[1]亓龙,王辉.甲状腺癌骨转移模型的研究[J].国际放射医学核医学杂志,2010,34(6):329-332.[doi:10.3760/cma.j.issn.1673-4114,2010.06.003]
 QI Long,WANG Hui.Research progress of animal model of bone metastases of thyroid carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(6):329-332.[doi:10.3760/cma.j.issn.1673-4114,2010.06.003]
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甲状腺癌骨转移模型的研究(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第6期
页码:
329-332
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Research progress of animal model of bone metastases of thyroid carcinoma
作者:
亓龙 王辉
上海交通大学医学院附属新华医院核医学科, 200092
Author(s):
QI Long WANG Hui
Department of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai 200092, China
关键词:
甲状腺肿瘤肿瘤转移模型动物
Keywords:
Thyroid neoplasmsNeoplasm metastasisModelsanimal
DOI:
10.3760/cma.j.issn.1673-4114,2010.06.003
摘要:
甲状腺癌是内分泌系统最常见的恶性肿瘤,其发病率逐年上升,虽然该病预后较好,但若发生骨转移,患者10年生存率将明显降低。目前,甲状腺癌发生骨转移的机制尚不明确,对甲状腺癌骨转移的研究不仅具有重要的临床价值,也有很重要的科研价值。甲状腺癌骨转移动物模型的建立是研究甲状腺癌骨转移机制和治疗的基础,根据其建立方法可分为自发性、化学诱导性、转基因诱导性和移植性4种。
Abstract:
Thyroid carcinoma is the most common endocrine malignancy, its incidence rate increases year by year. Although the disease has good prognosis, if bone metastases happen, 10-year survival rate of patients will obviously reduce. At present, the mechanism of the occurrence of bone metastases is not clear.The research of bone metastases of thyroid carcinoma not only has important clinical value, but also scientific value. Animal model of bone metastasis of thyroid carcinoma is the basis to study the mechanism and therapy of thyroid carcinoma. According to its establishment methods, it can be divided into four types, including spontaneous type, chemical induced type, transgenic induced type and transplanted type.

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备注/Memo

备注/Memo:
收稿日期:2010-08-22。
通讯作者:王辉(E-mail:wanghuishanghai@hotmail.com)
更新日期/Last Update: 1900-01-01