[1]卢晓莉,张俊,王峰,等.影像学技术对转移性淋巴结的诊断价值[J].国际放射医学核医学杂志,2011,35(6):334-338.[doi:10.3760,cma.j.issn.1673-4114.2011.06.004]
 LU Xiao-li,ZHA NG Jun,WANG Feng,et al.Diagnosis value of imaging techniques in assessing lymph nodes metastasis[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(6):334-338.[doi:10.3760,cma.j.issn.1673-4114.2011.06.004]
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影像学技术对转移性淋巴结的诊断价值(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第6期
页码:
334-338
栏目:
实验核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Diagnosis value of imaging techniques in assessing lymph nodes metastasis
作者:
卢晓莉 张俊 王峰 王自正
南京医科大学附属南京第一医院核医学, 南京 210006
Author(s):
LU Xiao-li ZHA NG Jun WANG Feng WANG Zi-zheng
Department of Nuclear Medicine, Frist Hospital of Nanjing Medical Uni-versity, Nanjing 210006, Chin
关键词:
淋巴结肿瘤转移超声检查磁共振成像体层摄影术X线计算机正电子发射断层显像术
Keywords:
Lymph nodeNeoplasm metastasisUltrasonographyMagnetic resonance imagingTomographyX-ray computedPositron emission tomograph
DOI:
10.3760,cma.j.issn.1673-4114.2011.06.004
摘要:
早期准确地评估肿瘤患者的淋巴结及难以解释的淋巴结病变,对选择合适的治疗计划及预后的判断至关重要。目前,淋巴结大小仍然是区别转移性和非转移性淋巴结的最常用的指标,但是其准确性不高,为了提高对淋巴结良恶性病变评估的准确性,需要找到一种新的显像方法,它并不仅仅局限于对淋巴结解剖上的评估,还可以在细胞水平对淋巴结生理和生化过程进行直观和定量评估。不同的影像学方法在评价局部淋巴结时具有各自的特点,随着分子影像学的发展,功能成像技术在淋巴结诊断方面占据着越来越重要的地位。该文旨在对诊断淋巴结转移的各种影像学技术做一综述。
Abstract:
Early and accurate evaluate the patients’ lymph nodes and the unexplained lymphade. nopathy are crucial to select the proper treatment plan and dpredicting prognosis.Although size measure-ments are still the most widely used method for discriminating malignant from non-malignant lymph nodes,it possesses a low accuracy.In order to increase the accuracy of evaluate the malignant and benign lymph nodes,it is necessary to find a new imaging method which is not just evaluate the anatomical structures of the lymph node,hut also allow visualization and quantification of physiological and biochemical processes at the cellular level.Every imaging technique has its own characteristic to evaluate local lymph nodes,with the persistent development of molecularimaging,functional imaging technique has played a more and more important role in the diagnosis of lymph nodes.This article mainly reviewed and discussed imaging techniques in the evaluation of lymph nodes.

参考文献/References:

[1] Jemal A,Siegel R,Xu JQ,et al.Cancer statistics,2010.CA Cancer J Clin,2010,60(5):277-300.
[2] Solbiati L,Cioffi V,Ballarati E.Uhrasonography of the neck.Radiol Clin North Am,1992,30(5):941-954.
[3] 陈晓辉,柳硕岩,吴周贵.彩超检查对食管癌颈部淋巴结转移的诊断价值(附150例分析).福建医药杂志,2009,31(3):108-110.
[4] 于海容,朱强,乔华.超声对头颈部恶性肿瘤颈部淋巴结转移的诊断价值.山东医药,2009,49(48):77-79
[5] Rubaltelli L,Corradin S,Dorigo A,et al.Automated quantitative evaluation of lymph node perfusion on contrast-enhanced sonography.AJR Am J Roentgenol,2007,188(4):977-983.
[6] Valls C,Andia E,Sanchez A,et al.Dual-phase helical CT of pancreatic adenocarcinoma:assessment of resectability before surgery.AJR Am J Roentgenol,2002,178(4):821-826.
[7] 陆秀伟,谢筱唏,徐莉萍,等.胆囊癌淋巴结转移的多层螺旋CT分析.实用放射学杂志,2010,26(9):1295-1297.
[8] 乔英,李健丁,张瑞平,等.CT三期增强扫描对胃癌淋巴结转移的诊断价值.放射学实践,2006,21(5):507-510.
[9] Rumboldt Z,Al-Okaili R,Deveikis JP.Perfusion CT for head and neck tumors:pilot study.AJNR Am J Neuroradiol,2005,26(5):1178-1185.
[10] de Bondt RB,Hoeberigs MC,Nelemans PJ,et al.Diagnostic accuracy and additional value of diffusion-weighted imaging for discrimination of malignant cervical lymph nodes in head and neck squamous cell carcinoma.Neuroradiology,2009,51(3):183-192.
[11] Eiber M,Beer AJ,Holzapfel K,et al.Preliminary results for characterization of pelvic lymph nodes in patients with prostate cancer by diffusion-weighted MR-imaging.Invest Radiol,2010,45(1):15-23.
[12] Nakai G,Matsuki M,Inada Y,et al.Detection and evaluation of pelvic lymph nodes in patients with gynecologic malignancies using body diffusion-weighted magnetic resonance imaging.J Comput Assist Tomogr,2008,32(5):764-768.
[13] Kwee TC,Takabara T,Luijten PR,et al.ADC measurements of lymph nodes:inter-and intra-observer reproducibility study and all overview of the literature.Eur J Radiol,2010,75(2):215-220.
[14] Saokar A,Braschi M,Harisinghani M.Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging.Abdom Imaging,2006,31(6):660-667.
[15] Harisinghani MG,Saini S,Weissleder R,et al.MR lymphangiography using uhrasmall super paramagnetic iron oxide in patients with primary abdominal and pelvic malignancies:radiographic-pathologic correlation.AJR Am J Roentgenol,1999,172(5):1347-1351.
[16] 吴元魁,许乙凯,黄其鎏.超顺磁氧化铁粒子增强MRI区分肿瘤转移性与良性淋巴结的实验研究.中华放射学杂志,2002,36(6):562-566.
[17] Pandharipande PV,Mora JT,Uppot RN,et al.Lymphotropie nanoparticle-enhaneed MRI for independent prediction of lymph node malignancy:a logistic regression model.AJR Am J Roentgenol,2009,193(3):W230-W237.
[18] Will O,Purkayastha S,Chan C,et al.Diagnostic precision of nanoparticle-enhanced MRI for lymph-node metastases:a meta-analysis.Lancet Oncol,2006,7(1):52-60.
[19] Thoeny HC,Triantafyllou M,Birkhaeuser FD,et al.Combined uhrasmall superparamagnetic particles of iron oxide-enhanced and diffusion-weighted magnetic resonance imaging reliably detect pelvic lymph node metastases in normal-sized nodes of bladder and prostate cancer patients.Eur Urol,2009,55(4):761-769.
[20] Fletcher JW,Djulbegovie B,Soares HP,et al.Recommendations on the use of 18F-FDG PET in oncology.J Nucl Med,2008,49(3):480-508.
[21] Kyzas PA,Evangelou E,Denaxa-Kyza D,et al.18F-fluorodeoxyglucose positron emission tomography to evaluate cervical node metastases in patients with head and neck squamous cell carcinoma:a meta-analysis.J Nail Cancer Inst,2008,100(10):712-720.
[22] Gould MK,Kuschner WG,Rydzak CE,et al.Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non-small-cell lung cancer:a meta-analysis.Ann Intern Med,2003,139(11):879-892.
[23] Basu S,Kung J,Houseni M,et al.Temporal profile of fluorodeoxyglucose uptake in malignant lesions and normal organs over extended time periods in patients with lung carcinoma:implications for its utilization in assessing malignant lesions.Q J Nucl Med Mol Imaging,2009,53(1):9-19.
[24] Kwee TC,Basu S,Torigian DA,et al.Defining the role of modern imaging techniques in assessing lymph nodes for metastasis in cancer:evolving contribution of PET in this setting.Eur J Nucl Med Mol Imaging,2011,38(7):1353-1366.
[25] Jeong HS,Back CH,Son YI,et al.Use of integrated 18F-FDG PET/CT to improve the accuracy of initial cervical nodal evaluation in patients with head and neck squamous cell carcinoma.Head Neck,2007,29(3):203-210.

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备注/Memo

备注/Memo:
收稿日期:2011-08-03。
基金项目:国家自然科学基金(81171383)
通讯作者:王自正(Email:ZZWan9136@yahoo.com.cn)
更新日期/Last Update: 1900-01-01