.

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备注/Memo

备注/Memo:
收稿日期:2015-05-28。
基金项目:国家自然科学基金青年项目(项目编号:81202024)
通讯作者:田晶,Email:13821777622@163.com
更新日期/Last Update: 1900-01-01