[1]杜晓光,闫志华,孟玉葆.562例原发肺癌患者核素骨显像结果分析[J].国际放射医学核医学杂志,2009,33(6):346-348.[doi:10.3760/cma.j.issn.1673-4114.2009.06.008]
 DU Xiao-guang,YAN Zhi-hua,MENG Yu-bao.Analysis of bone imaging results of 562 primary lung carcinoma patients[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(6):346-348.[doi:10.3760/cma.j.issn.1673-4114.2009.06.008]
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562例原发肺癌患者核素骨显像结果分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第6期
页码:
346-348
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Analysis of bone imaging results of 562 primary lung carcinoma patients
作者:
杜晓光 闫志华 孟玉葆
郑州大学第一附属医院核医学科, 郑州 450052
Author(s):
DU Xiao-guang YAN Zhi-hua MENG Yu-bao
Department of Nuclear Medicine, the First Affiliated Hospital of Zhengshou University, Zhengzhou 450052, China
关键词:
肺肿瘤99锝美罗酸盐放射性核素显像肿瘤转移
Keywords:
Lung neoplasmsTechnetium Tc 99m medronateRadionuclide imagingNeoplasm metastasis
DOI:
10.3760/cma.j.issn.1673-4114.2009.06.008
摘要:
目的 通过核素骨显像检查,探讨不同病理组织学类型肺癌的骨转移规律。方法 对562例已确诊的原发肺癌患者进行99Tcm-亚甲基二膦酸盐(99Tcm MDP)全身骨显像,对骨显像的结果和肺癌病理类型进行回顾性分析。结果 各类型肺癌骨转移平均发生率为43.06%,肺腺癌和小细胞癌骨转移率较高,分别为55.43%和45.16%,腺鳞癌、鳞癌骨转移发生率分别为37.93%和35.19%。结论 肺癌骨转移发生率较高,肺腺癌和小细胞癌较其他类型肺癌更易发生骨转移;核素全身骨显像是诊断肺癌早期骨转移的首选方法,对帮助判断疾病的进展程度,选择合适的治疗方案,改善患者的生存质量和延长生命有重要的临床意义。
Abstract:
Objective To evaluate regularity of bone metastasis with bone imaging in different histological types of lung cancer patients. Methods 99Tcm-methytene diphosphonate(99Tcm-MDP) whole body bone imaging was performed in 562 patients who had been diagnosed primary lung cancer. The bone imaging results of different pathological types of lung cancer were analyzed. Results Average incidence rate of bone metastasis in all types of lung cancer is 43.06%. Pulmonary adenocarcinoma and small cell carcinoma has higher incidence rate, 45.16% and 55.4% respectively. Incidence rate of bone metastasis in adenosquamous carcinoma and squamous cell carcinoma were 37.93% and 35.19% respectively, less than that of adenocarcinoma and small cell carcinoma. Conclusion The incidence rate of bone metastasis of lung cancer is higher, lung adenocarcinoma and small cell carcinoma are more susceptible to metastasis to bones.Radionuclide whole body bone imaging is the preferred method for early diagnosis of bone metastasis, and helps judge the progress of disease, select appropriate treatment programs, improve the patients live quality and prolong life expectancy.

参考文献/References:

[1] 李玉林.病理学.6版.北京:人民卫生出版社,2003:182.
[2] Mundy GR.Metastasis to bone:causes,consequences and therapeutic opportunities.Nat Rev Cancer,2002,2(8):584-593.
[3] 殷蔚伯,谷铣之.肿瘤放射治疗学.3版.北京:中国协和医科大学出版社,2002:1088-1091.
[4] 朱军,卞秀华,梅泽如,等.肺癌骨转移的诊断及放疗止痛治疗.中国肿瘤临床与康复,1999,6(2):77-78.
[5] 陈志宵,周道安.34例原发性肺癌骨转移临床相关因素分析.中国肿瘤,2006,15(12):873-875.
[6] Roodman GD.Mechanisms of bone metastasis.N Engl J Med,2004,350(16):1655-1664,
[7] 邓智勇,杨波,卢汝红.278例骨转移癌与骨痛分析.临床医学,2005,25(12):38-39
[8] 林学德,张晶.肺癌骨转移的临床特点分析.中国肿瘤临床与康复,2000,7(5):38-39.
[9] 李少林.核医学.6版.北京:人民卫生出版社,2004:131.
[10] 李舰南,尚玉琨,蔡良,等.130例脊柱疾病核素骨显像与MRI、CT、X线诊断的比较研究.脊柱外科杂志,2004,2(3):142-145.

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备注/Memo

备注/Memo:
收稿日期:2009-04-27。
通讯作者:闰志华(E-mail:duxiaoguan9763@gmail.com)
更新日期/Last Update: 1900-01-01