[1]乌海飞,尹红燕,刘帅,等.胰岛β细胞的分子核医学显像进展[J].国际放射医学核医学杂志,2010,34(4):203-205.[doi:10.3760/cma.j.issn.1673-4114.2010.04.003]
　WU Hai-fei,YIN Hong-yan,LIU Shuai,et al.Progress in molecular nuclear medicine imaging of pancreatic beta cells[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(4):203-205.[doi:10.3760/cma.j.issn.1673-4114.2010.04.003]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第4期
页码:
203-205
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Progress in molecular nuclear medicine imaging of pancreatic beta cells
作者:
乌海飞;  尹红燕;  刘帅;  张一帆
200025, 上海交通大学医学院附属瑞金医院核医学科
Author(s):
WU Hai-fei;  YIN Hong-yan;  LIU Shuai;  ZHA NG Yi-fan
Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
关键词:
糖尿病; 胰岛素分泌细胞; 正电子发射断层显像术
Keywords:
Diabetes mellitus; Insulin-secreting cell; Positron-emission tomography
DOI:
10.3760/cma.j.issn.1673-4114.2010.04.003
摘要:
糖尿病是严重威胁人类健康的常见病和多发病。糖尿病主要是由于胰岛β细胞选择性破坏或胰岛e细胞分泌胰岛素迟缓和胰岛素抵抗而使胰岛素相对不足所致。β细胞的数量只有减少50%~60%时才会出现相关的症状。由于胰腺位置较深,β细胞含量少,目前临床诊断主要采用有创性方法,且难于进行早期诊断。因此,通过无创性的方法进行β细胞相关代谢疾病的早期诊断,越来越受到人们的关注,影像学诊断也就成了关注焦点,但是如何进行β细胞数量和功能的评估仍是目前影像学诊断面临的重要课题。
Abstract:
Diabetes mellitus is a common and frequently occurring disease which seriously threaten the health of human beings. Type 1 and type 2 diabetes respectively results from being destroyed and insufficient beta-cell mass. The associated symptoms appear until 50%-60% decrease of beta-cell mass. Because pancreas is deeply located in the body, with few beta-cell mass, the current methods of clinical diagnosis are invasive and late. So diagnosis of metabolism disease of beta-cell early and non-invasively becomes more and more popular, imaging diagnosis of diabetes mellitus becomes the focus of researches, but how to estimate the mass of beta-cell is still an important subject in imaging technology.

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备注/Memo

备注/Memo:
收稿日期:2010-04-11。
基金项目:上海市教委重点学科建设基金(S30203)
通讯作者:张一帆,E-mail:shangyifan1992@yehoo.com.cn
更新日期/Last Update: 1900-01-01