[1]白剑强,夏群,胡永成.放射性核素骨显像在脊柱转移瘤诊断中的价值[J].国际放射医学核医学杂志,2011,35(1):28-30.[doi:10.3760/cma.j.issn.1673-4114.2011.01.008]
 BAI Jian-qiang,XIA Qun,HU Yong-cheng.Evaluate the diagnostic value of radionuclide bone imaging of metastatic spine tumors[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(1):28-30.[doi:10.3760/cma.j.issn.1673-4114.2011.01.008]
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第1期
页码:
28-30
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Evaluate the diagnostic value of radionuclide bone imaging of metastatic spine tumors
作者:
白剑强 夏群 胡永成
天津医院脊柱外科, 天津 300211
Author(s):
BAI Jian-qiang XIA Qun HU Yong-cheng
Deportment of Spine, Tianjin Hospital, Tianjin 300211, China
关键词:
脊椎肿瘤放射胜核素显像
Keywords:
Spinal neoplasmsBoneRadionuclide imaging
DOI:
10.3760/cma.j.issn.1673-4114.2011.01.008
摘要:
脊柱转移瘤(MST)可发生于原发恶性肿瘤临床的各个阶段,传统X线片发现时多为中晚期病变;CT容易漏诊,不能直接显示脊髓的异常;MRI耗时长,病痛的患者不易配合,影响图像的质量。常规骨扫描能够对整个骨骼进行扫描,但特异性不高。核素SPECT骨显像可提高对MST诊断的敏感性和特异性,提示病灶累及的解剖结构或分布形态,并能定量分析放射性浓聚灶;PET-CT能够清楚鉴别脊柱病变,实现早期诊断,并可早期评估化疗或放疗疗效。该文进一步阐述核素骨显像在MST早期诊断中的价值。
Abstract:
Metastatic spine tumors (MST)can occur in many primary malignant tumors, but X-ray cannot find early metastatic disease; CT scans can not directly show abnormity of the spinal marrow; MRI need a long time, patients with spinal tumors can hardly to be suffered which will affect image quality. Conventional bone scan has the ability to scan the entire skeleton, but the specificity is not high. However, the sensitivity and specificity can be improved about the diagnosis of MST by bone SPECT imaging, the distribution of the anatomical structure or morphology of the metastatic spinal tumors can be clearly displayed. PET-CT could detect the metastases of spine and other pans of the body sensitively and accurately, primary tumors that were unknown before examination could be found at the same time. This paper describes the diagnostic value of radionuclide bone scintigraphy of MST.

参考文献/References:

[1] Ratliff JK, Cooper PR. Metastatic spine tumors. South Med J, 2004, 97(3):246-253.
[2] Pascal-Moussellard H, Broc G,Pointillart V,et al. Complications of vertebral metastasis surgery. Eur Spine J, 1998, 7(6):438-444.
[3] Aebi M. Spinal metastasis in the elderly. Eur Spine J, 2003, 12(Suppl 2):5202-5213.
[4] Reinartz P, Schafeldt J, Sabri O,et al. Benign versus malignant os-seour lesions in the lumbar vertebrae:differentiation by means of bone SPET. Eur J Nucl Med, 2000, 27(6):721-726.
[5] Minart D, Vallée JN, Cormier E,et al. Percutaneous coaxial transpedicular biopsy of vertebral body lesions during vertebro-plasty. Neuroradiology, 2001, 43(5):409-412.
[6] Walker MP, Yaszemski MJ, Kim CW,et al. Metastatic disease of the spine:evaluation and treatment. Clin Orthop, 2003, 415(Suppl):S165-S175.
[7] Prott FJ, Micke O,Schlehuber E, et al. The value of magnetic reso-nance tomography(MRI) with reference to economic aspects of ra-diotherapy planning of vertebral metastases. A cost benefit anal-ysis. Radiology, 2002, 42(5):388-391.
[8] 曹来宾,王明安,徐爱德,等. 1047例骨转移瘤的影像学诊断. 中华放射学杂志,1997, 31(8):547-551.
[9] 朱岩,梁文杰,向卫国,等.CT对脊杜转移瘤的诊断价值.中国矫形外科杂志,2006, 14(23):1801-1803.
[10] Parikh SN, Crawford AH. Orthopaedic implications in the manage-ment of pediatric vertebral and spinal cord tumors:a retrospective review. Spine,2003, 28(20):2390-2396.
[11] Spuentrup E, Buecker A, Adam G,et al. Diffusion-weighted MR imaging for differentiation of benign fracture edema and tumor in-filtration of the vertebral body. AJR Am J Roentgenol, 2001, 176(2):351-358.
[12] Galasko CS. Skeletal metastases.Clin Orthop Relat Res,1986, 210:18-30.
[13] 屈婉莹.充分发挥放射性核素骨显像的优势.中华核医学杂志, 2004, 24(4):197-198.
[14] Kobayashi K, Okuyama C, Kubota T,et al. Do short-time SPECT images of bone scintigraphy improve the diagnostic value in the e-valuation of solitary lesions in the thoracic spine in patients with extraskeletal malignancies?.Ann Nucl Med, 2005,19(7):557-566.
[15] Reinartz P, Schaffeldt J, Sabri O,et al.Benign versus malignant os-seour lesions in the lumbar vertebrae:differentiation by means of bone SPET. Eur J Nucl Med, 2000, 27(6):721-726.
[16] Even-Spair E, Martin RH, Barnes DC, et al. Role of SPECT in dif-ferentiating malignant from benign lesions in the lower thoracic and lumbar vertebrae.Radiology,1993,187(1):193-198.
[17] Büll U, Schuster H, Pfeifer JP,et al. Bone-to-bone,joint-to-bone and joint-to-joint ratios in normal and diseased skeletal states using re-gion-of-interest technique and bone-seeking radiopharmaceuti-cals. Nuklearmedizin, 1977, 16(3):104-112.
[18] Utsunomiya D, Shiraishi S, Imuta M, et al. Added value of SPECT/CT fusion in assessing suspected bone metastasis:comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology, 2006, 238(1):264-271.
[19] Römer W,Nömayr A, Uder M,et al. SPECT-guided CT for evaluat-ing foci of increased bone metabolism classified as indeterminate on SPECT in cancer patients. J Nucl Med, 2006, 47(7):1102-1106.
[20] Sakurai H, Suzuki Y, Nonaka T, et al. FDG-PET in the detection of recurrence of uterine cervical carcinoma following radiation thera-py-tumor volume and FDG uptake value. Gynecol Oncol, 2006, 100(3):601-607.
[21] Tsuchida T, Kosaka N, Sugimoto K, et al. Sacral insufficiency frac-ture detected by FDG-PET/CT:report of 2 cases. Ann Nucl Med, 2006, 20(6):445-448.
[22] Dehdashti F, Siegel BA, Griffeth LK. Benign versus malignant in-traosseous lesions:discrimination by means of PET with 2-[F-18] fluoro-2-decay-D-glucose.Radiology, 1996, 200(1):243-247.
[23] Duarte PS, Zhuang H, Castellucci P, et al. The receiver operating Characteristic curve for the standard uptake value in a group of pa-tients with bone marrow metastasis. Mol Imaging Biol, 2002, 4(2):157-160.

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备注/Memo

备注/Memo:
收稿日期:2010-12-08。
通讯作者:白剑强(Email:baijianqiang2005@126.com)
更新日期/Last Update: 1900-01-01