[1]毛奇琦,孙旭,严惟力.13C呼气试验:一种有益的消化系统疾病检测方法[J].国际放射医学核医学杂志,2009,33(3):129-132.[doi:10.3760/cma.j.issn.1673-4114.2009.03.001]
 MAO Qi-qi,SUN Xu,YAN Wei-li.13C-breath test: a practical diagnostic stool in gastroenterology[J].International Journal of Radiation Medicine and Nuclear Medicine,2009,33(3):129-132.[doi:10.3760/cma.j.issn.1673-4114.2009.03.001]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
33
期数:
2009年第3期
页码:
129-132
栏目:
核医学诊断
出版日期:
1900-01-01

文章信息/Info

Title:
13C-breath test: a practical diagnostic stool in gastroenterology
作者:
毛奇琦1 孙旭1 严惟力2
1. 复旦大学附属华山医院消化科, 上海 200040;
2. 交通大学医学院附属仁济医院核医学科, 上海 200127
Author(s):
MAO Qi-qi1 SUN Xu1 YAN Wei-li2
1. Department of Digestive Internal Medicine, Huashan Hospital of Fudan University, Shanghai 200040, China;
2. Depsrtment of Nuclear Medicine, Renji Hospital, Shanghai Jiaotong University School of Medicine
关键词:
螺杆菌幽门胃排空肝功能试验13C呼气试验
Keywords:
Helicobacter pyloriGastric emptyingLiver function testsl3C-breath lest
DOI:
10.3760/cma.j.issn.1673-4114.2009.03.001
摘要:
稳定性核素13C呼气试验作为一种安全、简便、无创的检查,可以对脏器功能进行实时定量的评价,具有一定的敏感性和特异性,日益受到临床医生青睐。该文综述罔内外13C呼气试验在消化系统疾病诊断领域的应用研究进展及其局限性,并对其发展作一展望。
Abstract:
As a stable isotope, 13C-breath test provide a non-invasive method to quantitatively assess organ functions. It is relatively simple to take 13C-breath test, which have good sensitivity and specificity. This review is aimed at providing advance in research of 13C-breath test and looking into the future of the art.

参考文献/References:

[1] Braden B, Lembcke B, Kuker W, et al. 13C-breath tests:current state of the art and future directions. Dig Liver Dis, 2007, 39(9):795-805.
[2] Hirschl AM, Makristathis A. Methods to detect Helicobacter pylori:from culture to molecular biology. Helicobacter, 2007, 12(Suppl 2):6-11.
[3] Rieei C, Holton J, Vaira D, Diagnosis of Helicobaeter pylori:invasive and non-invasive tests. Best Pratt Res Clin Gastroenterol, 2007, 21(2):299-313.
[4] Sanaka M, Yamamuto T, Nakayama S, et al. Reliability of the time to maximal [13CO2]excretion and the half-[13CO2]exeretion time as a gastric emptying parameter:assessments using the Wagner-Nelsun method. J Smooth Muscle Res, 2007, 43(5):201-209.
[5] Usai Satta P, Searpa M, Oppia F, et al.13C-octanoic acid breath test in functional and organic disease:critieal review of literature. Eur Rev Med Pharmaeol Sei, 2005, 9(5 Suppl 1):9-13.
[6] Sanaka M, Yamamoto T, Kuyama Y. Retention, fixation, and loss of the [13C]label:a review for the understanding of gastric emptying breath tests. Dig Dis Sci, 2008, 53(7):1747-1756.
[7] Braden B, Faust D, Sarrazin U, et al. 13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection. Aliment Pharmaeol Ther, 2005, 21(2):179-185.
[8] Lalazar G, Pappo O, Hershcovici T, et al. A continuous (13)C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT. J Viral Hepat, 2008, 15(10):716-728.
[9] Ocker M, Ganslmayer M, Zopf S, et al. Improvement of quantitative testing of liver function in patients with chronic hepatitis C after installment of antiviral therapy. World J Gastroenterol, 2005, 11(35):5521-5524.
[10] Ilan Y. Review article:the assessment of liver function using breath tests. Aliment Pharmaeol Ther, 2007, 26(10):1293-1302.

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备注/Memo

备注/Memo:
收稿日期:2009-01-21
基金项目:国家自然科学基金(30770599);中国博士后科学基金(2005038143);上海市教委科研创新项目(09YZ82)
通讯作者:严惟力,E-mail:yan_weili@126.com
更新日期/Last Update: 1900-01-01