[1]陈璟,吴华.乳腺癌前哨淋巴结探查的研究进展[J].国际放射医学核医学杂志,2002,26(5):222-224.
　CHEN Jing,WU Hua.Sentinel lymph node detection in breast cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(5):222-224.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
26
期数:
2002年第5期
页码:
222-224
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Sentinel lymph node detection in breast cancer
作者:
陈璟;  吴华
430030 武汉, 华中科技大学同济医学院附属同济医院
Author(s):
CHEN Jing;  WU Hua
Department of Nuclear Medicine, Tongji Hospital, Huazhong University of Science and Technology, Hubei Wuhan 430030, China
关键词:
乳腺癌; 前哨淋巴结; 放射性核素显像
Keywords:
breast cancer; sentinellymph node; lymphoscintigraphy
分类号:
R817.4
摘要:
乳腺癌前哨淋巴结(sentinel lymph node, SLN)是乳腺癌淋巴转移通道中最先经历的第一级淋巴结。通过乳腺癌SLN预测乳腺癌区域淋巴结转移状况,为乳腺癌的准确分期和外科手术提供了重要的依据。根据示踪剂的不同,有两种方法可以探查乳腺癌SLN,其中使用放射性核素标记物作为示踪剂探查乳腺癌SLN是目前较具优势的方法,且不同于传统的淋巴显像;乳腺癌SLN探查的成功率受到诸多因素的影响,其探查技术亦需进一步的研究来提高。
Abstract:
The concept of sentinel lymph node (SLN)holds that the lymphatic effluent of a tumor drains initially to one or two lymph nodes before other nodes receive the tumoral drainage.It is a great advance in breast cancer surgery to one or two lymph nodes before other nodes receive the tumoral drainage.It is a great advance in breast cancer surgery to predict regional nodal metastases by sentinel lymph node detection in breast cancer,which can give the more refinedstaging of breast cancer.According to the different tracers,there are two ways to detect SLN.Using a radiopharmaceutical to identify SLN in breast cancer is superior,and differs from traditional lymphoscintigraphy.Some factors could affect SLN detection in breast cancer,and many efforts should be taken to improve SLN detection techniques.

参考文献/References:

[1] McGuckin MA, Cummings MC, Walsh MD, et al. Occult axillary node metastases in breast cancer:their detection and prognostic significance[J]. Br J Cancer, 1996, 73(1):88-95.
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[3] Borgstein PJ, Pijpers R, Comans EF, et al. Sentinel node biopsy in breast cancer:Guidelines and pitfalls of lymphoscintigraphy and gamma probe detection[J]. J Am Coll Surg, 1998, 186(3):275-283.
[4] Haffty BG, Ward B, Pathare P, et al. Reappraisal of the role of axillary lymph node dissection in the conservative treastment of breast cancer[J]. J Clin Oncol, 1997, 15(2):691-700.
[5] Glass EC, Essner R, Giuliano AE. Sentinel node localization in breast cancer[J]. Semin Nucl Med, 1999, 29(1):57-68.
[6] Giuliano AE, Jones RC, Brennan M, et al. Sentinel lymphadenectomy in breast cancer[J]. J Clin Oncol, 1997, 15(6):2345-2350.
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[8] D’Eredita G, Serio G, Mele M, et al. Effect of the use of vital dye, lymphoscintigraphy, or a combination for axillary lymphatic mapping and sentinel node biopsy in breast cancer[J]. World J Surg, 2002, 26(5):592-597.

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备注/Memo

备注/Memo:
收稿日期:2001-09-28。
作者简介:陈璟(1973-),女,湖北沙市人,核医学科主治医师,博士研究生,主要从事临床核医学研究;吴华(1958-),男,湖北通山人,核医学科主任医师,教授,博士生导师。
更新日期/Last Update: 1900-01-01