[1]俞丹,许林,洪明,等.99Tcm-硫胶体及其联合染色法对早期乳腺癌前哨淋巴结探测的比较[J].国际放射医学核医学杂志,2011,35(5):281-284.[doi:10.3760/cma.j.issn.1673-4114.2011.05.007]
　YU Dan,XU Lin,HONG Ming,et al.Comparison of radioactive sulfur colloid and combined methylene blue injection methods for detection of sentinel lymph node in early breast cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(5):281-284.[doi:10.3760/cma.j.issn.1673-4114.2011.05.007]
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99Tcm-硫胶体及其联合染色法对早期乳腺癌前哨淋巴结探测的比较(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第5期
页码:
281-284
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Comparison of radioactive sulfur colloid and combined methylene blue injection methods for detection of sentinel lymph node in early breast cancer
作者:
俞丹1;  许林2;  洪明2;  吴华1;  苏新辉1;  陈贵兵1
1. 厦门大学附属第一医院核医学科, 厦门 361003;
2. 厦门大学附属第一医院肿瘤外科, 厦门 361003
Author(s):
YU Dan1;  XU Lin2;  HONG Ming2;  WU Hua1;  SU Xin-hui1;  CHEN Gui-bin1
Department of Nuclear Medicine, First Hospital Affiliated to Xiamen University, Xiamen 361003, China
关键词:
乳腺肿瘤; 前哨淋巴结活组织检查; 硫胶体; 亚甲蓝
Keywords:
Breast neoplasms; Sentinel lymph node biopsy; Sulfur colloid; Methylene blue
DOI:
10.3760/cma.j.issn.1673-4114.2011.05.007
摘要:
目的 评价单用99Tcm-硫胶体和99Tcm-硫胶体与亚甲蓝联合应用探测早期乳腺癌前哨淋巴结(SLN)的效能。方法 76例早期乳腺癌患者分为单用99Tcm-硫胶体组(25例)和99Tcm-硫胶体与亚甲蓝联合组(51例),分别在术前进行乳腺癌SLN探测,以腋窝淋巴结病理检查结果作为评价标准。结果 76例患者中成功探测到SLN 74例,SLN的检出率、准确率、灵敏度和假阴性率在99Tcm-硫胶体组分别为92.0%、95.7%、90.0%、10.0%;在联合组分别为100%、98.0%、95.2%、4.8%。结论 乳腺癌SLN探测可较准确预测腋窝淋巴结的转移状况,为外科医生确定手术方式提供重要信息,联合应用99Tcm-硫胶体和亚甲蓝可提高SLN的检出率和准确率,降低假阴性率。
Abstract:
Objective To compare the efficacy of 99Tcm-sulfur colloid and combined 99Tcm-sulfur colloid/methylene blue methods for detection of sentinel lymph node(SLN) in early breast cancer. Methods Seventy-six patients with early breast cancer were dived into two groups. In group 1(n=25), 99Tcm-sulfur colloid detection was used alone. In group 2(n=51), both 99Tcm-sulfur colloid detection and methylene blue methods were used. The pathological findings of resected axillary lymph nodes were regarded as evaluation standard. Results In 76 patients SLN was successfully detected in 74 cases. The SLN detection rate, accuracy, sensitivity and the false negative rate for 99Tcm-sulfur colloid group and combined group were 92.0% vs. 100%, 95.7% vs. 98.0%, 90.0% vs. 95.2%, and 10.0% vs. 4.8% respectively. Conclusions SLN detection in early breast cancer may accurately predict axillary lymph node metastasis, thus providing important information for surgery. Combined use of 99Tcm-sulfur colloid and methylene blue methods may improve the SLN detection accuracy and reduce false negative rate.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2011-06-21。
通讯作者:俞丹(Email:yd69168@yahoo.com.cn)
更新日期/Last Update: 1900-01-01