[1]江涛,陈跃.放射性核素显像在肺吸入诊断中的应用进展[J].国际放射医学核医学杂志,2015,39(2):165-169.[doi:10.3760/cma.j.issn.1673-4114.2015.02.014]
 Jiang Tao,Chen Yue.Advances in radionuclide imaging for pulmonary aspiration[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(2):165-169.[doi:10.3760/cma.j.issn.1673-4114.2015.02.014]
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放射性核素显像在肺吸入诊断中的应用进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
39
期数:
2015年第2期
页码:
165-169
栏目:
出版日期:
2015-03-25

文章信息/Info

Title:
Advances in radionuclide imaging for pulmonary aspiration
作者:
江涛 陈跃
四川泸州医学院附属医院核医学科, 646000
Author(s):
Jiang Tao Chen Yue
Department of Nuclear Medicine, Affiliated Hospital, Luzhou Medical College, Luzhou 646000, China
关键词:
肺炎吸入性唾液显像胃食管反流显像吞咽显像
Keywords:
Pulmonary aspirationSalivagramGastroesophageal reflux scintigraphyPharyngeal scintigraphy
DOI:
10.3760/cma.j.issn.1673-4114.2015.02.014
摘要:
肺吸入是常见的呼吸系统疾病,因其缺少典型的临床症状,常常直到造成严重的肺损伤时才被发现,其发病率和病死率较高。因此,早期诊断肺吸入至关重要。肺吸入的发生机制复杂多样,临床特征不典型,又因对其缺少特异的诊断技术与方法,以致延误诊断和治疗时机的患者不在少数。在欧美国家,放射性核素显像是临床上诊断肺吸入的常用方法,但在国内相关的研究报道较少,笔者就放射性核素显像在肺吸入诊断中的进展作一综述。
Abstract:
Pulmonary aspiration is a common disease of respiratory system. The morbidity and mortality of the disease is high since it lacks typical clinical symptoms and generally can hardly be detected until severe lung damages caused. Consequently, early diagnosis of pulmonary aspiration is of vital importance. The pathogenetic mechanism of pulmonary aspiration is complicated and diverse. Since its clinical features are not atypical and specific diagnostic method is not available, there are lots of patients delayed in diagnosis and treatment. In the European and American countries, radionuclide imaging is the most commonly used clinical method for pulmonary aspiration diagnosis. However, there are few related researches and reports in China. The writer has summarized the progress of radionuclide imaging for pulmonary aspiration diagnosis.

参考文献/References:

[1] Marik PE. Pulmonary aspiration syndromes[J]. Curr Opin Pulm Med, 2011, 17(3):148-154.
[2] Lanspa MJ, Jones BE, Brown SM, et al. Mortality, morbidity, and disease severity of patients with aspiration pneumonia[J]. J Hosp Med, 2013, 8(2):83-90.
[3] Saad K, Mohamed SA, Metwalley KA. Recurrent/persistent pneu-monia among children in upper Egypt[J/OL]. Mediterr J Hematol Infect Dis, 2013, 5(1):e2013028[2014-10-20]. http://www.mjhid.org/article/view/2013.028.
[4] Rossi UG, Owens CM. The radiology of chronic lung disease in chil-dren[J]. Arch Dis Child, 2005, 90(6):601-607.
[5] Boesch RP, Daines C, Willging JP, et al. Advances in the diagnosis and management of chronic pulmonary aspiration in children[J]. Eur Respir J, 2006, 28(4):847-861.
[6] Donzelli J, Brady S, Wesling M, et al. Effects of the removal of the tracheotomy tube on swallowing during the fiberoptic endoscopic exam of the swallow(FEES)[J]. Dysphagia, 2005, 20(4):283-289.
[7] Da Silva AP, Lubianca Neto JF, Santoro PP. Comparison between videofluoroscopy and endoscopic evaluation of swallowing for the diagnosis of dysphagia in children[J]. Otolaryngol Head Neck Surg, 2010, 143(2):204-209.
[8] Lin CW, Chang YC, Chen WS, et al. Prolonged swallowing time in dysphagic parkinsonism patients with aspiration pneumonia[J]. Arch Phys Med Rehabil, 2012, 93(11):2080-2084.
[9] Terre R, Mearin F. Resolution of tracheal aspiration after the acute phase of Stroke-Related oropharyngeal dysphagia[J]. Am J Gas-troenterol, 2009, 104(4):923-932.
[10] Zammit-Maempel I, Chapple CL, Leslie P. Radiation dose in vide-ofluoroscopic swallow studies[J]. Dysphagia, 2007, 22(1):13-15.
[11] Heyman S, Respondek M. Detection of pulmonary aspiration in children by radionuclide "salivagram"[J]. J Nucl Med, 1989, 30(5):697-699.
[12] Gleeson K, Eggli DF, Maxwell SL. Quantitative aspiration during sleep in normal subjects[J]. Chest, 1997, 111(5):1266-1272.
[13] Tei K, Takinami S, Yamazaki Y, et al. Scintigraphic method to de-tect silent aspiration during sleep in postsurgical patients with oral cancer[J]. Head Neck, 2003, 25(3):245-250.
[14] Beal M, Chesson A, Garcia T, et al. A pilot study of quantitative as-piration in patients with symptoms of obstructive sleep apnea:Comparison to a historic control group[J]. Laryngoscope, 2004, 114(6):965-968.
[15] Baikie G, Reddihough DS, South M, et al. The salivagram in severe cerebral palsy and able-bodied adults[J]. J Paediatr Child Health, 2009, 45(6):342-345.
[16] Kang Y, Chun MH, Lee SJ. Evaluation of salivary aspiration in brain-injured patients with tracheostomy[J]. Ann Rehabil Med, 2013, 37(1):96-102.
[17] 何小文. 放射性核素唾液显像与牛奶示踪扫描探查肺误吸的对照研究[J]. 放射学实践, 2005, 20(4):348-348.
[18] 杨吉刚, 李春林, 邹兰芳, 等.胃食管反流显像和唾液吸入显像在儿科肺吸入中的应用[J]. 首都医科大学学报, 2013, 34(1):18-22.
[19] 陈萍, 侯鹏, 郑则广, 等. 99Tcm-硫胶体唾液显像方法学建立及在成年呼吸道疾病患者误吸中的应用[J]. 中华核医学与分子影像杂志, 2013, 33(3):192-194.
[20] Baikie G, South MJ, Reddihough DS, et al. Agreement of aspiration tests using Barium videofluoroscopy, salivagram, and milk scan in children with cerebral palsy[J]. Dev Med Child Neurol, 2005, 47(2):86-93.
[21] Somasundaram VH, Subramanyam P, Palaniswamy S. Salivagram revisited:justifying its routine use for the evaluation of persistent/recurrent lower respiratory tract infections in developmentally nor-mal children[J]. Ann Nucl Med, 2012, 26(7):578-585.
[22] Simons JP, Rubinstein EN, Mandell DL. Clinical predictors of aspi-ration on radionuclide salivagrams in children[J]. Arch Otolaryngol Head Neck Surg, 2008, 134(9):941-944.
[23] Jang DH, Choi KH, Kim DH, et al. Comparison between the ra-dionuclide salivagram and videofluoroscopic swallowing study methods for evaluating patients with aspiration pneumonia[J]. Ann Nucl Med, 2013, 27(3):247-252.
[24] Park HW, Lee WY, Park GY, et al. Salivagram after gland injection of botulinum neurotoxin a in patients with cerebral infarction and cerebral palsy[J]. PM R, 2012, 4(4):312-316.
[25] Drubach LA, Zurakowski D, Palmer IE, et al. Utility of salivagram in pulmonary aspiration in pediatric patients:comparison of sali-vagram and chest radiography[J]. AJR Am J Roentgenol, 2013, 200(2):437-441.
[26] 陈跃, Zhuang H, 杨吉刚. 放射性核素唾液显像的临床应用进展[J]. 国际放射医学核医学杂志, 2012, 36(1):13-15.
[27] Heyman S, Kirkpatrick JA, Winter HS, et al. An improved ra-dionuclide method for the diagnosis of gastroesophageal reflux and aspiration in children(milk scan)[J]. Radiology, 1979, 131(2):479-482.
[28] Othman S. Gastroesophageal reflux studies using milk in infants and children-the need for multiple views[J]. Nucl Med Commun, 2011, 32(10):967-971.
[29] Songur N, Songur Y, Suereyya S, et al. Gastroesophageal scintigra-phy in the evaluation of adult patients with chronic cough due to gastroesophageal reflux disease[J]. Nucl Med Commun, 2008, 29(12):1066-1072.
[30] Ravelli AM, Panarotto MB, Verdoni L, et al. Pulmonary aspiration shown by scintigraphy in gastroesophageal reflux-related respiratory disease[J]. Chest, 2006, 130(5):1520-1526.
[31] Gouvea A, Costa MS, Aldighieri FC, et al. Evaluation of the useful-ness of assessing pulmonary aspiration in a gastroesophageal reflux scintigraphy study[J]. Rev Assoc Med Bras, 2007, 53(3):257-260.
[32] Galli J, Valenza V, D’alatri L, et al. Postoperative dysphagia versus neurogenic dysphagia:Scintigraphic assessment[J]. Ann Otol Rhi-nol Laryngol, 2003, 112(1):20-28.
[33] Huang YH, Chang SC, Kao PF, et al. The value of pharyngeal scintigraphy in predicting videofluoroscopic findings[J]. Am J Phys Med Rehabil, 2013, 92(12):1075-1083.
[34] Akbunar AT, Kiristioglu I, Alper E, et al. Diagnosis of orotracheal aspiration using radionuclide salivagram[J]. Ann Nucl Med, 2003, 17(5):415-416.
[35] Siraj QH, Mcclenahan R, Hilson AJ. A novel scintigraphic ap-proach for the detection and evaluation of bronchopulmonary aspi-ration[J]. J Pak Med Assoc, 2004, 54(4):219-221.
[36] Richter T, Bergmann R, Knels L, et al. Pulmonary blood flow in-creases in damaged regions directly after acid aspiration in rats[J]. Anesthesiology, 2013, 119(4):890-900.

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备注/Memo

备注/Memo:
收稿日期:2014-10-29。
通讯作者:陈跃,Email:chenyue5523@126.com
更新日期/Last Update: 1900-01-01