[1]徐慧琴,薛杨央,赵学峰,等.18F-FDG PET-CT诊断前列腺癌复发与转移的价值[J].国际放射医学核医学杂志,2011,35(2):81-84.[doi:10.3760/cma.j.issn.1673-4114.2011.02.004]
　XU Hui-qin,XUE Yang-yang,ZHAO Xue-feng,et al.Value of 18F-FDG PET-CT in diagnoss of prostate cancer recurrence and metastasis[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(2):81-84.[doi:10.3760/cma.j.issn.1673-4114.2011.02.004]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第2期
页码:
81-84
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Value of 18F-FDG PET-CT in diagnoss of prostate cancer recurrence and metastasis
作者:
徐慧琴1;  薛杨央1;  赵学峰1;  梁朝朝2
1. 230022 合肥, 安徽医科大学第一附属医院核医学科;
2. 230022 合肥, 安徽医科大学第一附属医院泌尿外科
Author(s):
XU Hui-qin1;  XUE Yang-yang1;  ZHAO Xue-feng1;  LIANG Chao-zhao2
Department of Nuclear Medicine, The First Affiliated Hospital of A nhui Medical University, Hefei 230022, China
关键词:
前列腺肿瘤; 正电子发射断层显像术; 体层摄影术; X线计算机; 氟脱氧葡萄糖F18; 前列腺特异性抗原
Keywords:
Prostate neoplasms; Positron-emission tomography; Tomography; X-ray computed; Fluorodeoxyglucose Fl8; Prostate-specific antigen
DOI:
10.3760/cma.j.issn.1673-4114.2011.02.004
摘要:
目的 探讨18F-FDG PET-CT在前列腺癌复发、转移诊断中的价值。方法 回顾性分析23例前列腺癌治疗后随访期间临床怀疑复发、转移患者的18F-FDG显像资料,同期常规显像检查结果,病理及临床随访结果。结果 经病理及临床随访结果证实前列腺癌复发、转移者19例。PET-CT诊断为阳性者20例,其中1例盆腔脓肿、5例前列腺癌局部复发、8例盆腔淋巴结转移、1例全身多发淋巴结转移和5例骨转移;18F-FDG PET-CT诊断前列腺癌复发与转移的灵敏度为100%(19/19),特异度为75%(3/4),准确率为95%(22/23)。内分泌治疗后前列腺特异性抗原水平较稳定及逐渐升高者共12例,PET-CT均准确显示。与B超、CT、骨显像相比,PET-CT可发现更多的病灶。结论 18F-FDG PET-CT对前列腺癌复发、转移的诊断有重要价值。
Abstract:
Objective To investigate the value of 18F-FDG PET-CT on patients with suspected prostate cancer recurrence and metastasis. Methods Retrospective analysis 23 patients with prostate cancer who were suspected to have tumor recurrence and metastasis during follow-up, underwent 18F-FDG PET-CT examination. 18F-FDG PET-CT results were compared with those of conventional images, as referred to histopathology or clinical follow-up. Results In total, 19 patients with recurrence and metastasis were confumed by histopathology or clinical follow-up. Twenty patients were found to have positive lesion by 18F-FDG PET-CT, including the pelic abscess (1case), prostate cancer local recurrence (5cases), lymph node metastases(8cases), multiple systemic lymph node metastasis(lcase)and bone metastases(5cases). The sensitivity of 18F-FDG PET-CT was 100% (19/19) in diagnosis carcinoma recurrence and metastasis, and the specificity and accuracy were 75% (3/4) and 95%(22/23). The levels of prostate specific antigen in 12 patients gradually increased after endocrine theraphy, and PET-CT could dipit this accurately. Compared with conventional images such as B mode ultrasonic, CT, bone imaging, 18F-FDG PET-CT could find more focus. Conclusion 18F-FDG PET-CT imaging is valuable in diagnosing recurrent and metastatic prostate cancer.

参考文献/References:

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[4] Jorge RZ, Macarena R, Anibal RM, et al. Usefulness of PET scans in diagnosing recurrent prostate cancer. Prostate with PSA level < 5ng/ml. Actas Urol Esp, 2009, 33(8):844-852.
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备注/Memo

备注/Memo:
收稿日期:2011-02-03。
基金项目:安徽省科技计划项目(10021303025)
通讯作者:梁朝朝,Email:Liang-chaozhao@163.com
更新日期/Last Update: 1900-01-01