[1]孙昱,刘兴党.13C标记试剂在消化系统疾病诊断中的研究进展[J].国际放射医学核医学杂志,2014,38(5):323-327.[doi:10.3760/cma.j.issn.1673-4114.2014.05.011]
　Sun Yu,Liu Xing-dang.The research progress of 13C-labeled substrates in the diagnosis of digestive system disease[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(5):323-327.[doi:10.3760/cma.j.issn.1673-4114.2014.05.011]
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13C标记试剂在消化系统疾病诊断中的研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
38
期数:
2014年第5期
页码:
323-327
栏目:
出版日期:
2014-09-25

文章信息/Info

Title:
The research progress of 13C-labeled substrates in the diagnosis of digestive system disease
作者:
孙昱;  刘兴党
复旦大学附属华山医院核医学科, 上海, 200040
Author(s):
Sun Yu;  Liu Xing-dang
Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
关键词:
螺杆菌; 幽门; 消化系统疾病; 碳同位素; 尿素呼气实验
Keywords:
Helicobacter pylori; Digestive system disease; Carbon isotopes; Urea breath test
DOI:
10.3760/cma.j.issn.1673-4114.2014.05.011
摘要:
13C是稳定性核素,其标记的诊断试剂已逐渐应用于临床,尤其是13C标记的尿素呼气实验,其被广泛用于胃幽门螺旋杆菌感染的诊断。13C标记的其他化合物如氨基比林、美沙西丁、辛酸、混合甘油三酯等还可用于消化系统中其他疾病的诊断。由于13C标记的诊断试剂具有无创、安全、无辐射的特点,其适用于儿童、孕妇等患者,已受到越来越多学者的关注,该文对近几年13C在消化系统疾病诊断方面的研究进展作一综述。
Abstract:
13C is a stable nuclide and its labeled substrates have already used in clinic. Among the substrates, 13C-urea is the mainstream of clinical practice to diagnose the Helicobacter pylori. The other substrates such as aminopyrine, methacetin, octanoic and mixed triglyceride are used to diagnose dis-eases of the digestive system. Because the 13C-labeled compounds are non-invasive, safe, nonradiative and suitable for pregnant women and children, so many researchers focus on them. This paper makes a review on the research progress of 13C-labeled substrates in the diagnosis of digestive system disease in recent years.

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备注/Memo

备注/Memo:
收稿日期:2014-04-09。
通讯作者:刘兴党(Email:xingdliu@yahoo.com)
更新日期/Last Update: 1900-01-01