[1]谭兴普,黄艳.99Tcm-MIBI亲肿瘤延迟断层显像对肺占位病灶的诊断价值[J].国际放射医学核医学杂志,2010,34(5):297-299.[doi:10.3760/cma.j.issn.1673-4114.2010.05.012]
　TAN Xing-pu,HUANG Yan.Diagnostic value of tumor positive delay tomogram imaging with 99Tcm-MIBI for pulmonary neoplasms[J].International Journal of Radiation Medicine and Nuclear Medicine,2010,34(5):297-299.[doi:10.3760/cma.j.issn.1673-4114.2010.05.012]
点击复制

99Tcm-MIBI亲肿瘤延迟断层显像对肺占位病灶的诊断价值(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
34
期数:
2010年第5期
页码:
297-299
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Diagnostic value of tumor positive delay tomogram imaging with 99Tcm-MIBI for pulmonary neoplasms
作者:
谭兴普;  黄艳
518104, 广东省深圳市宝安区沙井人民医院呼吸科
Author(s):
TAN Xing-pu;  HUANG Yan
Department of Respiration, Shenzhen Baoan Sharing People’s Hospital, Guang Dong Shenzhen 518104, China
关键词:
肺肿瘤; 肺炎; 肺结核; 99m锝甲氧基异丁基异腈; 放射性核素显像
Keywords:
Lung neoplasm; Pneumonia; Tuberculosis pulmonary; Technetium Tc 99m sestamibi; Radionnuclide imaging
DOI:
10.3760/cma.j.issn.1673-4114.2010.05.012
摘要:
目的 探讨99Tcm-MIBI亲肿瘤延迟断层显像在肺部占位病灶中的诊断价值。方法 对28例肺部占位患者静脉注射740 MBq99Tcm-MIBI后1 h行延迟断层显像,以占位病灶(T)/对侧相应部位或邻近正常组织(N)的摄取比值T/N>1.31为恶性病变标准对肺部占位病灶进行良、恶性判断。结果 肺占位在良性占位组显像剂浓聚多数轻度增强,恶性占位组多数明显增强。肺占位诊断恶性病灶的灵敏度为76.9%,特异度为86.7%,假阳性为13.3%,假阴性为23.1%。结论 99Tcm-MIBI亲肿瘤延迟断层显像以其无创、灵敏、图像质量及特异性较高的优点,可作为在肺占位病灶良、恶性鉴别诊断的重要辅助检查手段。
Abstract:
Objective To investigate the diagnotic value of tumor positive delay tomogram imaging with 99Tcm-methoxyisobutylisonitrile(MIBI) for pulmonary neoplasm. Methods Twenty-eight cases pulmonary neoplasms traded by 99Tcm-MIBI imaging,then performed tornogram imaging after 1h. By the uptake ratio value exceeding 1.31 between pulmonary neoplasm(T)and normal tissue on the opposite side or vicinity tissue (N),benign or malignant was diagnosted. Results The malignant pulmonary neoplasm had abnormal high uptake, but benign pulmonary neoplasm had light uptake. The sensitivity and specificity of 99Tcm-MIBI imaging for the malignant pulmonary neoplasm were 76.9% and 86.7% respectively, the false positive and false negative rate were 13.3% and 23.1% respectively. Conclusions Tumor positive delay tomogram imaging with 99Tcm-MIBI for pulmonary neoplasm is an important detection in differentiating benign and malignant, it has high sensitivity, specificity, picture quanlity and no wound again.

参考文献/References:

[1] 唐明灯,佘志廉,倪雷春,等.99Tcm-MIBI肿瘤显像对肺结节的诊断价值.中华核医学杂志,2003,23(6):358-359.
[2] 张永学.医学影像技术丛书核医学分册.武汉:湖北科学出版社,2000:196.
[3] 张永学,冯敢生,谢明星.影像医学与核医学诊疗常规.湖北:湖北科学出版社,2006:748.
[4] 李少林,张永学.核医学.6版.北京:人民卫生出版社,2004:164-166.

相似文献/References:

[1]麦卫平,张永林.能谱CT成像在肺癌诊断中的应用研究进展[J].国际放射医学核医学杂志,2016,40(1):77.[doi:10.3760/cma.j.issn.1673-4114.2016.01.015]
　Mai Weiping,Zhang Yonglin.Research progress of spectral imaging in the diagnosis of lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):77.[doi:10.3760/cma.j.issn.1673-4114.2016.01.015]
[2]霍小东,王慧星,阎卫亮,等.血管内皮抑制素对125I近距离照射裸鼠肺癌移植瘤的增敏效应研究[J].国际放射医学核医学杂志,2016,40(5):357.[doi:10.3760/cma.j.issn.1673-4114.2016.05.006]
　Huo Xiaodong,Wang Huixing,Yan Weiliang,et al.Sensitization effect of endostatin for 125I brachytherapy on transplanted tumor in nude mice[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(5):357.[doi:10.3760/cma.j.issn.1673-4114.2016.05.006]
[3]张艳兰,孙琦婷,武萍,等.呼吸门控PET/CT对于肺癌放疗靶区勾画的指导[J].国际放射医学核医学杂志,2015,39(2):105.[doi:10.3760/cma.j.issn.1673-4114.2015.02.001]
　Zhang Yanlan,Sun Qiting,Wu Ping,et al.Guiding the target delineation in radiation therapy of lung cancer by respiratory gated PET/CT[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):105.[doi:10.3760/cma.j.issn.1673-4114.2015.02.001]
[4]江涛,陈跃.放射性核素显像在肺吸入诊断中的应用进展[J].国际放射医学核医学杂志,2015,39(2):165.[doi:10.3760/cma.j.issn.1673-4114.2015.02.014]
　Jiang Tao,Chen Yue.Advances in radionuclide imaging for pulmonary aspiration[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):165.[doi:10.3760/cma.j.issn.1673-4114.2015.02.014]
[5]张高潮,马丽,寇莹,等.99Tcm-tetrofosmin SPECT诊断肺部肿瘤的临床价值[J].国际放射医学核医学杂志,2015,39(4):303.[doi:10.3760/cma.j.issn.1673-4114.2015.04.007]
　Zhang Gaochao,Ma Li,Kou Ying,et al.Clinical value of 99Tcm-tetrofosmin SPECT in the diagnosis of lung neoplasms[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(5):303.[doi:10.3760/cma.j.issn.1673-4114.2015.04.007]
[6]付畅,史大鹏,徐俊玲,等.不同组织学类型肺癌患者大脑静息葡萄糖代谢改变研究[J].国际放射医学核医学杂志,2014,38(2):75.[doi:10.3760/cma.j.issn.1673-4114.2014.02.002]
　Fu Chang,Shi Dapeng,Xu Junling,et al.The preliminary study of brain glucose metabolism changes in patients with lung cancer of different histological types[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(5):75.[doi:10.3760/cma.j.issn.1673-4114.2014.02.002]
[7]张俊涛.晚期肺癌125I粒子植入治疗近期疗效观察[J].国际放射医学核医学杂志,2014,38(2):94.[doi:10.3760/cma.j.issn.1673-4114.2014.02.006]
　Zhang Juntao.Short-term efficacy of 125I seeds implantation in the treatment of advanced lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(5):94.[doi:10.3760/cma.j.issn.1673-4114.2014.02.006]
[8]杨心蕊,卫华,郝新忠,等.过敏性肺炎伴左肺动脉栓塞18F-FDGPET/CT误诊肺癌一例[J].国际放射医学核医学杂志,2014,38(2):135.[doi:10.3760/cma.j.issn.1673-4114.2014.02.014]
[9]王芹,杜利清,徐畅,等.白细胞介素21基因联合放射对肺癌细胞生长的协同抑制作用[J].国际放射医学核医学杂志,2014,38(3):161.[doi:10.3760/cma.j.issn.1673-4114.2014.02.005]
　Wang Qin,Du Liqing,Xu Chang,et al.Synergism inhibition effect of adenovirus-mediated IL-21 gene combined with ionizing radiation on the growth of pulmonary carcinoma cells[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(5):161.[doi:10.3760/cma.j.issn.1673-4114.2014.02.005]
[10]朱同华,杨鸿林,钮丽萍.血浆CYFRA21-1和CA125、CA199、CA153联合检测对肺癌的辅助诊断价值[J].国际放射医学核医学杂志,2014,38(5):304.[doi:10.3760/cma.j.issn.1673-4114.2014.05.007]
　Zhu Tong-hua,Yang Hong-lin,Niu Li-ping.The value of combined detection of plasma CYFRA21-1 and CA125, CA199, CA153 in the accessory diagnosis of lung cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(5):304.[doi:10.3760/cma.j.issn.1673-4114.2014.05.007]

备注/Memo

备注/Memo:
收稿日期:2010-04-04。
通讯作者:谭兴普,E-mail:tanxinpu@yahoo.com.cn
更新日期/Last Update: 1900-01-01