[1]张汝森,曾旭文,苏梓航,等.125Ⅰ粒子植入治疗脊椎转移瘤的临床价值[J].国际放射医学核医学杂志,2011,35(1):17-19.[doi:10.3760/cma.j.issn.1673-4114.2011.01.005]
　ZHANG Ru-sen,ZENG Xu-wen,SU Zi-hang,et al.Value of CT guided 125I seeds implantation for vertebra metastasis[J].International Journal of Radiation Medicine and Nuclear Medicine,2011,35(1):17-19.[doi:10.3760/cma.j.issn.1673-4114.2011.01.005]
点击复制

125Ⅰ粒子植入治疗脊椎转移瘤的临床价值(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
35
期数:
2011年第1期
页码:
17-19
栏目:
临床核医学
出版日期:
1900-01-01

文章信息/Info

Title:
Value of CT guided 125I seeds implantation for vertebra metastasis
作者:
张汝森;  曾旭文;  苏梓航;  易基群
广州市红十字会医院核医学科, 广州 510220
Author(s):
ZHANG Ru-sen;  ZENG Xu-wen;  SU Zi-hang;  YI Ji-qun
Deportment of Nuclear Medicine, Guangzhou Red Cross Hospital, Guangzhou 510220, China
关键词:
脊椎肿瘤; 肿瘤转移; 碘放射性同位素; 近距离放射疗法
Keywords:
Spinal neoplasms; Neoplasms metastasis; Iodine radioisotopes; Brachytherapy
DOI:
10.3760/cma.j.issn.1673-4114.2011.01.005
摘要:
目的 探讨125Ⅰ粒子植入治疗脊椎转移瘤的初步疗效。方法 对15例转移瘤患者的22处病灶于术前制订125Ⅰ粒子植入计划,确定粒子数量和分布。在CT引导下植入125Ⅰ粒子,治疗后3~6个月观察疼痛缓解情况和瘤灶大小变化。结果 22处脊椎和椎旁转移瘤植入粒子后,疼痛完全缓解(0级)14处,部分缓解(Ⅰ级)6处,轻微缓解(Ⅱ级)2处,总有效率为90.9%(u=5.41,P<0.001);脊椎和椎旁转移瘤的瘤灶大小变化:4处完全缓解,12处部分缓解,6处病变稳定,局部控制率为72.7%。结论 CT引导下125Ⅰ粒子植入治疗脊椎转移瘤是一种安全、微创、疗效好的方法。
Abstract:
Objective To evaluate the clinical value of 125I seeds implantation for vertebra metastasis. Methods By CT guide, 125I seeds were implanted in 22 vertebra metastasis of 15 patients. 3-6 months later, pain and metastasis biggest diameter were observed to judge therapeutic effect. Results In 22 spinal and paraspinal metastases after implantation of particles, complete remission of pain (0 grade)14, partial remission (Ⅰ grade)6, a slight relief (Ⅱ grade)2, the total effective rate was 90.9% (u=5.41, P<0.001). Change of spinal and paraspinal metastases size:4 complete remission, 12 partial response, 6 stable disease, local control rate was 72.7%. Conclusion CT guided 125I seed implantation in vertebra metastasis is safe, minimally invasive, and possesses a high efficacy.

参考文献/References:

[1] 宋献文.脊椎转移癌.国外医学肿瘤学分册,1982, 9(5):193-197.
[2] Block T, Czempiel H, Zimmermann F. Transperineal permanent seed implantation of "low-risk" prostate cancer:5-year-experiences in 118 patients. Strahlenther Onkol, 2006, 182(11):666-671.
[3] 王俊杰,黄毅,冉维强,等.超声引导125I粒子治疗前列腺癌引起的直肠并发症.中华放射医学与防护杂志,2007, 27(2):172-174.
[4] 柴树德,郑广钧,毛玉权,等.CT引导下经皮穿刺种植放射性125I粒子治疗晚期肺癌.中华放射肿瘤学杂志,2004, 13(4):291-293.
[5] 郑磊,张杰,宋铁砾,等. CT引导下125I粒子组织间放疗在口腔癌颈淋巴结转移的初步应用.现代口腔医学杂志,2008, 22(3):229-231.

相似文献/References:

[1]廖光星,冷志欣,肖国有.前列腺癌骨转移影像诊断方法研究进展[J].国际放射医学核医学杂志,2016,40(6):464.[doi:10.3760/cma.j.issn.1673-4114.2016.06.012]
　Liao Guangxing,Leng Zhixin,Xiao Guoyou.Progress of imaging in the diagnosis of bone metastases of prostate cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(1):464.[doi:10.3760/cma.j.issn.1673-4114.2016.06.012]
[2]张胤,陈跃.18F-氟化钠PET/CT诊断肿瘤骨转移应用进展[J].国际放射医学核医学杂志,2015,39(1):96.[doi:10.3760/cma.j.issn.1673-4114.2015.01.020]
　Zhang Yin,Chen Yue.Application progress of 18F-NaF PET/CT in the diagnosis of neoplasm metastases[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(1):96.[doi:10.3760/cma.j.issn.1673-4114.2015.01.020]
[3]徐金苹,袁德晓,张江虹,等.辐射诱导的外泌体在肿瘤细胞侵袭转移中的作用[J].国际放射医学核医学杂志,2015,39(2):144.[doi:10.3760/cma.j.issn.1673-4114.2015.02.009]
　Xu Jinping,Yuan Dexiao,Zhang Jianghong,et al.The role of radiation-induced exosomes in tumor invasion and metastasis[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(1):144.[doi:10.3760/cma.j.issn.1673-4114.2015.02.009]
[4]刘雪辉,李洪均,于鸿煦.SPECT/CT融合显像对可疑骨转移灶的诊断效能[J].国际放射医学核医学杂志,2015,39(3):201.[doi:10.3760/cma.j.issn.1673-4114.2015.03.003]
　Liu Xuehui,Li Hongjun,Yu Hongxu.Diagnostic efficacy of SPECT/CT fusion imaging in assessing possible bone metastases[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(1):201.[doi:10.3760/cma.j.issn.1673-4114.2015.03.003]
[5]桂继琮,刘兴党.镭-223氯化物治疗去势抵抗性前列腺癌骨转移的研究进展[J].国际放射医学核医学杂志,2015,39(3):268.[doi:10.3760/cma.j.issn.1673-4114.2015.03.018]
　Gui Jicong,Liu Xingdang.Development in the study of radium-223 chloride for treating castration-resistant prostate carcinoma with bone metastases[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(1):268.[doi:10.3760/cma.j.issn.1673-4114.2015.03.018]
[6]高平,王茜,赵赟赟,等.99Tcm-MDP SPECT/CT显像用于骨肉瘤肺转移的诊断[J].国际放射医学核医学杂志,2014,38(3):148.[doi:10.3760/cma.j.issn.1673-4114.2014.03.002]
　Gao Ping,Wang Qian,Zhao Yunyun,et al.99Tcm-MDP SPECT/CT used in diagnosis of pulmonary metastasis from osteosarcoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(1):148.[doi:10.3760/cma.j.issn.1673-4114.2014.03.002]
[7]凌彩霞,肖国有.SPECT/CT骨断层显像及在恶性肿瘤骨转移诊断中的临床价值[J].国际放射医学核医学杂志,2014,38(4):275.[doi:10.3760/cma.j.issn.1673-4114.2014.04.016]
　Ling Caixia,Xiao Guoyou.The clinical value of SPECT/CT bone tomography in the diagnosis of malignant tumor metastasis[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(1):275.[doi:10.3760/cma.j.issn.1673-4114.2014.04.016]
[8]刘超,邓智勇,刘鹏杰,等.89SrCL2与唑来膦酸联合治疗乳腺癌转移性骨肿瘤的疗效分析[J].国际放射医学核医学杂志,2014,38(5):300.[doi:10.3760/cma.j.issn.1673-4114.2014.05.006]
　Liu Chao,Deng Zhi-yong,Liu Peng-jie,et al.Analysis on the curative effect of combination therapy with zoledronic acid and 89SrCL2 on bone tumor with breast cancer metastasis[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(1):300.[doi:10.3760/cma.j.issn.1673-4114.2014.05.006]
[9]王宇峰,刘海娜,张居洋,等.SPECT/CT融合显像对乳腺癌骨转移的诊断价值[J].国际放射医学核医学杂志,2014,38(6):387.[doi:10.3760/cma.j.issn.1673-4114.2014.06.010]
　Wang Yu-feng,Liu Hai-na,Zhang Ju-yang,et al.Clinical value of SPECT/CT fusion imaging in diagnosing metastatic bone lesions in breast cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2014,38(1):387.[doi:10.3760/cma.j.issn.1673-4114.2014.06.010]
[10]赵红光,徐松柏,关锋,等.骶骨脊索瘤伴肺转移18F-FDG PET/CT显像一例[J].国际放射医学核医学杂志,2013,37(2):128.[doi:10.3760/cma.j.issn.1673-4114.2013.02.017]

备注/Memo

备注/Memo:
收稿日期:2010-11-15。
通讯作者:张汝森(Email:Zhang-rs@163.com)
更新日期/Last Update: 1900-01-01