[1]卢瑞梁,贺小红,蔡华清,等.不同MRI序列检出聚丙烯酰胺水凝胶注射隆乳患者乳腺病变效能的比较研究[J].国际放射医学核医学杂志,2016,40(6):435-441.[doi:10.3760/cma.j.issn.1673-4114.2016.06.007]
　Lu Ruiliang,He Xiaohong,Cai Huaqing,et al.The different MRI sequences to detect breast lesions in polyacrylamide hydrogel injection for augmentation patients: a comparative study[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(6):435-441.[doi:10.3760/cma.j.issn.1673-4114.2016.06.007]
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不同MRI序列检出聚丙烯酰胺水凝胶注射隆乳患者乳腺病变效能的比较研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
40
期数:
2016年第6期
页码:
435-441
栏目:
论著
出版日期:
2016-11-25

文章信息/Info

Title:
The different MRI sequences to detect breast lesions in polyacrylamide hydrogel injection for augmentation patients: a comparative study
作者:
卢瑞梁;  贺小红;  蔡华清;  洪居陆;  冯燕韻;  徐志锋
528000, 广东省佛山市第一人民医院医学影像科MR室
Author(s):
Lu Ruiliang;  He Xiaohong;  Cai Huaqing;  Hong Julu;  Feng Yanyun;  Xu Zhifeng
Department of MRI, Medical Imaging, the First People’s Hospital of Foshan, Foshan 528000, China
关键词:
磁共振成像; 乳腺疾病; 注射隆乳; 聚丙烯酰胺水凝胶; 影像诊断
Keywords:
Magnetic resonance imaging; Breast disease; Injection breast augmentation; Polyacrylamide hydrogel; Diagnostic Imaging
DOI:
10.3760/cma.j.issn.1673-4114.2016.06.007
摘要:
目的 探讨不同MRI序列对聚丙烯酰胺水凝胶（PAHG）注射隆乳后乳腺病变的检出效能。方法 回顾性分析80例临床怀疑合并乳腺病变的注射隆乳患者的MRI影像资料，扫描序列包括T1加权像、T2加权像、短时间反转恢复（STIR）、弥散加权成像（DWI）、MR水成像（MRH）及肝脏容积超快速（LAVA）三维多期动态增强序列，分析各序列图像中病灶的信号特点、位置、形态、大小和数量，以及时间-信号强度曲线，分别计算不同序列对乳腺病变的总检出率和对乳腺癌的诊断准确率。各序列病灶的总检出率差异采用R×C交叉表卡方检验，组内两两比较采用卡方检验分析。结果 160个乳腺中共检出86个病灶，其中乳腺癌病灶30个。T1加权像、T2加权像、STIR、DWI、MRH及LAVA增强序列对乳腺病灶的总检出率分别为32.56%（28/86）、61.11%（53/86）、63.88%（55/86）、41.66%（36/86）、89.53%（77/86）、100%（86/86），其中乳腺癌病灶诊断准确率分别为33.33%（10/30）、66.67%（20/30）、66.67%（20/30）、46.67%（14/30）、100%（30/30）、100%（30/30）。对各序列乳腺病变的总检出率行R×C交叉表卡方检验：χ2=129.428，P<0.05，差异有统计学意义；对各序列乳腺癌病灶诊断准确率行R×C交叉表卡方检验：χ2=51.843，P<0.05，差异有统计学意义。对各序列乳腺病变总检出率和乳腺癌病灶诊断准确率行组内两两比较分析，除T1加权像与MRH、T2加权像与STIR对乳腺病变总检出率的差异无统计学意义外（χ2=1.593、0.100，P均>0.05），其他均有统计学意义（χ2=6.729~87.509，P均<0.05）；而MRH与T1加权像、MRH与T2加权像、MRH与STIR、T2加权像与STIR，以及DWI与LAVA增强序列对乳腺癌诊断准确率的差异均无统计学意义（χ2=1.111、2.443、2.443、0.000、0.000，P均>0.05），其他序列的差异有统计学意义（χ2=12.000~30.000，P均<0.05）。结论 DWI和LAVA增强序列对PAHG注射隆乳后乳腺病变的总检出率最高；合理应用MRI序列，有利于提高乳腺癌病灶的诊断准确率。
Abstract:
Objective To explore the detective values of various MRI sequences in breast polyacrylamide hydrogel(PAHG) injection for augmentation patients. Methods A total of 80 patients who have been injected for augmentation and who have suspected breast lesions were subjected to MRI scanning. The MRI scan sequence included T1 weighted imaging(T1WI), T2 weighted imaging(T2WI), short time inversion recovery(STIR), diffusion weighted imaging(DWI) and MR hydrography(MRH), as well as liver acquisition with valume acceleration(LAVA) dynamic contrast-enhanced sequence. The main sequence analysis indicators included the detection rate of breast disease and breast cancer, and to analyze statistically. Results A total of 86 lesions were observed in 160 breasts. The breast-lesion detection rates of the T1WI, T2WI, STIR, DWI and MRH, as well as LAVA dynamic contrast-enhanced sequence were 32.56%(28/86), 61.11%(53/86), 63.88%(55/86), 41.66%(36/86), 89.53%(77/86), and 100%(86/86), respectively; the breast-cancer detection rates of these sequences were 33.33%(10/30), 66.67%(20/30), 66.67%(20/30), 46.67%(14/30), 100%(30/30), and 100%(30/30), respectively. Each MRI scanning sequence of breast-lesion detection rate of R×C cross-table analysis,χ2=129.428, P<0.05; the difference was statistically significant. Each MRI scanning sequence of breast-cancer detection rate of R×C cross-table analysis,χ2=51.843, P<0.05; the difference was statistically significant. Each MRI scanning sequence detection rate of breast disease and breast cancer in the group were compared pairwise. The detection rates of breast lesions were not statistically significant in T1WI and MRH, T2WI and STIR(χ2=1.593, 0.100,both P>0.05), whereas those in the other scanning sequences were statistically significant(χ2=6.729~87.509,all P<0.05). The differences in breast-cancer detection rates in MRH and T1WI, MRH and T2WI, MRH and STIR, T2WI and STIR, and DWI and LAVA were not statistically significant(χ2=1.111, 2.443, 2.443, 0.000, 0.000,all P>0.05), whereas those of the other sequences were statistically significant(χ2=12.000~30.000,all P<0.05). Conclusions The total detection rate of breast lesions with PAHG injection for augmentation mammoplasty by DWI and LAVA-enhanced sequence wasthe highest. Rational use of MRI sequence will help improve the lesion detection rate of patients’ breast augmentation PAHG injection and has important clinical value.

参考文献/References:

[1] 王蓼, 胡竺, 水淼, 等.MRI对聚丙烯酰胺水凝胶注射隆乳术后并发症的诊断[J].实用放射学杂志, 2012, 28(8):1211-1213. DOI:10.3969/j.issn.1002-1671.2012.08.015.Wang L, Hu Z, Shui M, et al.MR imaging in diagnosing the syndrome of polyacrylamide hydrogel injection for augmentation mammoplasty[J].J Pract Radiol, 2012, 28(8):1211-1213.
[2] 董洁, 田方兴, 唐全.聚丙烯酰胺水凝胶隆乳后无并发症患者生活质量的影响因素[J].中华整形外科杂志, 2013, 29(2):137-139. DOI:10.3760/cma.j.issn.1009-4598.2013.02.015.Dong J, Tian FX, Tang Q.Factors affecting quality of Life of polyacrylamide hydrogel breast augmentation of patients without complications[J].Chin J Plast Surg, 2013, 29(2):137-139.
[3] 邢继平, 赵雨千, 乌兰巴特尔, 等.聚丙烯酰胺水凝胶注射隆乳并发纤维囊内远期血肿一例[J].中华整形外科杂志, 2015, 31(1):71-72. DOI:10.3760/cma.j.issn.1009-4598.2015.01.023.Xing JP, Zhao YQ, Wu LBTE, et al.A case of polyacrylamide hydrogel injection for augmentation with fiber intracapsular hematoma forward[J].Chin J Plast Surg, 2015, 31(1):71-72.
[4] 黄卫平, 林茜茜, 陈瑾, 等.MRI在聚丙烯酰胺水凝胶注射隆乳术后合并乳腺肿瘤中的诊断价值[J].中华整形外科杂志, 2011, 27(2):136-137. DOI:10.3760/cma.j.issn.1009-4598.2011.02.018.Huang WP, Lin QQ, Chen J, et al.The MRI diagnostic value in polyacrylamide hydrogel injection for augmentation surgery with breast tumors[J].Chin J Plast Surg, 2011, 27(2):136-137.
[5] 刘丽华, 龙淼淼, 刘宁, 等.MR扩散加权成像定量诊断聚丙烯酰胺水凝胶隆乳后哺乳期脓肿[J].实用放射学杂志, 2015, 31(4):683-685. DOI:10.3969/j.issn.1002-1671.2015.04.045.Liu LH, Long MM, Liu N, et al.Quantitative analysis of diffusion weighted imaging for diagnosis of puerperal breast abscess after polyacrylamide hydrogel augmentation mammoplasty[J].J Pract Radiol, 2015, 31(4):683-685.
[6] 李刚, 苏顺清, 覃达贤, 等.MRI在聚丙烯酰胺水凝胶注射隆乳术后并发症的诊断价值[J].中国临床医学影像杂志, 2013, 24(4):247-250. DOI:10.3969/j.issn.1008-1062.2013.04.007.Li G, Su SQ, Qin DX, et al.MRI in the diagnosis of complications due to breast augmentation with polyacrylamide hydrogel[J].J Chin Clin Med Imaging, 2013, 24(4):247-250.
[7] Leung KM, Yeoh GP, Chan KW.Breast pathology in complications associated with polyacrylamide hydrogel(PAAG) mammoplasty[J].Hong Kong Med J, 2007, 13(2):137-140.
[8] Christensen LH, Breiting VB, Aasted A, et al.Long-term effects of polyacrylamide hydrogel on human breast tissue[J].Plast Reconstr Surg, 2003, 111(6):1883-1890. DOI:10.1097/01.PRS.0000056873.87165.5A.
[9] Bello G, Jackson IT, Keskin M, et al.The use of polyacrylamide gel in soft tissue augmentation:an experimental assessment[J].Plast Reconstr Surg, 2007, 119(4):1326-1336. DOI:10.1097/01.prs.0000254824.13065.3b.
[10] Ben Khedher N, David J, Trop I, et al.Imaging findings of breast augmentation with injected hydrophilic polyacrylamide gel:Patient reports and literature review[J].Eur J Radiol, 2011, 78(1):104-111. DOI:10.1016/j.ejrad.2009.09.021.
[11] Qiao Q, Wang XC, Sun JM, et al.Management for postoperative complications of breast augmentation by injected polyacrylamide hydrogel[J].Aesthetic Plast Surg, 2005, 29(3):156-161. DOI:10.1007/s00266-004-0099-0.
[12] Teo SY, Wang SC.Radiologic features of polyacrylamide gel mammoplasty[J/OL].AJR Am J Roentgenol, 2008, 191(3):W89-95[2016-08-28].https:www.ncbi.nlm.nih.gov/pubmed/?term=18716084. DOI:10.2214/AJR.07.3616.
[13] Unal O, Koparan HI, Avcu S, et al.The diagnostic value of diffusion-weighted magnetic resonance imaging in soft tissue abscesses[J].Eur J Radiol, 2011, 77(3):490-494. DOI:10.1016/j.ejrad.2009.08.025.
[14] 卢瑞梁, 蔡华清, 周新韩, 等.聚丙烯酰胺水凝胶注射隆乳术后MR容积再现技术的应用与探讨[J].中国美容整形外科杂志, 2011, 22(12):737-739. DOI:10.3969/j.issn.1673-7040.2011.12.011.Lu RL, Cai HQ, Zhou XH, et al.Application and investigate of Mr volume rendering technology after augmentation mammoplasty with polyacrylamide hydrogel injection[J].Chin J Aesth Plast Surg, 2011, 22(12):737-739.

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备注/Memo

备注/Memo:
收稿日期:2016-08-29。
基金项目:佛山市医学类科技攻关项目（2014AB00293）；佛山市科技创新专项（2015AG10004）
通讯作者:卢瑞梁,Email:luruiliang126@126.com
更新日期/Last Update: 1900-01-01