[1]张龙敏,刘爱连.前列腺癌MRI诊断技术研究进展[J].国际放射医学核医学杂志,2014,38(1):53-58.[doi:10.3760/cma.j.issn 1673-4114.2014.01.011]
 Zhang Longmin,Liu Ailian.Advances in MRI diagnosis of prostate cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(1):53-58.[doi:10.3760/cma.j.issn 1673-4114.2014.01.011]
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前列腺癌MRI诊断技术研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
38
期数:
2014年第1期
页码:
53-58
栏目:
出版日期:
2014-01-25

文章信息/Info

Title:
Advances in MRI diagnosis of prostate cancer
作者:
张龙敏 刘爱连
大连医科大学附属第一医院放射科, 115000
Author(s):
Zhang Longmin Liu Ailian
Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116000, China
关键词:
前列腺肿瘤磁共振成像功能显像
Keywords:
Prostatic neoplasmsMagnetic resonance imagingFunctional magnetic resonance imaging
DOI:
10.3760/cma.j.issn 1673-4114.2014.01.011
摘要:
前列腺癌是世界上第二常见的男性恶性肿瘤,我国前列腺癌的发病率亦呈逐年上升趋势。MRI有着良好的软组织分辨率及多方位成像优势,能较好地显示前列腺的解剖结构及相邻的组织结构,随着MRI技术的不断发展,其对前列腺癌的诊断发挥着越来越重要的作用。该文从前列腺癌MRI常规序列的影像表现着手,对各种功能MRI在前列腺癌的诊断和鉴别诊断中的应用进行了详细地论述,如MR灌注加权成像、MR波谱、MR扩散加权成像、MR扩散张量成像、体素内不相干运动扩散加权成像、MR磁敏感加权成像等,介绍了功能MRI相对于常规扫描的优势及其所能提供的更多的影像学资料,通过系列半定量和定量数据,能进一步提供前列腺癌的血流灌注、水分子扩散、微循环状态、物质代谢及生化成分变化等信息。
Abstract:
Prostate cancer is the second most common cancer in the world, and the incidence of prostate cancer in China shows an upward trend. MRI has high soft tissue resolution and muhi-dimensional imaging advantages, and it can better show the anatomy of the prostate and adjacent tissue structures. With the development of MR technique, it plays a more and more important role in prostate cancer diagnosis. This review starts from the imaging performance of routine MRI sequence of prostate cancer, and a variety of functional MRI applications in the diagnosis and differential diagnosis of prostate cancer are described in detail, such as MR perfusion-weighted imaging, MR spectroscopy, MR diffusion-weighted imaging, MR diffusion tensor imaging, intravoxel incoherent motion diffusion-weight- ed imaging, MR susceptibility-weighted imaging. Meanwhile this review introduces that functional MRI has more advantages and can provide more image information than routine MRI sequence. According to a series of semi-quantitative and quantitative data, functional MRI can further provide the blood per- fusion of prostate cancer, water molecule diffusion and microcirculation state, metabolism and bio- chemical composition change information.

参考文献/References:

[1] 徐海青,段俊,吴边.全身骨显像诊断前列腺癌骨转移与PSA水平及病理分级的相关性研究.国际放射医学核医学杂志,2011,35(1):34-37.
[2] Nix JW,Turkbey B,Hoang A,et al. Very distal apical prostate tumours:identification on multiparametric MRI at 3 Tesla[J].BJU Int,2012,110(11 Pt B):E694-E700.
[3] Tüirkbey B,Bernardo M,Merino MJ,et al. MRI of localized prostate cancer:coming of age in the PSA era[J].Diagn Interv Radiol,2012,18(1):34-45.
[4] Soylu FN,Eggener S,Oto A. Local staging of prostate cancer with MRI[J].Diagn Interv Radiol,2012,18(4):365-373.
[5] 高炜,袁武,韩悦,等.前列腺解剖带区的断层切片与MRI图像对照研究[J].中国临床解剖学杂志,2011,29(4):413-417.
[6] 钱均琪,张绍渤,黄受方.前列腺癌的病理学进展[J].中华病理学杂志,1996,25(4):253-256.
[7] Franiel T,Hamm B,Hricak H. Dynamic contrast-enhanced magnetic resonance imaging and pharmacokinetic models in prostate cancer[J].Eur Radiol,2011,21(3):616-626.
[8] 袁宪顺,修建军,宁国庆,等.表观扩散系数和MR动态增强对前列腺中央腺体疾病的价值[J].医学影像学杂志,2012,22(4):639-642,647.
[9] Chen YJ,Chu WC,Pu YS,et al. Washout gradient in dynamic contrast-enhanced MRI is associated with tumor aggressiveness of prostate cancer[J].J Magn Reson Imaging,2012,36(4):912-919.
[10] 朱海滨,江柳,杨学东,等.MR动态增强定量参数Ktrans值对前列腺外周带T2WI低信号病灶的鉴别诊断价值[J].实用放射学杂志,2012,28(12):1838-1841,1851.
[11] 朱海滨,刘婧,蔡文超,等.前列腺癌MRI动态增强定量参数Ktrans值与Gleason评分的相关性研究[J].中国医学影像学杂志,2012,20(7):481-484.
[12] 刘明,郭志.动态增强MRI在评价前列腺肿瘤微血管生成的临床应用[J].国际医学放射学杂志,2012,35(2):143-146.
[13] 李春媚,陈敏,李飒英,等.前列腺癌MR动态增强扫描定量分析及其应用[J].中华放射学杂志,2011,45(5):508-510.
[14] 李彦娴,袁曙光,赵新湘,等.常规MRI联合PWI对前列腺癌的诊断价值研究[J].现代泌尿生殖肿瘤杂志,2011,3(5):264-268.
[15] 袁宇啸,王滨,王锡臻,等.前列腺癌MRI灌注指标与ADC值的相关性研究[J].现代生物医学进展,2010,10(9):1692-1694.
[16] 赵新,白人驹,孙浩然,等.前列腺癌和良性前列腺增生磁共振灌注加权成像的应用价值[J].中华泌尿外科杂志,2009,30(3):207-209.
[17] 张海彬,胡道予,张娟.3.0T磁共振动脉自旋标记(ASL)技术诊断前列腺癌[J].放射学实践,2012,27(6):645-651.
[18] Kurhanewicz J,Vigneron DB,Hricak H,et al. Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high(0.24-0.70-cm3) spatial resolution[J].Radiology,1996,198(3):795-805.
[19] Scheidler J,Hricak H,Vigneron DB,et al. Prostate cancer:localization with three-dimensional proton MR spectroscopic imaging-clinicopathologic study[J].Radiology,1999,213(2):473-480.
[20] 王霄英,周良平,丁建平,等.MRS对中国人前列腺癌鉴别诊断标准的初步研究[J].中国医学影像技术,2004,20(8):1150-1153.
[21] Zakian KL,Sircar K,Hricak H,et al. Correlation of proton MR spectroscopic imaging with gleason score based on step-section pathologic analysis after radical prostatectomy[J].Radiology,2005,234(3):804-814.
[22] 程紫瑁,赵阳,白玫,等.MRS诊断前列腺癌准确率与病理切片Gleason评分的相关性研究[J].中国临床医学影像杂志,2012,23(12):860-863.
[23] 赵阳,徐勇,韩悦,等.MR波谱成像对前列腺癌分化程度预估价值的初步研究.中华放射学杂志,2011,45(10):951-954.
[24] 杨进军,贾文霄.MRS联合DWI对前列腺癌的诊断价值[J].中国肿瘤外科杂志,2011,3(5):285-289.
[25] 杨春,徐凯,郑骏年,等.Gd-DTPA对前列腺3T氢质子波谱影响的初步研究[J].中国医学计算机成像杂志,2011,17(4):332-334.
[26] 刘杰,张辉.GE3.0T扩散加权成像高b值在前列腺癌和非癌组织中的诊断价值[J].中国当代医药,2011,18(12):9-10.
[27] 何海青,樊树峰,陈邦文,等.MR扩散加权成像在前列腺病变中的诊断价值[J].医学影像学杂志,2009,19(2):187-191.
[28] Doo KW,Sung DJ,Park BJ,et al. Detectability of low and intermediate or high risk prostate cancer with combined T2-weighted and diffusion-weighted MRI[J].Eur Radiol,2012,22(8):1812-1819.
[29] 陈志强,郭雪梅,王霄英,等.前列腺癌扩散加权成像与Gleason评分的相关性研究[J].中国医学影像技术,2009,25(6):1066-1068.
[30] 吴建明,马周鹏,滕华英,等.不同b值下前列腺外周带癌灶ADC值的初步定量分析[J].医学影像学杂志,2011,21(6):890-893.
[31] 王微微,刘爱连.扩散张量成像在腹部的应用[J].国际医学放射学杂志,2011,34(3):257-260.
[32] 虞丹萍,王家平,袁曙光,等.DTI在正常前列腺的应用研究[J].临床放射学杂志,2012,31(2):232-235.
[33] 夏国金,龚洪翰,曾献军,等.MR扩散张量成像在前列腺癌诊断中的价值[J].中华放射学杂志,2012,46(6):526-528.
[34] 周洁,史长征,王永安,等.MRI弥散张量成像对前列腺疾病的诊断价值[J].暨南大学学报:自然科学与医学版,2011,32(2):233-237.
[35] Le Bihan D,Breton E,Lallemand D,et al. MR imaging of intravoxel incoherent motions:application to diffusion and perfusion in neurologic disorders[J].Radiology,1986,161(2):401-407.
[36] D?pfert J,Lemke A,Weidner A,et al. Investigation of prostate cancer using diffusion-weighted intravoxel incoherent motion imaging[J].Magn Reson Imaging,2011,29(8):1053-1058.
[37] 宋琼,马静,饶圣祥,等.MR全肝IVIM灌注分析对肝癌微循环功能状态的影像生物学标记物的评价研究[J].影像诊断与介入放射学,2013,22(3):181-184.
[38] Lemke A,Laun FB,Klauss M,et al. Differentiation of pancreas carcinoma from healthy pancreatic tissue using multiple b-values:comparison of apparent diffusion coefficient and intravoxel incoherent motion derived parameters[J].Invest Radiol,2009,44(12):769-775.
[39] Luciani A,Vignaud A,Cavet M,et al. Liver cirrhosis:intravoxel incoherent motion MR imaging-pilot study[J].Radiology,2008,249(3):891-899.
[40] Pang Y,Turkbey B,Bernardo M,et al. Intravoxel incoherent motion MR imaging for prostate cancer:an evaluation of perfusion fraction and diffusion coefficient derived from different b-value combinations[J].Magn Reson Med,2013,69(2):553-562.
[41] 王岳,蔡文超,叶锦棠,等.多b值DWI序列检测前列腺癌扩散和灌注信息的初步研究[J].实用放射学杂志,2012,28(12):1835-1837.
[42] 白岩,史大鹏,王梅云,等.磁敏感加权成像在鉴别诊断前列腺癌和良性前列腺增生中的价值[J].实用放射学杂志,2013,29(2):235-237.
[43] Song I,Kim CK,Park BK,et al. Assessment of response to radiotherapy for prostate cancer:value of diffusion-weighted MRI at 3T[J].A JR Am J Roentgenol,2010,194(6):W477-482.
[44] Kim CK,Park BK,Lee HM. Prediction of locally recurrent prostate cancer after radiation therapy:incremental value of 3T diffusion-weighted MRI[J].J Magn Reson Imaging,2009,29(2):391-397.
[45] Coakley FV,Teh HS,Qayyum A,et al. Endorectal MR imaging and MR spectroscopic imaging for locally recurrent prostate cancer after external beam radiation therapy:preliminary experience[J].Radiology,2004,233(2):441-448.
[46] 李鹏,陈志强.功能磁共振成像无创性评价前列腺癌治疗的研究进展[J].医学综述,2012,18(17):2857-2860.
[47] 蔡文超,李玮,李飞宇,等.前列腺癌内分泌治疗后体素内不均一运动扩散加权成像的初步研究[J].实用放射学杂志,2012,28(12):1823-1826.

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备注/Memo

备注/Memo:
收稿日期:2013-04-24。
通讯作者:刘爱连(Email:cjr.1iuailian@vip.163.com)
更新日期/Last Update: 1900-01-01