[1]马文超,徐文贵.11C-乙酸盐在肿瘤PET或PET-CT中的应用[J].国际放射医学核医学杂志,2011,35(1):23-27.[doi:10.3760/cma.j.issn.1673-4114.2011.01.007]
 MA Wen-chao,XU Wen-gui.The application of 11C-acetate PET or PET-CT for tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(1):23-27.[doi:10.3760/cma.j.issn.1673-4114.2011.01.007]
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11C-乙酸盐在肿瘤PET或PET-CT中的应用(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第1期
页码:
23-27
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
The application of 11C-acetate PET or PET-CT for tumors
作者:
马文超 徐文贵
天津医科大学附属肿瘤医院分子影像及核医学诊疗科, 天津 300060
Author(s):
MA Wen-chao XU Wen-gui
Deportment of Molecule Image and Nuclear Medicine to Diagnose and Treat, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
关键词:
乙酸盐类碳放射性同位素肿瘤正电子发射断层显像术体层计算机X线计算机
Keywords:
AcetatesCarbon radioisotopesNeoplasmsPositron-emssion tomographyTomographyX-ray computed
DOI:
10.3760/cma.j.issn.1673-4114.2011.01.007
摘要:
18F-FDG是临床上应用最多、范围最广的正电子显像剂,但其对于某些肿瘤的诊断缺乏敏感性和特异性。11C-乙酸盐与18F-FDG相比,有不同的体内分布方式及细胞摄取机制,是近年来众多研究证实很有希望在某些方面弥补18F-FDG显像不足的正电子显像剂。该文综述了目前11C-乙酸盐PET或PET-CT的机制、研究领域及最新进展。
Abstract:
18F-FDG is generally used for tumors’PET, and it is the most and widest useful positron radiopharmaceutical in the clinic. But it does not have enough sensitivity and specificity for some kinds of tumors. 11C-acetate has different distribution in body and uptaken mechanism by cell from 18F-FDG. Many studies have confirmed that 11C-acetate has the potential value to make up the insufficiency of 18F-FDG. The researches on 11C-acetate PET or PET-CT are reviewed in this paper, including the mechanism, research area and the newest progress.

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备注/Memo

备注/Memo:
收稿日期:2010-11-26。
基金项目:天津市自然科学基金重点项目(08JCZDJC23700);天津市高等学校科技发展基金(20080133)
通讯作者:徐文贵(Email:wenguixy@tom.com)
更新日期/Last Update: 1900-01-01